phlove win
IRVINE, Calif., Dec. 04, 2024 (GLOBE NEWSWIRE) -- Oncocyte Corp. (NASDAQ: OCX), a diagnostics technology company, today announced the publication of favorable data regarding its DetermaCNITM assay. In a paper recently published in the journal Acta Neuropathologica Communications, DetermaCNI showed promise as a liquid biopsy method for diagnosing and profiling central nervous system tumors by measuring somatic copy number aberrations (SCNAs) in cerebrospinal fluid. For context, copy number instability (CNI) is a scientifically well-known hallmark of cancer. DetermaCNITM is a patented approach to measuring CNI for the diagnosis and monitoring of cancer. Nearly 300,000 patients in the U.S. each year face primary brain tumors or brain metastasis 1 . The current standard of care for the confirmation and classification of brain tumors often involves high-risk, highly invasive biopsy of brain tissue. Thus, a liquid biopsy method for diagnosing brain tumors could offer significant benefits over currently available methods, representing a potential $300 million U.S. market opportunity. Among the study authors were Oncocyte Chief Science Officer Ekke Schuetz and Senior R&D Director Julia Beck. "This was a proof of principle study to assess whether copy number instability could be measured in the cerebrospinal fluid of patients with brain cancer. The findings suggest that a significant number of the nearly 300,000 patients diagnosed with brain tumors every year in the U.S. could benefit from DetermaCNI,” Dr. Schuetz said. "We congratulate the research team in Frankfurt on the publication of this study in an area of high unmet need.” As noted in the paper, the gold standard for precise diagnostic classification of brain tumors requires a biopsy, with risks including limited sensitivity and failing to measure the diverse potential regions of the tumor. SCNAs were observed in the cerebrospinal fluid of ten out of the 12 patients with confirmed central nervous system cancers. SCNAs were not observed in any of the 11 patients with benign or unclear central nervous system lesions. The detection of SCNAs is highly specific for tumor-derived cell-free DNA (cfDNA). Overall, this new study demonstrates DetermaCNI's potential for providing a molecularly informed diagnosis of central nervous system cancers, mapping tumor heterogeneity, tracking tumor evolution, and surveilling tumor patients through a liquid biopsy of cerebrospinal fluid. Oncocyte believes this study validates the future clinical potential for DetermaCNI, as well as the direction of the company's research and development pipeline, which is designed to drive sustained rapid growth over the next decade. Oncocyte's mission is to democratize access to molecular diagnostic testing to improve patient outcomes. The company is investing in developing products to serve the separate verticals of organ transplant testing and oncology. Oncocyte is presently commercializing its transplant product line, which includes the VitaGraftTM and GraftAssureTM tests. It expects to commercialize its oncology assays over the next two years. _______________ 1 "Brain Metastases.” MD Anderson Cancer Center , www.mdanderson.org/cancer-types/brain-metastases.html. And "Brain Tumor Facts.” National Brain Tumor Society , 20 Feb. 2024, braintumor.org/brain-tumors/about-brain-tumors/brain-tumor-facts/. About Oncocyte Oncocyte is a diagnostics technology company. The Company's tests are designed to help provide clarity and confidence to physicians and their patients. VitaGraftTM is a clinical blood-based dd-cfDNA solid organ transplantation monitoring test. GraftAssureTM is a research use only (RUO) blood-based solid dd-cfDNA organ transplantation monitoring test kit for decentralized use. DetermaIOTM is a gene expression test that assesses the tumor microenvironment to predict response to immunotherapies. DetermaCNITM is a blood-based monitoring tool for monitoring therapeutic efficacy in cancer patients. For more information about Oncocyte, please visit https://oncocyte.com/ . For more information about our products, please visit the following web pages: VitaGraft KidneyTM - https://oncocyte.com/vitagraft-kidney/ VitaGraft Liver TM - https://oncocyte.com/vitagraft-liver/ GraftAssureTM - https://oncocyte.com/graftassure/ DetermaIOTM - https://oncocyte.com/determa-io/ DetermaCNITM - https://oncocyte.com/determa-cni/ VitaGraftTM, GraftAssureTM, DetermaIOTM, and DetermaCNITM are trademarks of Oncocyte Corporation. CONTACT: Jeff Ramson PCG Advisory (646) 863-6893 [email protected] Forward-Looking Statements Any statements that are not historical fact (including, but not limited to statements that contain words such as "will,” "believes,” "plans,” "anticipates,” "expects,” "estimates,” "may,” and similar expressions) are forward-looking statements. These statements include those pertaining to, among other things, the belief that the new study validates the future clinical potential for DetermaCNI, as well as the direction of the company's research and development pipeline, the expectation that Oncocyte will commercialize its oncology assays over the next two years, and other statements about the future expectations, beliefs, goals, plans, or prospects expressed by management. Forward-looking statements involve risks and uncertainties, including, without limitation, risks inherent in the development and/or commercialization