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ssbet77 com login Notation Labs Secures $2 Million Credit Facility to Accelerate Production of QwelTM, a Cutting-Edge Lead Detection and Prevention SystemGREENVILLE, S.C. (AP) — Pjay Smith Jr. scored 23 points as Furman beat Princeton 69-63 on Saturday. Smith also added eight rebounds and four steals for the Paladins (9-1). Garrett Hien scored 10 points while going 5 of 10 and 0 of 4 from the free-throw line and added seven rebounds. Nick Anderson shot 3 for 9 from beyond the arc to finish with nine points. The Tigers (7-4) were led by Xaivian Lee, who posted 16 points, seven rebounds and five assists. Princeton also got 13 points and four assists from Dalen Davis. Caden Pierce also had 11 points and four steals. NEXT UP Up next for Furman is a Saturday matchup with South Carolina State at home, and Princeton hosts Monmouth on Tuesday. The Associated Press created this story using technology provided by Data Skrive and data from Sportradar .

Brock Purdy will miss Sunday's game for the 49ers with a shoulder injury



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St. Thomas police officers were called to attend a south end restaurant for an assault Friday. Police learned that two individuals were having dinner when a dispute between them turned physical, resulting in a woman assaulting a man with cutlery. No injuries were sustained. According to police, the woman was on conditions not to be around the man. A 47-year-old female was arrested and charged with assault with a weapon and two counts of fail to comply with probation. The male has also been charged with party to the offence and a summons has been requested. Shopping Trends The Shopping Trends team is independent of the journalists at CTV News. We may earn a commission when you use our links to shop. Read about us. Editor's Picks Here Are All The Best Amazon Boxing Day Deals You Can Find On Beauty Products In Canada These Walking Pads Will Help You Get 10,000 Steps Every Day (And They're On Sale In The Name Of Boxing Day) 10 Family Calendars And Planners That'll Help You Keep Track Of Everything In The New Year Home If You're Headed Somewhere Warm On Vacation, Don't Forget To Pack These 16 Things Our Guide To The Best Snow Shovels In Canada In 2024 (And Where To Get Them) 14 Of The Best Home Security Devices You Can Find Online Right Now (And They've Got The Reviews To Prove It) Gifts The Clock Is Ticking — Shop These 25 Last-Minute Amazon Prime Gifts Now If You Have An Amazon Prime Account, These 70+ Crowd-Pleasing Gifts Will Still Arrive Before Christmas If You Have An Amazon Prime Account, These 50 Brilliant Stocking Stuffers Will Still Arrive Before Christmas Beauty 20 Products Your Dry, Dehydrated Skin Will Thank You For Ordering 14 Hydrating Face Masks That’ll Save Your Skin This December 12 Budget-Friendly Products To Add To Your Winter Skincare Routine Deals 11 Bestselling Coffee Makers And Espresso Machines You Can Get On Sale Right Now Don’t Walk, Run! These LEGO Kits Are On Sale For Boxing Day 2024 The Waterpik Advanced Water Flosser Will Make Cleaning Your Teeth So Much Easier — And It's 41% Off For Boxing Day London Top Stories St. Thomas fraud victim loses nearly $100K to job scam Ending the year with above seasonal temperatures Assault at restaurant leads to charges in St. Thomas Despite best efforts, Cowan and Knights couldn't help Canada past Latvia at World Juniors Power restored in east London following outage, police investigating crash Two seriously hurt in passenger vehicle collision with horse drawn carriage Wortley Village business pillar to rise again as 'homage to what it was' 'I really hope that our connection is not complete': Could South Bruce be home to a different nuclear waste project? CTVNews.ca Top Stories Calgary Skyview MP George Chahal joins growing chorus of Liberals calling for Trudeau to step down Calgary Liberal MP George Chahal has publicly released letters he sent to the Liberal caucus and president of the Liberal Party of Canada, calling on them to begin the process of moving on from Prime Minister Justin Trudeau. DEVELOPING | Delta, B.C., port terminals closed after 'machinery fire' Saturday morning A large fire at the port in Delta, B.C., sent a plume of smoke into the sky Saturday morning. Magnus Carlsen quits World Rapid and Blitz Championships after refusing to change out of jeans World No. 1 Magnus Carlsen quit the World Rapid Chess Championship on Friday after he refused to change out of the jeans he was wearing, according to the International Chess Federation (FIDE). If you're mentally struggling during the holidays, here’s how to cope For many people, celebrating New Year’s Day can include reflecting on a life well lived or a chance to start anew. But for some, the holiday may have dark undertones, according to a recent large study. Friend of Quebec man killed in Florida boat explosion says his sister also injured A childhood friend of the Quebec man killed in a Florida boat explosion earlier this week says one of the victim's sisters was among the other six passengers injured in the blast. Trudeau, Carney push back over Trump's ongoing 51st state comments Two senior members of the federal cabinet were in Florida Friday pushing Canada's new $1.3 billion border plan with members of Donald Trump's transition team, a day after Prime Minister Justin Trudeau himself appeared to finally push back at the president-elect over his social media posts about turning Canada into the 51st state. Beware the slithering scales: Monkeys fear snakeskin even when it's not on a snake, study suggests A new study suggests monkeys can identify snakes by their scales, and know to fear them, even when those scales aren't on a snake. What is known about a plane crash in Kazakhstan after Putin apologized for a 'tragic incident'? Russian President Vladimir Putin on Saturday apologized to his Azerbaijani counterpart for what he called a 'tragic incident' following the crash of an Azerbaijani airliner in Kazakhstan that killed 38 people, but stopped short of acknowledging that Moscow was responsible. G2 driver stopped going more than 100 km/h over the speed limit on Hwy. 401 in eastern Ontario A 17-year-old driver is facing charges after being caught speeding and driving dangerously on Highway 401 in eastern Ontario Friday evening, according to the Ontario Provincial Police (OPP). Kitchener Minor flooding possible with snow melt, rain on way: GRCA The Waterloo Region and the city of Guelph will be wrapping up 2024 with unusually warm weather over the weekend. Stretch of Kitchener road closed after gas leak at abandoned building Kitchener Fire is investigating after a "strange odor" was reported on Courtland Avenue East Saturday. Cambridge structure fire leads to road closure Emergency Services are on scene of a Cambridge structure fire Saturday morning. Barrie 43-quintillion combinations: Speedcubers solve Rubik's Cubes in record breaking times On Saturday, Barrie is testing the abilities of some of the fastest cube solvers from across the province and around the world. County Road 56 reopens following afternoon collision County Road 56 in Essa Township was closed for an afternoon collision. How winter donations can save lives at local cat shelter As the brisk weather settles in, staff at a local non-profit shelter in Barrie are seeing an influx of cats and kittens coming through their doors from all walks of life. Windsor Community partners in Windsor propose education campaign to veer people away from payday loans In a move aimed at combatting the financial strain caused by payday loans, the City of Windsor is considering the launch of a comprehensive education campaign to promote alternative financial options. Ex-boyfriend arrested for violating bail conditions Chatham-Kent police have made an arrest after a man allegedly violated his bail conditions. $15M plan to shift Sandpoint Beach away from hazardous drop-off heading to council A $15-million plan to relocate and revitalize Sandpoint Beach — shifting its swimming area away from hazardous waters and adding features like a splash pad and accessible playground — will go before Windsor city councillors at their first meeting of the new year. Northern Ontario Serious crash closes Hwy. 11 near North Bay A serious collision has closed Highway 11 between the Bay Truck Stop in North Bay and Highway 64 in Marten River. Calgary Skyview MP George Chahal joins growing chorus of Liberals calling for Trudeau to step down Calgary Liberal MP George Chahal has publicly released letters he sent to the Liberal caucus and president of the Liberal Party of Canada, calling on them to begin the process of moving on from Prime Minister Justin Trudeau. Five southern Ont. hunters fined $37K for moose hunt offences in northern Ont. A multi-year moose hunting investigation resulted in five people being convicted of moose hunting offences and fined a total of $37,000, plus $9,250 in victim surcharges. Sault Ste. Marie Man shot by officer after firing at police car near Thunder Bay: SIU Ontario's Special Investigations Unit is probing a shooting near Thunder Bay in which a man was shot and wounded by a police officer on Boxing Day. Alleged impaired driver crashes into police cruiser on Boxing Day While on general patrol in northwestern Ontario on Boxing Day, an Ontario Provincial Police officer’s vehicle was struck. Five southern Ont. hunters fined $37K for moose hunt offences in northern Ont. A multi-year moose hunting investigation resulted in five people being convicted of moose hunting offences and fined a total of $37,000, plus $9,250 in victim surcharges. Ottawa G2 driver stopped going more than 100 km/h over the speed limit on Hwy. 401 in eastern Ontario A 17-year-old driver is facing charges after being caught speeding and driving dangerously on Highway 401 in eastern Ontario Friday evening, according to the Ontario Provincial Police (OPP). Here's how you can watch CTV News at Six tonight during the NFL game With CTV broadcasting tonight's NFL game, CTV News at Six will be broadcasting live on our website and the CTV News App. FREEZING RAIN WARNING | Freezing rain warning in effect for Ottawa this Saturday Environment Canada says a freezing rain warning is in effect for Ottawa this Saturday. Toronto One person injured, suspect charged with arson following Etobicoke apartment fire A suspect has been charged with arson after a two-alarm fire at an Etobicoke apartment complex early Saturday morning left one person with injuries. Motorcyclist dead after 2-vehicle crash in Stouffville, Ont.: police A 21-year-old man is dead following a two-vehicle crash in Stouffville, Ont. early Saturday morning. Trudeau, Carney push back over Trump's ongoing 51st state comments Two senior members of the federal cabinet were in Florida Friday pushing Canada's new $1.3 billion border plan with members of Donald Trump's transition team, a day after Prime Minister Justin Trudeau himself appeared to finally push back at the president-elect over his social media posts about turning Canada into the 51st state. Montreal Friend of Quebec man killed in Florida boat explosion says his sister also injured A childhood friend of the Quebec man killed in a Florida boat explosion earlier this week says one of the victim's sisters was among the other six passengers injured in the blast. Cyprus-flagged ship MV MACCOA remains stuck near Verchères The MV MACCOA, a cargo ship registered in Cyprus, that ran aground on Christmas Eve in the St. Lawrence River near Verchères, Que., was still trapped on Saturday, after the Friday’s attempt to refloat it failed. Here are the changes coming to Quebec in 2025 With the new year just days away, here is a look at the changes that are in store for Quebecers in 2025. Atlantic One dead in two-vehicle collision in Sackville, N.B. One person has died following a two-vehicle collision in Sackville, N.B., Friday. 