of diagnostic tests or products, uncertainty in the results of clinical trials or regulatory approvals, the capacity of Oncocyte's third-party supplied blood sample analytic system to provide consistent and precise analytic results on a commercial scale, potential interruptions to supply chains, the need and ability to obtain future capital, maintenance of intellectual property rights in all applicable jurisdictions, obligations to third parties with respect to licensed or acquired technology and products, the need to obtain third party reimbursement for patients' use of any diagnostic tests Oncocyte or its subsidiaries commercialize in applicable jurisdictions, and risks inherent in strategic transactions such as the potential failure to realize anticipated benefits, legal, regulatory or political changes in the applicable jurisdictions, accounting and quality controls, potential greater than estimated allocations of resources to develop and commercialize technologies, or potential failure to maintain any laboratory accreditation or certification. Actual results may differ materially from the results anticipated in these forward-looking statements and accordingly such statements should be evaluated together with the many uncertainties that affect the business of Oncocyte, particularly those mentioned in the "Risk Factors” and other cautionary statements found in Oncocyte's Securities and Exchange Commission (SEC) filings, which are available from the SEC's website. You are cautioned not to place undue reliance on forward-looking statements, which speak only as of the date on which they were made. Oncocyte undertakes no obligation to update such statements to reflect events that occur or circumstances that exist after the date on which they were made, except as required by law.
Some state lawmakers and companies will be preparing to roll back major Diversity, Equity and Inclusion (DEI) policies that are present in nearly every major U.S. industry, including the military, according to experts and a Republican attorney general. The DEI topic was back in the news last week due to an intense exchange between lawmakers during a markup of the "Dismantle DEI" bill in the House. Progressive firebrand Rep. Jasmine Crockett, D-Tex., lambasted a Republican congressman who referred to DEI policies as "oppression." "There has been no oppression for the white man in this country," Crockett said. "You tell me which white men were dragged out of their homes. You tell me which one of them got dragged all the way across an ocean and told that you are gonna go work, we are gonna steal your wives, we are gonna rape your wives. That didn’t happen. That is oppression." The incoming Trump administration will likely target many DEI initiatives. In 2020, then-President Trump issued an executive order to ban "divisive" training for federal contractors. And the House Oversight Committee held a hearing this week about dismantling DEI policies. "It is a multibillion-dollar industry that pushes a left-wing, far-left ideological orthodoxy in essentially every area of American life, which is why I've begun to call it the DEI enterprise, instead of just DEI, so that people have a sense of what I'm talking about," Devon Westhill, constitutional and civil rights attorney, told Fox News Digital in an interview. Westhill, who researches DEI policies at the Center for Equal Opportunity, a Washington, D.C.-based conservative think tank, said DEI isn't interested in "diversity of thought, true diversity," but rather, it is "interested in racial quotas." Over the last four years, the Biden-Harris administration has encouraged DEI initiatives across several sectors of the federal government. In 2021, Biden widened an executive order directing agencies to assess and "remove barriers" to equal opportunity through DEI policies. Another executive order signed that year was a government-wide initiative to embed DEI principles in federal hiring. The Department of Education has also released reports encouraging DEI on public university campuses. The Biden-Harris administration also invested in DEI programs within the U.S. military. Large corporations across the U.S. have also adopted DEI workplace policies, including Accenture, Johnson & Johnson, Mastercard, Marriott International, Kaiser Permanente, EY (Ernst & Young), Target, Google, Bank of America and American Express. "It wasn't so much a dollars and cents motivation [for corporations]," Will Hild, executive director of Consumer's Research, told Fox News Digital in an interview. "You had it coming from the federal government, where if you wouldn't go along with under the Biden administration, with the DEI regime, they were threatening to sue you, or to claim that you're violating civil rights of minorities. So, it was more a combination of the threat of bad press or government action against these corporations." Hild said he expected to see over the next year many red state attorneys general "start suing these corporations" for hiring based on racial quotas. Consumers have also suffered as a result of DEI policies, he said, arguing that it shifted companies' focus away from the quality of goods. The integration of Environmental, Social and Governance (ESG) and DEI benchmarks has also influenced investment decisions and pension fund strategies. Pension funds have been increasingly incorporating ESG and DEI considerations into their investment processes over the last four years. Iowa Attorney General Brenna Bird said this will be one area of focus her office will examine. "We want to make sure that we are protecting people's pensions, because no one's retirement and life savings should be gambled for these woke ESG and DEI goals," Bird said. "And so that means that our work with that issue will continue, whether it's the investment managers or the proxy advisers, you know, making sure that these pensions are being invested, so that it's there for people when they need it, and not for any kind of social engineering or other types of woke political goals." Fox News Digital reached out to the White House for comment. Originally published as US state lawmakers, companies prepare to push back against diversity, equity and inclusion, 'woke' initiatives: experts
Boston man accused of attacking transgender woman on MBTA train: ‘You’re not a woman, you’re a man’None
San Jose brings losing streak into game against Los Angeles
General Election: Fine Gael and Fianna Fáil predict strong results
Jenkins throws for 3 TDs to carry FIU to 35-24 win over Middle Tennessee
Percentages: FG .424, FT .867. 3-Point Goals: 9-27, .333 (Farell 4-6, R.Felton 3-10, Soumaoro 1-1, LaBeaux 1-2, Woodard 0-1, Riley 0-2, Walker 0-2, Hayes 0-3). Team Rebounds: 1. Team Turnovers: None. Blocked Shots: 4 (R.Felton 3, Walker). Turnovers: 7 (Riley 2, Farell, LaBeaux, R.Felton, Soumaoro, Woodard). Steals: 3 (R.Felton, Riley, Woodard). Technical Fouls: None. Percentages: FG .528, FT .742. 3-Point Goals: 7-15, .467 (Cotton 3-3, Ituka 2-6, Pierre 1-2, Franklin 1-3, Houge 0-1). Team Rebounds: 4. Team Turnovers: None. Blocked Shots: 3 (Nicholson 2, Niagu). Turnovers: 8 (Cotton 2, Pierre 2, Brigham, Franklin, Houge, Ituka). Steals: 5 (Brigham, Cotton, Ituka, Nicholson, Pierre). Technical Fouls: None. .Alphabet Inc. (NASDAQ:GOOGL) Shares Purchased by Mesirow Financial Investment Management Inc.
The AP Top 25 men’s college basketball poll is back every week throughout the season! Get the poll delivered straight to your inbox with AP Top 25 Poll Alerts. Sign up here . ATHENS, Ohio (AP) — AJ Clayton scored 16 points as Ohio beat Robert Morris 84-68 on Saturday. Clayton had seven rebounds for the Bobcats (3-5). Victor Searls scored 14 points and added seven rebounds. Jackson Paveletzke and Aidan Hadaway both scored 11 points. The Colonials (6-3) were led by Josh Omojafo, who recorded 15 points. Antallah Sandlin’El added 14 points for Robert Morris. Alvaro Folgueiras finished with 12 points and seven rebounds. The loss ended a six-game winning streak for the Colonials. ___ The Associated Press created this story using technology provided by Data Skrive and data from Sportradar .SINGAPORE , Nov. 30, 2024 /PRNewswire/ -- Amber DWM Holding Limited ("Amber DWM"), the holding entity of Amber Group's digital wealth management business, known as Amber Premium ("Amber Premium"), today announced that it has entered into a definitive Agreement and Plan of Merger (the "Merger Agreement") with iClick Interactive Asia Group Limited ("iClick" or the "Listco") (NASDAQ: ICLK) and Overlord Merger Sub Ltd. ("Merger Sub"), a Cayman Islands exempted company and a direct, wholly owned subsidiary of the Listco. Under the Merger Agreement, Merger Sub will merge with and into Amber DWM, with Amber DWM continuing as the surviving entity and becoming a wholly-owned subsidiary of the Listco (the "Merger"). Amber DWM's shareholders will exchange all of their issued and outstanding share capital for a mix of newly issued Class A and Class B ordinary shares of the Listco on the terms and conditions set forth therein in a transaction exempt from the registration requirements under the Securities Act of 1933. Wayne Huo , Chief Executive Officer and Director of Amber DWM , said: " We are thrilled to embark on this transformative journey with iClick. This merger represents a significant milestone, bringing together Amber Premium's expertise in digital wealth management and iClick's innovative marketing technology. Together, we aim to redefine the digital financial ecosystem, delivering unparalleled value to our clients and stakeholders. By bridging the worlds of blockchain, fintech and digital marketing, we are unlocking new opportunities to revolutionize how value is created and exchanged in the digital economy ." The transaction values Amber DWM at US$360 million and the Listco at US$40 million by equity value on a fully diluted basis (assuming completion of certain restructuring as set forth in the Merger Agreement). Upon closing of the Merger (the "Closing"), the Amber DWM shareholders and the Listco shareholders (including holders of ADSs) will own approximately 90% and 10%, respectively, of the outstanding shares of the combined company, or 97% and 3% voting power, respectively. The Merger Agreement also contemplates that, upon the Closing, the Listco will change its name to "Amber International Holding Limited" and adopt the tenth amended and restated memorandum and articles of association of the Listco, in each case immediately before the effective time of the Merger (the "Effective Time"), following which the authorized share capital of the Listco shall only consist of Class A ordinary shares and Class B ordinary shares (with different voting powers but equal economic rights), a par value of US$0.001 each. Please refer to the