'Nobody should have to go through that': N.B. family grieving father, daughter killed in crash A New Brunswick family is grieving the loss of a father and daughter in a crash. No one injured after vehicle crashes into Shoppers Drug Mart: N.S. RCMP RCMP is investigating after a vehicle crashed into a Shoppers Drug Mart in Lower Sackville, N.S. on Saturday. Winnipeg Experts, province urge caution over ice conditions after man dies in Hanover The province, along with outdoor enthusiasts, are urging people to use caution near frozen bodies of water after a man died when his skid steer loader fell through the ice. The most-read stories on CTV Winnipeg in 2024 Historic events, community pride and significant losses dominated headlines in Manitoba in 2024. Here’s a list of the most-read stories of each month of 2024 on CTV News Winnipeg. No serious injuries in apartment fire on Henderson Highway No one was hospitalized after a blaze broke out in a three-storey apartment building Saturday morning. Calgary Calgary Skyview MP George Chahal joins growing chorus of Liberals calling for Trudeau to step down Calgary Liberal MP George Chahal has publicly released letters he sent to the Liberal caucus and president of the Liberal Party of Canada, calling on them to begin the process of moving on from Prime Minister Justin Trudeau. Calgary Boxing Day crash victim identified, mother and sister still in hospital A nine-year-old girl has died in hospital after the vehicle she was in was struck by a driver in a stolen vehicle fleeing from police. Family and friends grieve death of 36-year-old Lethbridge man in motorcycle crash Family members and friends are mourning the loss of a 36-year-old Lethbridge man killed in motorcycle crash just two days before Christmas. Edmonton Edmonton street photographer captures moments and people one frame at a time A local photographer who is passionate about capturing moments in one-hundredth of a second embraced many styles of his trade before landing on one which truly represents his mantra: street photography. 2 vehicles fall through ice at Sylvan Lake, promoting police warning RCMP issued a warning Saturday after two vehicles fell through the ice on Sylvan Lake. Physical therapy is 'the best-kept secret in health care' If you think physical therapy is only about rehabilitation after surgery or recovering from an accident, think again. For the vast majority, seeing a physical therapist should be about prevention, routine assessment and staying well. Regina 'A great holiday memory': Echo Valley Provincial Park gets plenty of visitors at Skate the Park launch Families and groups of friends made use of the good weather as the new season of Skate the Park got underway at Echo Valley Provincial Park. Moose Jaw Police Service asks public to help locate 89-year-old man The Moose Jaw Police Service (MJPS) is asking the public for help in locating an 89-year-old Moose Jaw resident who was last seen on Dec. 25, 2024. Regina police chief says new initiatives to enhance community safety will come in 2025 Looking back after one year in his new role as the chief of the Regina Police Service, Farooq Hassan Sheikh is highlighting challenges the city faces, what has worked during his tenure and what can be done to improve policing in 2025. Saskatoon The thrill is gone from Boxing Week shopping, Saskatoon residents say Christmas has come and gone for most people, but the shopping hype continues as some get out of the house to take in the post-Christmas scene. Police made two arrests following a shooting in Saskatoon A swift response from Saskatoon police led to the arrest of a man and woman following a reported shooting Friday afternoon. Saskatoon fire crews battle house fire Saskatoon firefighters responded to a house fire on the 100 block of Klassen Crescent Friday afternoon. Vancouver DEVELOPING | Delta, B.C., port terminals closed after 'machinery fire' Saturday morning A large fire at the port in Delta, B.C., sent a plume of smoke into the sky Saturday morning. New Canadians, non-traditional demographics boost minor hockey uptake in B.C. Participation in hockey in British Columbia was struggling in 2021 — the pandemic had dealt a heavy blow to player registrations, and numbers had already been flagging before COVID-19 arrived. Vancouver artist and HIV advocate Joe Average dies at 67 Renowned Vancouver artist Joe Average, whose colourful work adorns murals and banners around the city, died at age 67 Tuesday, according to family and friends. Vancouver Island New Canadians, non-traditional demographics boost minor hockey uptake in B.C. Participation in hockey in British Columbia was struggling in 2021 — the pandemic had dealt a heavy blow to player registrations, and numbers had already been flagging before COVID-19 arrived. 'We're sending a clear message': B.C. prepares for home flipping tax amid criticism Next week, when the calendars turn to 2025, the provincial government will begin imposing a 20-per-cent tax on all profits if a home is sold within a year of purchasing it. Former B.C. lawyer disbarred for 2nd time over sexual harassment A former lawyer who was convicted of sexual assault in 2020 and disbarred last year has been handed a second disbarment for sexual harassment of a different client. Stay ConnectedOn Monday night, the entire Simpsons universe gets to experience it in a way not many could have imagined. The prime-time matchup between the Cincinnati Bengals and Dallas Cowboys will also take place at Springfield’s Atoms Stadium as part of “The Simpsons Funday Football” alternate broadcast. The altcast will be streamed on ESPN+, Disney+, and NFL+ (on mobile devices). ESPN and ABC have the main broadcast, while ESPN2 will carry the final “ManningCast” of the regular season. The replay will be available on Disney+ for 30 days. Globally, more than 145 countries will have access to either live or on replay. “We’re such huge football fans, and the Simpsons audience and the football audience, I feel, are like the same audience of just American families and football. And the Simpsons are so much a part of the DNA of the American family and culture that for us to, like, mush them together in this crazy video game, it’s so fun,” said Matt Selman, executive producer of “The Simpsons.” While the game is the focal point, the alternate broadcast, in some ways, will resemble a three-hour episode of “The Simpsons.” It starts with Homer eating too many hot dogs and having a dream while watching football. Homer joins the Cowboys in the dream while Bart teams up with the Bengals. Lisa and Marge will be sideline reporters. “That’s the beginning of the story, and the story continues through the entire game until Homer wakes up from his dream at the end of the game. It is like a complete story, and the NFL game will happen in between. It’s just going to be an amazing presentation with tons of surprises,” said Michael “Spike” Szykowny, ESPN’s VP of edit and animation. This is the second year ESPN has done an alternate broadcast for an NFL game. It used the characters from “Toy Story” for last year’s Sunday morning game from London between the Atlanta Falcons and Jacksonville Jaguars. “The Simpsons” has featured many sports-themed episodes during its 35 seasons. Even though “Homer at the Bat” remains the consensus favorite sports episode for many Simpsons fans, there have been football ones such as “Bart Star” and “Lisa The Greek.” There also was a Super Bowl-themed one after Fox’s broadcast of Super Bowl 33 between Denver and Atlanta in 1999. Even though “The Simpsons” remains a staple on Fox’s prime-time schedule, it is part of the Disney family after their acquisition of 20th Century Fox in 2019. All 35 seasons are on Disney+. The show’s creators have worked with ESPN and the NFL to make sure the look and sound is definitely Simpsonsesque. The theme song is a mash-up of “The Simpsons” opening and “Monday Night Football’s” iconic “Heavy Action.” There have also been pre-recorded skits and bits to use during the broadcast featuring Simpson’s legendary voices Hank Azaria, Nancy Cartwright, Dan Castellaneta, Julie Kavner, and Yeardley Smith. The telecast will be entirely animated, with the players’ movements in sync with what is happening in real-time on the field. That is done through player-tracking data enabled by the NFL’s Next Gen Stats system and Sony’s Beyond Sports Technology. While Next Gen Stats tracks where players are on the field with a tracking chip in the shoulder pads, there is skeletal data tracking and limb tracking data — which uses 29 points per player — to get closer to the player’s movements. The other data tracking will allow Beyond Sports and Disney to add special characters to the game. For example, there might be a play where Lisa catches the ball and goes 30 yards instead of Cincinnati’s Tee Higgins. “Lisa is much smaller