Merger Agreement filed as Exhibit 99.2 to the Form 6-K furnished by the Listco to the SEC on November 29, 2024 for more details. The Listco's board of directors (the "Board") approved the Merger Agreement and other transaction documents, including but not limited to the voting agreement entered into by and among certain shareholders of the Listco (who holds approximately 36% of the outstanding shares representing 71% voting power of the Listco as of the date of this press release), the Listco and Amber DWM (the "Voting Agreement") (collectively, the "Transaction Documents"), and the transactions contemplated thereunder (the "Transactions"), with the assistance of its financial and legal advisors. The Board also resolved to recommend that the Listco's shareholders vote to authorize and approve the Transaction Documents and the Transactions when they are submitted for shareholder approval. In connection with the Transaction, each of the shareholders of Amber DWM immediately prior to the consummation of the Merger is entering into a lock-up agreement with the Listco pursuant to which they have agreed not to transfer the shares received in consideration of the Merger for a period of 12 months following the Merger closing. The completion of the Transactions is subject to the satisfaction of closing conditions set forth in the Merger Agreement, including, among other things, receipt of the Listco's shareholder approval and regulatory/stock exchange approvals (if applicable). The Merger Agreement provides for a long-stop date for any party to terminate the agreement if the Merger is not completed by June 30, 2025 . " This merger represents a transformative opportunity to broaden our business portfolio by integrating Amber Premium's state-of-the-art digital wealth management solutions. By uniting iClick's robust data analytic and enterprise software expertise with Amber Premium's advanced digital wealth management services, we aim to unblock synergies between traditional finance and the rapidly evolving digital asset ecosystem, particularly benefitting corporate and high net worth individual clients ", said Mr. Jian Tang , Chairman, Chief Executive Officer and Co-Founder of iClick . The foregoing description of the Merger Agreement and the Voting Agreement does not purport to be complete and is qualified in its entirety to the full text of the Merger Agreement and the Voting Agreement, which are filed as Exhibits 99.2 and 99.3 to the Form 6-K furnished by the Listco to the SEC on 29, 2024, respectively. Simpson Thacher & Bartlett LLP is serving as U.S. legal counsel to Amber DWM. Cleary Gottlieb Steen & Hamilton LLP is serving as U.S. legal counsel to iClick. About Amber Premium Amber Premium, the business brand behind Amber DWM Holding Limited, is a leading digital wealth management platform offering private banking-level solutions tailored for the dynamic crypto economy. Serving a premium clientele of esteemed institutions and qualified individuals, Amber Premium develops and supports innovative digital wealth management products. Its institutional-grade access and operations makes it the top choice for one-stop digital wealth management services, providing tailored, secure solutions that drive growth in the Web3 economy. About iClick Interactive Asia Group Limited Founded in 2009, iClick Interactive Asia Group Limited (NASDAQ: ICLK) is a renowned online marketing and enterprise solutions provider in Asia . With its leading proprietary technologies, iClick's full suite of data-driven solutions helps brands drive significant business growth and profitability throughout the full consumer lifecycle. For more information, please visit https://ir.i-click.com . Safe Harbor Statement This press release contains certain "forward-looking statements." These statements are made under the "safe harbor" provisions of the U.S. Private Securities Litigation Reform Act of 1995. Statements that are not historical facts, including statements about the pending transactions described herein, and the parties' perspectives and expectations, are forward-looking statements. The words "will," "expect," "believe," "estimate," "intend," "plan" and similar expressions indicate forward-looking statements. Such forward-looking statements are inherently uncertain, and shareholders and other potential investors must recognize that actual results may differ materially from the expectations as a result of a variety of factors. Such forward-looking statements are based upon management's current expectations and include known and unknown risks, uncertainties and other factors, many of which are hard to predict or control, that may cause the actual results, performance, or plans to differ materially from any future results, performance or plans expressed or implied by such forward-looking statements. Such risks and uncertainties include, but are not limited to: (i) risks related to the expected timing and likelihood of completion of the proposed transaction, including the risk that the transaction may not close due to one or more closing conditions to the transaction not being satisfied or waived; (ii) the occurrence of any event, change or other circumstances that could give rise to the termination of the applicable transaction agreements; (iii) the risk that there may be a material adverse change with respect to the financial position, performance, operations or prospects