than the rest of the players. So, in real life, the ball would go over her head, but now, with data processing, we can take the ball and make it go exactly into her hands. So for the viewer, it still looks believable, and it all makes sense,” said Beyond Sports co-founder Nicolaas Westerhof. The other major challenge is making “The Simpsons” two-dimensional cartoon characters into 3-D simulations. Szykowny and his team worked to make that a reality over the past couple of months. “That’s a big leap of faith for them to say, hey, we trust you to make our characters 3-D and work with it. Our ESPN creative studio team has done a wonderful job,” Szykowny said. Lisa, Krusty, Nelson, Milhouse and Ralph will be with Bart and the Bengals; while Carl, Barney, Lenny and Moe join up with with Homer and the Cowboys. The broadcast will also feature ESPN personalities Stephen A. Smith, Peyton Manning and Eli Manning. ESPN’s Drew Carter, Mina Kimes and Dan Orlovsky will call the game from Bristol, Connecticut, and also be animated. They will wear Meta Quest Pro headsets to experience the game from Springfield using VR technology. For Kimes, being part of the broadcast and being an animated Simpsons character is a dream come true. She is a massive fan of the show and has a framed photo of Lisa Simpson — who she said is a personal hero and icon — as part of her backdrop when she makes appearances on ESPN NFL shows from her home in Los Angeles. “I didn’t have any input, and I didn’t see anything beforehand, so I wasn’t sure if it would look like me, but it kind of does, which is very funny,” said Kimes, who drew Simpsons characters when she was a kid. “To see the actual staff turn me into one was a dream.” Even though the Bengals (4-8) and Cowboys (5-7) have struggled this season, Selman thinks both teams have personalities that appeal to “The Simpsons” universe. “We were just so lucky also that the Cowboys are sort of like a Homer Simpson-type team, American team, and Mike McCarthy might be a Homer-type guy, one might imagine,” he said. ”And then you have Joe Burrow on the other side who is a cool young, spiky-haired, blonde bad boy -- he’s like Bart. And that fits our character archetypes so perfectly. “If Homer is mad at Bart and has a hot dog dream while watching ’Monday Night Football’, and then it’s basically McCarthy versus Burrow, Homer versus Bart, and that’s the simple father versus son strangling — Homer strangling Bart dynamic that has been part of the show for 35 years. I don’t know if that would have worked as well if it was like Titans versus Jacksonville. We would have found something. We would have made it work.” AP NFL: https://apnews.com/hub/nfl

PIAA wants to recruit more women to officiate football gamesThe International Criminal Court issued arrest warrants on Thursday for Israeli Prime Minister Benjamin Netanyahu, his former defense minister and a Hamas military leader, accusing them of war crimes and crimes against humanity. The announcement came as health officials in the Gaza Strip said the death toll from the 13-month-old war between Israel and Hamas has surpassed 44,000. The warrant marked the first time that a sitting leader of a major Western ally has been accused of war crimes and crimes against humanity by a global court of justice. The ICC panel said there were reasonable grounds to believe that both Netanyahu and his ex-defense minister bear responsibility for the war crime of starvation and the crimes against humanity of murder, persecution and other inhumane acts. Israel’s war has caused heavy destruction across Gaza, decimated parts of the territory and driven almost the entire population of 2.3 million people from their homes, leaving most dependent on aid to survive. Israel launched its war in Gaza after Hamas-led militants stormed into southern Israel on Oct. 7, 2023, killing some 1,200 people, mostly civilians, and abducting another 250 . Around 100 hostages are still inside Gaza, at least a third of whom are believed to be dead. Here’s the Latest: WASHINGTON — The White House fundamentally rejects the International Criminal Court’s decision to issue arrest warrants for senior Israeli officials, press secretary Karine Jean-Pierre said Thursday. She said the Biden administration was “deeply concerned by the prosecutor’s rush to seek arrest warrants and the troubling process errors that led to this decision.” The Biden administration has increased its warnings and appeals to Israeli Prime Minister Benjamin Netanyahu to do more to spare civilians in airstrikes and other attacks, and to allow more aid to reach Gaza. However, a 30-day Biden administration deadline came and went earlier this month for Israel to meet specific U.S. targets to improve its treatment of Palestinian civilians in Gaza trapped in the war. U.S. demands included that Israel lift a near-total ban on delivery of aid to hard-hit north Gaza for starving civilians there. KHAN YOUNIS, Gaza Strip — The three children were playing outside a cluster of tents housing displaced people in the Gaza Strip when an Israeli airstrike killed them, along with six other people. It’s become a grim, near-daily ritual more than 13 months into the Israel-Hamas war, which local health authorities said Thursday has killed over 44,000 Palestinians. Israel carries out frequent strikes against what it says are militants hiding in civilian areas, and women and children are nearly always among the dead. Wednesday’s strike killed Hamza al-Qadi, 7, his brother Abdulaziz, 5, and their sister Laila, 4, in a tent camp in the southern city of Khan Younis. Areej al-Qadi, their mother, says they were playing outside when they were killed. “All that’s left of them are their notebooks, their books and a blood-stained jacket,” she said as she broke into tears. “They were children who did nothing.” The Israeli military did not respond to a request for comment on the strike. Gaza’s Health Ministry said Thursday that 44,056 Palestinians have been killed and 104,268 wounded since the start of the war, which was ignited by Hamas’ Oct. 7 attack into Israel. Palestinian militants killed some 1,200 people that day, mostly civilians, and abducted around 250 people. The Health Ministry does not say how many of those killed in Gaza were fighters but says women and children make up more than half the fatalities. Israel, which rarely comments on individual strikes, says it has killed over 17,000 militants, without providing evidence. Hours after the ministry announced the latest toll, the International Criminal Court issued arrest warrants against Israeli Prime Minister Benjamin Netanyahu, his former defense minister and a Hamas military leader. Mahmoud bin Hassan, the children’s father, said he buried them on Thursday. He asked when the international community would take action to stop the war. “When the entire Palestinian population has been killed?” he said. NEW YORK — Human Rights Watch applauded the International Criminal Court's arrest warrants issued Thursday against both Israeli and Hamas officials. The warrants “break through the perception that certain individuals are beyond the reach of the law,” the associate international justice director at Human Rights Watch, Balkees Jarrah, said in a statement. The New York-based rights group earlier this month released a report saying Israel has committed war crimes and crimes against humanity in the Gaza Strip, including massive forced displacements that amount to ethnic cleansing. JERUSALEM — Israeli prosecutors have charged a former aide to Prime Minister Benjamin Netanyahu with leaking classified documents to international media, apparently to protect the Israeli leader from criticism as a hostage deal was collapsing. Eli Feldstein, a former media adviser to Netanyahu, was charged Thursday with leaking classified information with the intent of harming state security and obstruction of justice. The leaked documents are said to have formed the basis of a widely discredited article in the London-based Jewish Chronicle — which was later withdrawn — suggesting Hamas planned to spirit hostages out of Gaza through Egypt, and an article in Germany’s Bild newspaper that said Hamas was drawing out the hostage talks as a form of psychological warfare on Israel. Critics say the leaks were aimed at giving Netanyahu political cover as the case-fire talks ground to a halt. Some have accused Netanyahu of resisting a deal in to preserve his governing coalition, which includes hard-line members who have threatened to bring down the government if he makes concessions to Hamas. The leaks came at a time of public uproar over the deaths of six hostages who were killed by their Hamas captors as Israeli soldiers were closing in. The indictment said the leaks were meant “to create media influence on the public discourse in Israel in regards to the handling of the hostage situation, after the news of the murder of six hostages.” The indictment identified two other Netanyahu aides as being connected to the scheme, but only Feldstein and an unidentified reservist in Israeli military intelligence were charged. Netanyahu, who denies the accusations, has not been identified as a suspect in the burgeoning investigation. Israeli media say if convicted, Feldstein could potentially face life in prison. JERUSALEM -- The Israeli military has launched an investigation into the death of a 70-year-old Israeli man who entered Lebanon with Israeli forces and was killed in a Hezbollah ambush. Investigators are trying to determine, among other things, who allowed Zeev Erlich into the combat zone with the forces and why he was permitted to enter. According to Israeli media reports, Erlich was not on active duty when he was shot, but was wearing a military uniform and had a weapon. The army said he was a reservist with the rank of major and identified him as a “fallen soldier” when it announced his death. Erlich was a well-known West Bank settler and researcher of Jewish history. Media reports said Erlich was permitted to enter Lebanon to explore a local archaeological site. The army said a 20-year-old soldier was killed in the same incident, while an officer was badly wounded. The army announced Thursday that the chief of staff, Lt. Gen. Herzi Halevi, has appointed a team of experts “to examine and strengthen operational discipline and military culture” following the incident. It said its commander for northern Israel, Maj. Gen. Ori Gordin, would launch a separate “command inquiry,” while Israeli military police conduct a separate probe. Such investigations can lead to criminal charges. BEIRUT — At least 29 people were killed Thursday in Israeli strikes on different towns and villages across Lebanon, according to Lebanon’s Health Ministry and state-run media. In eastern Lebanon, Israeli airstrikes killed 26 people in six different towns in Baalbek province, the health ministry and the National News Agency said. In Tyre province, southern Lebanon, three people were killed in an Israeli strike, the health ministry said. The health ministry Wednesday said that over 3,550 people have been killed in the 13-month war between Hezbollah and Israel, the majority following Israel’s escalation in late September. The European Union's foreign policy chief has underlined that the arrest warrants issued by the International Criminal Court against Israeli Prime Minister Benjamin Netanyahu and Hamas officials are a legal and not political matter, and that they are binding on all 27 EU member countries and other signatories to the ICC to implement. “The tragedy in Gaza has to stop," Josep Borrell told reporters during a visit to Jordan. “It is not a political decision. It is the decision of an international court of justice, and the decision of the court has to be respected, and implemented.” “This decision is a binding decision on all state parties of the court, which include all members of the European Union," he added. ANKARA — Turkish President Recep Tayyip Erdogan’s ruling partyhas welcomed the decision by the International Criminal Court to issue arrest warrants against Israeli Prime Minister Benjamn Netanyahu and former Defense Minister Yoav Gallant, calling it a judgement made for the sake of “humanity.” Omer Celik, spokesman for the Erdogan’s party, said on the social media platform X that Netanyahu and Gallant would “eventually be held accountable for genocide.” Celik also criticised Israeli officials who described the ICC decision as antisemitic. Turkey is among the most vocal critics of Israel’s military actions in Gaza and has submitted a formal request to join a genocide case that South Africa has filed against Israel at the U.N.’s International Court of Justice. Dutch foreign minister Caspar Veldkamp, whose country hosts the International Criminal Court, has confirmed The Netherlands would arrest Israeli Prime Minister Benjamin Netanyahu if he arrived on Dutch soil. “The line from the government is clear. We are obliged to cooperate with the ICC ... we abide 100% by the Rome Statute,” he said in response to a question in parliament Thursday. Other European officials were more cautious. In France, a spokesman for the Foreign Ministry said he supported the International Criminal Court's prosecutor but declined to comment when asked more specifically if France would arrest Netanyahu if he were to step on French soil. “Today, combating impunity is our priority. We ratified the ICC Statute in 2000 and have consistently supported the court’s actions. Our response will align with these principles,” Christophe Lemoine told reporters at a press conference. Lemoine added that the warrants were “a complex legal issue ... It’s a situation that requires a lot of legal precautions.” In Italy, the foreign and justice ministries didn’t immediately respond to emails seeking comment about whether Italy, an ICC member which hosted the Rome conference that gave birth to the court, would honor the arrest warrant. Premier Giorgia Meloni hosted Prime Minister Benjamin Netanyahu in March 2023 and has strongly supported Israel since Oct. 7, while providing humanitarian aid for Palestinians in Gaza. JERUSALEM — Israel’s mostly ceremonial president, Isaac Herzog, has called the International Criminal Court's arrest warrants against Prime Minister Benjamin Netanyahu “a dark day for justice. A dark day for humanity.” In a post on X, he said the international court “has chosen the side of terror and evil over democracy and freedom, and turned the very system of justice into a human shield for Hamas’ crimes against humanity." Israel Katz, Israel’s new defense minister, said the decision was “a moral disgrace, entirely tainted by antisemitism, and drags the international judicial system to an unprecedented low.” He said it “serves Iran, the head of the snake, and its proxies.” Benny Gantz, a retired general and political rival to Netanyahu, also condemned the decision, saying it showed “moral blindness” and was a “shameful stain of historic proportion that will never be forgotten.” Hamas has welcomed the decision by the International Criminal Court to issue warrants against Israeli President Benjamin Netanyahu and his former defense minister Yoav Gallant, calling it an “important and historic precedent” after what it said was decades of injustice at the hands of a “fascist occupation.” The statement did not refer to the warrants issued for the militant group’s own leaders. Hamas called on all nations to “cooperate with the court in bringing the Zionist war criminals, Netanyahu and Gallant, to justice, and to work immediately to stop the crimes of genocide against innocent civilians in the Gaza Strip.” DEIR AL-BALAH, The Gaza Strip — Bakeries have reopened in the central Gaza Strip after being closed for several days because of flour shortages. The shortages appear to have been linked to the looting of nearly 100 truckloads of aid by armed men in southern Gaza last weekend. Associated Press footage showed a crowd of hundreds pushing and shouting outside a bakery in the central city of Deir al-Balah on Thursday. The day before the reopening, the price of a bag of 15 loaves of pita bread had climbed above $13. “In my house, there is not a morsel of bread, and the children are hungry,” said Sultan Abu Sultan, who was displaced from northern Gaza during the war. The amount of aid entering Gaza plunged in October as Israel launched a major offensive in the isolated north, where experts say famine may be underway . Hunger is widespread across the territory, even in central Gaza where aid groups have more access. Humanitarian organizations say Israeli restrictions, ongoing fighting and the breakdown of law and order make it difficult to deliver assistance. Israel’s offensive, launched after Hamas’ October 2023 attack, has displaced around 90% of Gaza’s population of 2.3 million people. Hundreds of thousands are crammed into tent camps with little in the way of public services and are reliant on international food aid. NICOSIA — The president of Cyprus says the European Union must play a bigger role in the Middle East as it can no longer stand by as an observer. President Nikos Christodoulides said the 27-member bloc needs to establish closer ties with countries that bolster regional stability like Egypt, Jordan and the Gulf states. “The conflict in the Middle East is taking place on the EU’s doorstep, in an area of vital interest to the bloc’s interests, where any escalation or regional spillover will have significant consequences on its security and stability,” Christodoulides told an Economist conference in the Cypriot capital. Christodoulides said EU member Cyprus for years has tried to get this message across to Brussels. The island nation earlier this year was the staging ground for a maritime corridor delivering some 20,000 tons of humanitarian aid to Gaza. The EU is wracked by members’ divisions over how peace should come about in the Middle East THE HAGUE — The International Criminal Court issued arrest warrants on Thursday for Israeli Prime Minister Benjamin Netanyahu, his former defense minister and Hamas officials, accusing them of war crimes and crimes against humanity over the war in Gaza and the October 2023 attacks that triggered Israel’s offensive in the Palestinian territory. The decision turns Netanyahu and the others into internationally wanted suspects and is likely to further isolate them and complicate efforts to negotiate a cease-fire to end the 13-month conflict. But its practical implications could be limited since Israel and its major ally, the United States, are not members of the court and several of the Hamas officials have been subsequently killed in the conflict. Netanyahu and other Israeli leaders have previously condemned ICC Chief Prosecutor Karim Khan’s request for the warrants as disgraceful and antisemitic. U.S. President Joe Biden also blasted the prosecutor and expressed support for Israel’s right to defend itself against Hamas. Hamas also slammed the request. The death toll in the Gaza Strip from the 13-month-old war between Israel and Hamas has surpassed 44,000, local health officials said Thursday. The Gaza Health Ministry does not distinguish between civilians and combatants in its count, but it has said that more than half of the fatalities are women and children. The Israeli military says it has killed over 17,000 militants, without providing evidence. The Health Ministry said 44,056 people have been killed and 104,268 wounded since the start of the war. It has said the real toll is higher because thousands of bodies are buried under rubble or in areas that medics cannot access. The war began when Hamas-led militants stormed into southern Israel on Oct. 7, 2023, killing some 1,200 people, mostly civilians, and abducting another 250 . Around 100 hostages are still inside Gaza, at least a third of whom are believed to be dead. Most of the rest were released during a cease-fire last year. Around 90% of Gaza's population of 2.3 million people have been displaced, often multiple times, and hundreds of thousands are living in squalid tent camps with little food, water or basic services. Israel says it tries to avoid harming civilians and blames their deaths on Hamas because the militants operate in residential areas, where they have built tunnels, rocket launchers and other military infrastructure. JERUSALEM — A rocket fired from Lebanon killed a man and wounded two others in northern Israel on Thursday, according to the Magen David Adom rescue service. The service said paramedics found the body of the man in his 30s near a playground in the town of Nahariya, near the border with Lebanon, after a rocket attack on Thursday. Israel meanwhile struck targets in southern Lebanon and several buildings south of Beirut, the Lebanese capital, after warning people to evacuate.