of the Listco, Amber DWM or the combined entity; (iv) risks related to disruption of management time from ongoing business operations due to the proposed transaction; (v) the risk that any announcements relating to the proposed transaction could have adverse effects on the market price of the Listco's securities; (vi) the risk that the proposed transaction and its announcement could have an adverse effect on the ability of Amber DWM or the combined entity to retain customers and retain and hire key personnel and maintain relationships with their suppliers and customers and on their operating results and businesses generally; (vii) any changes in the business or operating prospects of Amber DWM and the combined entity or their businesses; (viii) changes in applicable laws and regulations; and (ix) risks relating to Amber DWM's and the combined company's ability to enhance their services and products, execute their business strategy, expand their customer base and maintain stable relationship with their business partners. A further list and description of risks and uncertainties can be found in the proxy statement that will be filed with the SEC by the Listco in connection with the proposed transactions, and other documents that the parties may file or furnish with the SEC, which you are encouraged to read. Should one or more of these risks or uncertainties materialize, or should underlying assumptions prove incorrect, actual results may vary materially from those indicated or anticipated by such forward-looking statements. Accordingly, you are cautioned not to place undue reliance on these forward-looking statements. Forward-looking statements relate only to the date they were made, and the Listco, Amber DWM and their respective subsidiaries and affiliates undertake no obligation to update forward-looking statements to reflect events or circumstances after the date they were made except as required by law or applicable regulation. No Offer or Solicitation This press release is not a proxy statement or solicitation of a proxy, consent or authorization with respect to any securities or in respect of the transactions described above and shall not constitute an offer to sell or a solicitation of an offer to buy the securities of Amber DWM, the Listco or the combined company, nor shall there be any sale of any such securities in any state or jurisdiction in which such offer, solicitation, or sale would be unlawful prior to registration or qualification under the securities laws of such state or jurisdiction. No offering of securities shall be made except by means of a prospectus meeting the requirements of Section 10 of the Securities Act of 1933, as amended, or an exemption therefrom. Participants in the Solicitation The Listco, Amber DWM and their respective directors and executive officers may also be deemed to be participants in the solicitation of proxies from the shareholders of the Listco in connection with the proposed transaction. A list of the names of such directors and executive officers and information regarding their interests in the proposed transaction will be included in the proxy statement pertaining to the proposed transaction when it becomes available for the proposed transaction. Additional Information and Where to Find It The Listco will file with the SEC and mail to its shareholders a proxy statement in connection with the proposed transaction. Investors and securityholders are urged to read the proxy statement when it becomes available because it will contain important information regarding the proposed arrangement. You may access the proxy statement (when available) and other related documents filed by the Listco with the SEC at the SEC's website at www.sec.gov . You also may obtain the proxy statement (when it is available) and other documents filed by the Listco with the SEC relating to the proposed arrangement for free by accessing the Listco's website at ir.i-click.com . View original content to download multimedia: https://www.prnewswire.com/news-releases/amber-groups-subsidiary-amber-dwm-holding-limited-and-nasdaq-listed-iclick-interactive-asia-group-limited-enter-into-a-definitive-merger-agreement-302319082.html SOURCE Amber GroupMumbai, Nov 30 (PTI) Pearl Academy, a unit of the Creative Arts Education Society (CAES), on Saturday said it has collaborated with Tech Mahindra to set up the 'Makers Lab', which will serve as an innovation hub focused on Generative AI (GenAI), metaverse, and gaming. The lab will be set up in Bengaluru. The collaboration aims to empower students, faculty, and industry professionals to develop solutions in artificial intelligence (AI), metaverse, and immersive gaming experiences, Pearl Academy said in a statement. "By blending our design innovation with Tech Mahindra's technological prowess, we are shaping a future where creativity and technology seamlessly integrate to redefine industries. "The Makers Lab will provide our students with invaluable hands-on experience in emerging technologies, empowering them to reshape the creative landscape," Pearl Academy President Aditi Srivastava said. Pearl Academy also said its faculty will collaborate with Tech Mahindra's researchers to apply human-centred design principles to technology development. (This story has not been edited by THE WEEK and is auto-generated from PTI)None
- Previous: phlove vip login app
- Next: 26 phlove casino login