The long sports-filled Thanksgiving weekend is a time when many Americans enjoy gathering with friends and family for good food, good company and hopefully not too much political conversation. Also on the menu — all the NFL and college sports you can handle. Here's a roadmap to one of the biggest sports weekends of the year, with a look at marquee games over the holiday and how to watch. All times are in EST. All odds are by BetMGM Sportsbook. What to watch Thursday • NFL: There is a triple-header lined up for pro football fans. Chicago at Detroit, 12:30 p.m., CBS: Rookie quarterback Caleb Williams and the Bears go against the Lions, who are one of the favorites to reach the Super Bowl in February. Lions favored by 10. New York at Dallas, 4:30 p.m., Fox: The Giants and Cowboys are both suffering through miserable seasons and are now using backup quarterbacks for different reasons. But if Dallas can figure out a way to win, it will still be on the fringe of the playoff race. Cowboys favored by 3 1/2. Miami at Green Bay, 8:20 p.m., NBC/Peacock: The Packers stumbled slightly out of the gate but have won six of their past seven games. They'll need a win against Miami to try to keep pace in the NFC North. Packers favored by 3. • College Football: Memphis at No. 18 Tulane, 7:30 p.m., ESPN. If college football is your jam, this is a good warmup for a big weekend. The Tigers try to ruin the Green Wave’s perfect record in the American Athletic Conference. Tulane is favored by 14. Kansas City Chiefs quarterback Patrick Mahomes works in the pocket against the Carolina Panthers during the first half of Sunday's game in Charlotte, N.C. What to watch Friday • NFL: A rare Friday showdown features the league-leading Chiefs. Las Vegas at Kansas City, 3 p.m. Prime Video: The Chiefs and quarterback Patrick Mahomes are 12-point favorites over the Raiders. • College Basketball: Some of the top programs meet in holiday tournaments around the country. Battle 4 Atlantis championship, 5:30 p.m., ESPN: One of the premier early season tournaments, the eight-team field includes No. 3 Gonzaga, No. 14 Indiana and No. 24 Arizona. Rady Children's Invitational, 6 p.m., Fox: It's the championship game for a four-team field that includes No. 13 Purdue and No. 23 Mississippi. • College Football: There is a full slate of college games to dig into. Oregon State at No. 11 Boise State, noon, Fox: The Broncos try to stay in the College Football Playoff hunt when they host the Beavers. Boise State favored by 19 1/2. Oklahoma State at No. 23 Colorado, noon, ABC: The Buffaloes and Coach Prime are still in the hunt for the Big 12 championship game when they host the Cowboys. Colorado favored by 16 1/2. Georgia Tech at No. 6 Georgia, 7:30 p.m., ABC: The Bulldogs are on pace for a spot in the CFP but host what could be a tricky game against rival Georgia Tech. Georgia favored by 19 1/2. • NBA. After taking Thanksgiving off, pro basketball returns. Oklahoma City at Los Angeles Lakers, 10 p.m., ESPN: The Thunder look like one of the best teams in the NBA's Western Conference. They'll host Anthony Davis, LeBron James and the Lakers. Los Angeles Lakers forward LeBron James dunks during the first half of a Nov. 23 game against the Denver Nuggets in Los Angeles. What to watch Saturday • College Football. There are more matchups with playoff implications. Michigan at No. 2 Ohio State, noon, Fox: The Wolverines are struggling one season after winning the national title. They could make their fan base a whole lot happier with an upset of the Buckeyes. Ohio State favored by 21. No. 7 Tennessee at Vanderbilt, noon, ABC: The Volunteers are a fairly big favorite and have dominated this series, but the Commodores have been a tough team this season and already have achieved a monumental upset over Alabama. Tennessee favored by 11. No. 16 South Carolina at No. 12 Clemson, noon, ESPN: The Palmetto State rivals are both hanging on the edge of the CFP playoff race. A win — particularly for Clemson — would go a long way toward clinching its spot in the field. Clemson favored by 2 1/2. No. 3 Texas at No. 20 Texas A&M, 7:30 p.m. ABC: The Aggies host their in-state rival for the first time since 2011 after the Longhorns joined the SEC. Texas favored by 5 1/2. Washington at No. 1 Oregon, 7:30 p.m., NBC: The top-ranked Ducks have been one of the nation’s best teams all season. They’ll face the Huskies, who would love a marquee win in coach Jedd Fisch’s first season. Oregon favored by 19 1/2. • NBA: A star-studded clash is part of the league's lineup. Golden State at Phoenix, 9 p.m., NBA TV: Steph Curry and the Warriors are set to face the Suns' Big Three of Kevin Durant, Devin Booker and Bradley Beal. What to watch Sunday • NFL: It's Sunday, that says it all. Pittsburgh at Cincinnati, 1 p.m., CBS: Joe Burrow is having a great season for the Bengals, who are struggling in other areas. They need a win to stay in the playoff race, hosting a Steelers team that's 8-3 and won five of their past six. Bengals favored by 3. Arizona at Minnesota, 1 p.m., Fox: The Cardinals are tied for the top of the NFC West while the Vikings are 9-2 and have been one of the biggest surprises of the season with journeyman Sam Darnold under center. Vikings favored by 3 1/2. Philadelphia at Baltimore, 4:25 p.m., CBS: Two of the league's most electric players will be on the field when Saquon Barkley and the Eagles travel to face Lamar Jackson and the Ravens. Ravens favored by 3. San Francisco at Buffalo, 8:20 p.m. NBC/Peacock: The 49ers try to get back to .500 against the Bills, who have won six straight. Bills favored by 7. • NBA. The best teams in the Eastern Conference meet in a statement game. Boston at Cleveland, 6 p.m., NBA TV: The defending champion Celtics travel to face the Cavs, who won their first 15 games to start the season. • Premier League: English soccer fans have a marquee matchup. Manchester City at Liverpool, 11 a.m., USA Network/Telemundo. The two top teams meet with Manchester City trying to shake off recent struggles. • Auto Racing: The F1 season nears its conclusion. F1 Qatar Grand Prix, 11 a.m., ESPN2 – It's the penultimate race of the season. Max Verstappen already has clinched his fourth consecutive season championship. Before the 2023 National Football League season started, it seemed inevitable that Bill Belichick would end his career as the winningest head coach in league history. He had won six Super Bowls with the New England Patriots and 298 regular-season games, plus 31 playoff games, across his career. Then the 2023 season happened. Belichick's Patriots finished 4-13, the franchise's worst record since 1992. At the end of the year, Belichick and New England owner Robert Kraft agreed to part ways. And now, during the 2024 season, Belichick is on the sideline. He's 26 wins from the #1 spot, a mark he'd reach in little more than two seasons if he maintained his .647 career winning percentage. Will he ascend the summit? It's hard to tell. Belichick would be 73 if he graced the sidelines next season—meaning he'd need to coach until at least 75 to break the all-time mark. Only one other NFL coach has ever helmed a team at age 73: Romeo Crennel in 2020 for the Houston Texans. With Belichick's pursuit of history stalled, it's worth glancing at the legends who have reached the pinnacle of coaching success. Who else stands among the 10 winningest coaches in NFL history? Stacker ranked the coaches with the most all-time regular-season wins using data from Pro Football Reference . These coaches have combined for 36 league championships, which represents 31.6% of all championships won throughout the history of pro football. To learn who made the list, keep reading. You may also like: Ranking the biggest NFL Draft busts of the last 30 years - Seasons coached: 23 - Years active: 1981-2003 - Record: 190-165-2 - Winning percentage: .535 - Championships: 0 Dan Reeves reached the Super Bowl four times—thrice with the Denver Broncos and once with the Atlanta Falcons—but never won the NFL's crown jewel. Still, he racked up nearly 200 wins across his 23-year career, including a stint in charge of the New York Giants, with whom he won Coach of the Year in 1993. In all his tenures, he quickly built contenders—the three clubs he coached were a combined 17-31 the year before Reeves joined and 28-20 in his first year. However, his career ended on a sour note as he was fired from a 3-10 Falcons team after Week 14 in 2003. - Seasons coached: 23 - Years active: 1969-91 - Record: 193-148-1 - Winning percentage: .566 - Championships: 4 Chuck Noll's Pittsburgh Steelers were synonymous with success in the 1970s. Behind his defense, known as the Steel Curtain, and offensive stars, including Terry Bradshaw, Franco Harris, and Lynn Swann, Noll led the squad to four Super Bowl victories from 1974 to 1979. Noll's Steelers remain the lone team to win four Super Bowls in six years, though Andy Reid and Kansas City could equal that mark if they win the Lombardi Trophy this season. Noll was elected to the Pro Football Hall of Fame in 1993, two years after retiring. His legacy of coaching success has carried on in Pittsburgh—the club has had only two coaches (Bill Cowher and Mike Tomlin) since Noll retired. - Seasons coached: 21 - Years active: 1984-98, 2001-06 - Record: 200-126-1 - Winning percentage: .613 - Championships: 0 As head coach of Cleveland, Kansas City, Washington, and San Diego, Marty Schottenheimer proved a successful leader during the regular season. Notably, he was named Coach of the Year after turning around his 4-12 Chargers team to a 12-4 record in 2004. His teams, however, struggled during the playoffs. Schottheimer went 5-13 in the postseason, and he never made it past the conference championship round. As such, the Pennsylvania-born skipper is the winningest NFL coach never to win a league championship. - Seasons coached: 25 - Years active: 1946-62, '68-75 - Record: 213-104-9 - Winning percentage: .672 - Championships: 7 The only coach on this list to pilot a college team, Paul Brown, reached the pro ranks after a three-year stint at Ohio State and two years with the Navy during World War II. He guided the Cleveland Browns—named after Brown, their first coach—to four straight titles in the fledgling All-America Football Conference. After the league folded, the ballclub moved to the NFL in 1950, and Cleveland continued its winning ways, with Brown leading the team to championships in '50, '54, and '55. He was fired in 1963 but returned in 1968 as the co-founder and coach of the Cincinnati Bengals. His other notable accomplishments include helping to invent the face mask and breaking pro football's color barrier . - Seasons coached: 33 - Years active: 1921-53 - Record: 226-132-22 - Winning percentage: .631 - Championships: 6 An early stalwart of the NFL, Curly Lambeau spent 29 years helming the Green Bay Packers before wrapping up his coaching career with two-year stints with the Chicago Cardinals and Washington. His Packers won titles across three decades, including the league's first three-peat from 1929-31. Notably, he experienced only one losing season during his first 27 years with Green Bay, cementing his legacy of consistent success. Born in Green Bay, Lambeau co-founded the Packers and played halfback on the team from 1919-29. He was elected to the Hall of Fame as a coach and owner in 1963, two years before his death. You may also like: Countries with the most active NFL players - Seasons coached: 29 - Years active: 1960-88 - Record: 250-162-6 - Winning percentage: .607 - Championships: 2 The first head coach of the Dallas Cowboys, Tom Landry held the position for his entire 29-year tenure as an NFL coach. The Cowboys were especially dominant in the 1970s when they made five Super Bowls and won the big game twice. Landry was known for coaching strong all-around squads and a unit that earned the nickname the "Doomsday Defense." Between 1966 and 1985, Landry and his Cowboys enjoyed 20 straight seasons with a winning record. He was elected to the Hall of Fame in 1990. - Seasons coached: 26 - Years active: 1999-present - Record: 267-145-1 - Winning percentage: .648 - Championships: 3 The only active coach in the top 10, Andy Reid has posted successful runs with both the Philadelphia Eagles and Kansas City. After reaching the Super Bowl once in 14 years with the Eagles, Reid ratcheted things up with K.C., winning three titles since 2019. As back-to-back defending champions, Reid and Co. are looking this season to become the first franchise to three-peat in the Super Bowl era and the third to do so in NFL history after the Packers of 1929-31 and '65-67. Time will tell if Reid and his offensive wizardry can lead Kansas City to that feat. - Seasons coached: 29 - Years active: 1991-95, 2000-23 - Record: 302-165 - Winning percentage: .647 - Championships: 6 The most successful head coach of the 21st century, Bill Belichick first coached the Cleveland Browns before taking over the New England Patriots in 2000. With the Pats, Belichick combined with quarterback Tom Brady to win six Super Bowls in 18 years. Belichick and New England split after last season when the Patriots went 4-13—the worst record of Belichick's career. His name has swirled around potential coaching openings , but nothing has come of it. Belichick has remained in the media spotlight with his regular slot on the "Monday Night Football" ManningCast. - Seasons coached: 40 - Years active: 1920-29, '33-42, '46-55, '58-67 - Record: 318-148-31 - Winning percentage: .682 - Championships: 6 George Halas was the founder and longtime owner of the Chicago Bears and coached the team across four separate stints. Nicknamed "Papa Bear," he built the ballclub into one of the NFL's premier franchises behind players such as Bronko Nagurski and Sid Luckman. Halas also played for the team, competing as a player-coach in the 1920s. The first coach to study opponents via game film, he was once a baseball player and even made 12 appearances as a member of the New York Yankees in 1919. He was inducted into the Hall of Fame in 1963 as both a coach and owner. - Seasons coached: 33 - Years active: 1963-95 - Record: 328-156-6 - Winning percentage: .677 - Championships: 2 The winningest head coach in NFL history is Don Shula, who first coached the Baltimore Colts (losing Super Bowl III to Joe Namath and the New York Jets) for seven years before leading the Miami Dolphins for 26 seasons. With the Fins, Shula won back-to-back Super Bowls in 1972 and 1973, a run that included a 17-0 season—the only perfect campaign in NFL history. He also coached quarterback great Dan Marino in the 1980s and '90s, but the pair made it to a Super Bowl just once. Shula was inducted into the Hall of Fame in 1997. Story editing by Mike Taylor. Copy editing by Robert Wickwire. Photo selection by Lacy Kerrick. You may also like: The 5 biggest upsets of the 2023-24 NFL regular season Be the first to know Get local news delivered to your inbox!Love Island's Chyna Mills reveals she's living on a BOAT with Strictly Come Dancing fiancé Neil Jones and their daughterSANTA CLARA, Calif. (AP) — San Francisco quarterback Brock Purdy will miss Sunday's game against the Green Bay Packers with a sore throwing shoulder, dealing another blow to the 49ers' playoff hopes. Purdy injured his right shoulder in last Sunday's loss to the Seattle Seahawks . He underwent an MRI on Monday that showed no structural damage and the team initially thought he could play this week. But when Purdy's shoulder didn't feel right when he made a few warmup throws at practice Thursday, those plans changed. “We thought he just needed some rest and we really weren’t concerned about him not being good this week,” coach Kyle Shanahan said Friday. “But when he started up Thursday, it just surprised him, surprised us how it felt. So we had to shut him down.” Shanahan said the team doesn't believe the injury is a long-term concern but he is uncertain whether Purdy will need to miss any additional time. “The MRI doesn’t look like that, so it should be all right,” Shanahan said. “But the way it responded this week, it’s really up in the air for next week. We’ll have to see on Monday.” The 49ers also will be missing star defensive end Nick Bosa, who is out after leaving last week's game in the second half with injuries to his left hip and oblique. Left tackle Trent Williams is questionable with an ankle injury and will be a game-time decision. San Francisco struggled on defense without Bosa last week and now will go the entire game this week without two of the team's most important players. The Niners (5-5) are currently in a three-way tie for second in the NFC West, a game behind first-place Arizona, and have little margin for error if they want to get back to the playoffs after making it to the Super Bowl last season. “I know it’s disappointing,” Shanahan said. “We knew there was a chance for Nick. I think the guys were a little surprised with Brock yesterday, but we addressed all that today. We’re going to have 48 guys in uniform. I know our guys believe in themselves. I believe in them. We’re missing two good players, definitely. But we got a lot of good players out there. So by no means do we not have a chance to win.” This will be the first time Purdy has missed a start because of an injury since taking over as the 49ers’ quarterback in December 2022. Brandon Allen will start in his place. Purdy has completed 66% of his passes this season for 2,613 yards, 13 TDs, eight interceptions and a 95.9 passer rating that is down significantly from his league-leading mark of 113 in 2023. Allen has been mostly a backup since being drafted by Jacksonville in 2016. Allen last started a game in Week 18 of the 2021 season for Cincinnati and has thrown just three passes the last three seasons — including none since joining San Francisco in 2023. Allen said he preparation hasn't changed this week with the exception of getting to work with the first-team receivers instead of running the scout team. “It’s an opportunity.” he said. “The circumstances are what they are. But I think our team all year long we’ve been kind of dealing with injuries here and there. It’s been a big next-man-up mentality. It’s definitely an opportunity for me to go out and play well and put our guys in a good position to win the game. Obviously, we want Brock back and healthy and all that. But for the time being, it is an opportunity for me.” Joshua Dobbs will be the backup Sunday. San Francisco also will be without starting cornerback Charvarius Ward, who returned to the team this week following the death of his 1-year-old daughter on Oct. 28 but needs more time to get back up to speed. Punt returner Jacob Cowing (concussion), linebacker Tatum Bethune (knee) and defensive lineman Kevin Givens (groin) are also out. The Packers will also be without two key defensive players with cornerback Jaire Alexander ruled out after leaving last week's game with a knee injury and linebacker Edgerrin Cooper out with an injured hamstring. AP NFL: https://apnews.com/hub/NFL

Phase 3 Study Results Demonstrated Three Year, Disease-Free Survival of 96% THOUSAND OAKS, Calif. , Dec. 7, 2024 /PRNewswire/ -- Amgen (NASDAQ:AMGN) today announced new data demonstrating that adding BLINCYTO ® (blinatumomab) to chemotherapy significantly improves disease-free survival (DFS) in newly diagnosed pediatric patients with National Cancer Institute (NCI) standard risk (SR) B-cell acute lymphoblastic leukemia (B-ALL) of average or higher risk of relapse. The data are from a Phase 3 study (AALL1731) conducted by the Children's Oncology Group. The results were simultaneously published in the New England Journal of Medicine and will be presented during the plenary session on Sunday, Dec. 8 , at 2 p.m. PT at the 66 th American Society of Hematology (ASH) Annual Meeting & Exposition in San Diego . "Over the last decade, BLINCYTO has reshaped the treatment landscape for B-ALL, offering a critical lifeline for thousands of adult and pediatric patients," said Jay Bradner , M.D., executive vice president of Research and Development and chief scientific officer at Amgen. "These powerful new data leave us little doubt about the profound impact of this medicine for a large number of children affected by this disease. We are grateful to the Children's Oncology Group, along with the patients, families and clinical teams, for their dedication and partnership in advancing this critical study to improve the lives of children with cancer." Based on the results of the first pre-specified interim analysis for efficacy, the study met its primary endpoint of DFS and study randomization was terminated early based on the recommendation from the data and safety monitoring committee due to the benefit observed in the BLINCYTO arm compared to the chemotherapy-only arm. Overall, the 3-year DFS was 96.0% for patients treated with chemotherapy plus BLINCYTO compared to 87.9% for those treated with only chemotherapy. The hazard ratio (HR) was 0.39 [95% confidence interval (CI) 0.24-0.64], indicating a 61% reduction in the risk of disease relapse, secondary malignant neoplasm or remission death with BLINCYTO. At 3 years, more patients remained alive and cancer free when treated with BLINCYTO plus chemotherapy compared to chemotherapy alone. "The AALL1731 study results are truly practice-changing, further solidifying blinatumomab's role as the standard of care for a large number of children with B-ALL," said Sumit Gupta , M.D., Ph.D., FRCPC, co-chair of the Children's Oncology Group AALL1731 study and oncologist and clinician investigator, Division of Haematology/Oncology at The Hospital for Sick Children (SickKids) and associate professor of pediatrics at the University of Toronto . "These breakthrough data showing a significant improvement in disease-free survival are poised to bring substantial clinical value to children with newly diagnosed B-ALL." The addition of BLINCYTO to chemotherapy in standard risk patients resulted in outcomes similar to those previously achieved in only the most favorable pediatric risk subsets. Among SR-Average patients, 3-year DFS was 97.5% for patients treated with BLINCYTO compared to 90.2% for those treated with only chemotherapy (HR 0.33, CI 0.15-0.69). For SR-High patients, 3-year DFS was 94.1% for those treated with BLINCYTO compared to 84.8% for those treated with only chemotherapy (HR 0.45, 95% CI 0.24-0.85). "Relapsed ALL remains a major cause of pediatric cancer mortality, with nearly half of the relapses occurring in children with standard-risk B-ALL," said Rachel E. Rau , M.D., co-chair of the Children's Oncology Group AALL1731 study, pediatric hematologist-oncologist at Seattle Children's Hospital and associate professor of pediatrics at the University of Washington . "These findings underscore the progress made with blinatumomab in preventing relapse and support its role as a critical addition to current therapeutic strategies." Safety results are consistent with the known safety profile of BLINCYTO. BLINCYTO has demonstrated a positive balance of benefits and risks, with only 0.3% of first courses associated with Grade 3+ cytokine release syndrome (CRS) and 0.7% with seizures. A higher risk of infections was observed in the BLINCYTO arm. These results provide the first evidence supporting BLINCYTO for use in the consolidation phase in newly diagnosed pediatric Philadelphia chromosome-negative (Ph-) B-ALL patients. This groundbreaking first-in-class Bispecific T-cell Engager (BiTE ® ) therapy is now backed by additional evidence reinforcing its role in redefining a standard of care for both adult and pediatric patients, starting from one month old, regardless of measurable residual disease (MRD) status. The findings further establish BLINCYTO as a versatile first-line consolidation therapy across all ages and treatment backbones. The NCI's Cancer Therapy Evaluation Program (CTEP), which sponsored the study will share data with the U.S. Food and Drug Administration as part of their ongoing communications relating to the trial. About The Children's Oncology Group The Children's Oncology Group (childrensoncologygroup.org), a member of the NCI National Clinical Trials Network (NCTN), is the world's largest organization devoted exclusively to childhood and adolescent cancer research. The Children's Oncology Group unites over 10,000 experts in childhood cancer at more than 200 leading children's hospitals, universities and cancer centers across North America , Australia , New Zealand and Saudi Arabia in the fight against childhood cancer. Today, more than 80% of the 15,000 children and adolescents diagnosed with cancer each year in the United States are cared for at Children's Oncology Group member institutions. Research performed by Children's Oncology Group institutions over the past 50 years has transformed childhood cancer from a virtually incurable disease to one with a combined 5-year survival rate of 86%. The Children's Oncology Group's mission is to improve the cure rate and outcomes for all children with cancer. About AALL1731 (NCT03914625) The AALL1731 study was a Phase 3 randomized trial to determine if two non-sequential cycles of BLINCYTO added to chemotherapy improved disease-free survival (DFS) in children with newly diagnosed pediatric National Cancer Institute (NCI) standard risk (SR) B-cell acute lymphoblastic leukemia (B-ALL). The study enrolled 4,264 newly diagnosed NCI SR B-ALL patients, of whom 2,334 were risk stratified at the end of induction therapy as either SR-Average or SR-High. At the first planned interim efficacy analysis (data cutoff June 30, 2024 ), 1,440 of the eligible and evaluable patients had been randomized. The AALL1731 study was designed and conducted independently from industry. The Cancer Therapy Evaluation Program (CTEP) of the NCI sponsored the trial and provided funding to the Children's Oncology Group to conduct the study. NCI is part of the National Institutes of Health (NIH). In addition, Amgen provided BLINCYTO and support through an NCI Cooperative Research and Development Agreement. About Acute Lymphoblastic Leukemia (ALL) ALL, also known as acute lymphoblastic leukemia, is a fast-growing type of blood cancer that develops in the bone marrow and can sometimes spread to other parts of the body, including the lymph nodes, liver, spleen and central nervous system. ALL is a rare disease, with an estimated 6,550 new cases, affecting both children and adults, diagnosed in the U.S. in 2024. 1 B-ALL begins in immature cells that would normally develop into B-cell lymphocytes, which are white blood cells that grow in bone marrow. 2,3 B-ALL is the most common type of ALL, constituting approximately 75% of cases in adults and approximately 88% in children, the most common cancer in children. 4,5 About BLINCYTO ® (blinatumomab) BLINCYTO is the first globally approved Bispecific T-cell Engager (BiTE ® ) immuno-oncology therapy that targets CD19 surface antigens on B cells. BiTE ® molecules fight cancer by helping the body's immune system detect and target malignant cells by engaging T cells (a type of white blood cell capable of killing other cells perceived as threats) to cancer cells. By bringing T cells near cancer cells, the T cells can inject toxins and trigger cancer cell death (apoptosis). BiTE ® immuno-oncology therapies are currently being investigated for their potential to treat a wide variety of cancers. BLINCYTO was granted Breakthrough Therapy and Priority Review designations by the U.S. FDA and is approved in the U.S. for the treatment of: In the European Union (EU), BLINCYTO is indicated as monotherapy for the treatment of: BLINCYTO ® IMPORTANT SAFETY INFORMATION WARNING: CYTOKINE RELEASE SYNDROME and NEUROLOGICAL TOXICITIES including IMMUNE EFFECTOR CELL-ASSOCIATED NEUROTOXICITY SYNDROME Contraindications BLINCYTO ® is contraindicated in patients with a known hypersensitivity to blinatumomab or to any component of the product formulation. Warnings and Precautions Adverse Reactions Dosage and Administration Guidelines INDICATIONS BLINCYTO ® (blinatumomab) is indicated for the treatment of CD19-positive B-cell precursor acute lymphoblastic leukemia (ALL) in adult and pediatric patients one month and older with: Please see BLINCYTO ® full Prescribing Information , including BOXED WARNINGS. About Bispecific T-Cell Engager (BiTE ® ) Technology BiTE technology is a targeted immuno-oncology platform that is designed to engage a patient's own T cells to any tumor-specific antigen, activating the cytotoxic potential of T cells to eliminate detectable cancer. The BiTE immuno-oncology platform has the potential to treat different cancer types through tumor-specific antigens. The BiTE platform has a goal of leading to off-the-shelf solutions, which have the potential to make innovative T-cell treatment available to all providers when their patients need it. For more than a decade, Amgen has been advancing this innovative technology, which has demonstrated strong efficacy in hematological malignancies and now a solid tumor with the approval of IMDELLTRA. Amgen remains committed to progressing multiple BiTE molecules across a broad range of hematologic and solid tumor malignancies, paving the way for additional applications in more tumor types. Amgen is further investigating BiTE technology with the goal of enhancing patient experience and therapeutic potential. To learn more about BiTE technology, visit BiTE ® Technology 101 . About Amgen Amgen discovers, develops, manufactures and delivers innovative medicines to help millions of patients in their fight against some of the world's toughest diseases. More than 40 years ago, Amgen helped to establish the biotechnology industry and remains on the cutting-edge of innovation, using technology and human genetic data to push beyond what's known today. Amgen is advancing a broad and deep pipeline that builds on its existing portfolio of medicines to treat cancer, heart disease, osteoporosis, inflammatory diseases and rare diseases. In 2024, Amgen was named one of the "World's Most Innovative Companies" by Fast Company and one of "America's Best Large Employers" by Forbes, among other external recognitions . Amgen is one of the 30 companies that comprise the Dow Jones Industrial Average ® , and it is also part of the Nasdaq-100 Index ® , which includes the largest and most innovative non-financial companies listed on the Nasdaq Stock Market based on market capitalization. For more information, visit Amgen.com and follow Amgen on X , LinkedIn , Instagram , TikTok , YouTube and Threads . Amgen Forward-Looking Statements This news release contains forward-looking statements that are based on the current expectations and beliefs of Amgen. All statements, other than statements of historical fact, are statements that could be deemed forward-looking statements, including any statements on the outcome, benefits and synergies of collaborations, or potential collaborations, with any other company (including BeiGene, Ltd. or Kyowa Kirin Co., Ltd.), the performance of Otezla ® (apremilast) (including anticipated Otezla sales growth and the timing of non-GAAP EPS accretion), Amgen's acquisitions of Teneobio, Inc., ChemoCentryx, Inc., or Horizon Therapeutics plc (including the prospective performance and outlook of Horizon's business, performance and opportunities, any potential strategic benefits, synergies or opportunities expected as a result of such acquisition, and any projected impacts from the Horizon acquisition on Amgen's acquisition-related expenses going forward), as well as estimates of revenues, operating margins, capital expenditures, cash, other financial metrics, expected legal, arbitration, political, regulatory or clinical results or practices, customer and prescriber patterns or practices, reimbursement activities and outcomes, effects of pandemics or other widespread health problems on Amgen's business, outcomes, progress, and other such estimates and results. Forward-looking statements involve significant risks and uncertainties, including those discussed below and more fully described in the Securities and Exchange Commission reports filed by Amgen, including its most recent annual report on Form 10-K and any subsequent periodic reports on Form 10-Q and current reports on Form 8-K. Unless otherwise noted, Amgen is providing this information as of the date of this news release and does not undertake any obligation to update any forward-looking statements contained in this document as a result of new information, future events or otherwise. No forward-looking statement can be guaranteed and actual results may differ materially from those Amgen projects. Discovery or identification of new product candidates or development of new indications for existing products cannot be guaranteed and movement from concept to product is uncertain; consequently, there can be no guarantee that any particular product candidate or development of a new indication for an existing product will be successful and become a commercial product. Further, preclinical results do not guarantee safe and effective performance of product candidates in humans. The complexity of the human body cannot be perfectly, or sometimes, even adequately modeled by computer or cell culture systems or animal models. The length of time that it takes for Amgen to complete clinical trials and obtain regulatory approval for product marketing has in the past varied and Amgen expects similar variability in the future. Even when clinical trials are successful, regulatory authorities may question the sufficiency for approval of the trial endpoints Amgen has selected. Amgen develops product candidates internally and through licensing collaborations, partnerships and joint ventures. Product candidates that are derived from relationships may be subject to disputes between the parties or may prove to be not as effective or as safe as Amgen may have believed at the time of entering into such relationship. Also, Amgen or others could identify safety, side effects or manufacturing problems with its products, including its devices, after they are on the market. Amgen's results may be affected by its ability to successfully market both new and existing products domestically and internationally, clinical and regulatory developments involving current and future products, sales growth of recently launched products, competition from other products including biosimilars, difficulties or delays in manufacturing its products and global economic conditions. In addition, sales of Amgen's products are affected by pricing pressure, political and public scrutiny and reimbursement policies imposed by third-party payers, including governments, private insurance plans and managed care providers and may be affected by regulatory, clinical and guideline developments and domestic and international trends toward managed care and healthcare cost containment. Furthermore, Amgen's research, testing, pricing, marketing and other operations are subject to extensive regulation by domestic and foreign government regulatory authorities. Amgen's business may be impacted by government investigations, litigation and product liability claims. In addition, Amgen's business may be impacted by the adoption of new tax legislation or exposure to additional tax liabilities. If Amgen fails to meet the compliance obligations in the corporate integrity agreement between Amgen and the U.S. government, Amgen could become subject to significant sanctions. Further, while Amgen routinely obtains patents for its products and technology, the protection offered by its patents and patent applications may be challenged, invalidated or circumvented by its competitors, or Amgen may fail to prevail in present and future intellectual property litigation. Amgen performs a substantial amount of its commercial manufacturing activities at a few key facilities, including in Puerto Rico, and also depends on third parties for a portion of its manufacturing activities, and limits on supply may constrain sales of certain of its current products and product candidate development. An outbreak of disease or similar public health threat, such as COVID-19, and the public and governmental effort to mitigate against the spread of such disease, could have a significant adverse effect on the supply of materials for Amgen's manufacturing activities, the distribution of Amgen's products, the commercialization of Amgen's product candidates, and Amgen's clinical trial operations, and any such events may have a material adverse effect on Amgen's product development, product sales, business and results of operations. Amgen relies on collaborations with third parties for the development of some of its product candidates and for the commercialization and sales of some of its commercial products. In addition, Amgen competes with other companies with respect to many of its marketed products as well as for the discovery and development of new products. Further, some raw materials, medical devices and component parts for Amgen's products are supplied by sole third-party suppliers. Certain of Amgen's distributors, customers and payers have substantial purchasing leverage in their dealings with Amgen. The discovery of significant problems with a product similar to one of Amgen's products that implicate an entire class of products could have a material adverse effect on sales of the affected products and on its business and results of operations. Amgen's efforts to collaborate with or acquire other companies, products or technology, and to integrate the operations of companies or to support the products or technology Amgen has acquired, may not be successful. There can be no guarantee that Amgen will be able to realize any of the strategic benefits, synergies or opportunities arising from the Horizon acquisition, and such benefits, synergies or opportunities may take longer to realize than expected. Amgen may not be able to successfully integrate Horizon, and such integration may take longer, be more difficult or cost more than expected. A breakdown, cyberattack or information security breach of Amgen's information technology systems could compromise the confidentiality, integrity and availability of Amgen's systems and Amgen's data. Amgen's stock price may be volatile and may be affected by a number of events. Amgen's business and operations may be negatively affected by the failure, or perceived failure, of achieving its environmental, social and governance objectives. The effects of global climate change and related natural disasters could negatively affect Amgen's business and operations. Global economic conditions may magnify certain risks that affect Amgen's business. Amgen's business performance could affect or limit the ability of the Amgen Board of Directors to declare a dividend or its ability to pay a dividend or repurchase its common stock. Amgen may not be able to access the capital and credit markets on terms that are favorable to it, or at all. Any scientific information discussed in this news release relating to new indications for Amgen's products is preliminary and investigative and is not part of the labeling approved by the U.S. Food and Drug Administration for the products. The products are not approved for the investigational use(s) discussed in this news release, and no conclusions can or should be drawn regarding the safety or effectiveness of the products for these uses. CONTACT: Amgen, Thousand Oaks Elissa Snook , 609-251-1407 (media) Justin Claeys , 805-313-9775 (investors) References View original content to download multimedia: https://www.prnewswire.com/news-releases/blincyto-blinatumomab-added-to-chemotherapy-significantly-improves-survival-in-newly-diagnosed-pediatric-patients-with-b-cell-precursor-acute-lymphoblastic-leukemia-b-all-302325381.html SOURCE Amgen

The Indian Army has organised ‘Know Your Army Mela 2025’, a three-day event aimed at showcasing the strength, technological advancements and indigenous capabilities of the Armed Forces between January 3 and 5, 2025 at Royal Western India Turf Club (RWITC). According to the Southern Command, the event reflects the Indian army’s commitment to fostering stronger connections with citizens while celebrating its transformative journey. The exhibition will feature a range of military equipment and technologies, offering visitors a unique glimpse into the operational capabilities of the Indian army. The exhibition and display section will showcase Infantry and Special Forces equipment, such as K-9 Vajra, 155 MM BOFORS, PINAKA and SMERCH, T-90 and BMP-II tanks by mechanised forces, Air Defence systems, including L-7-, ZU-23, Akash and the upgraded Schilka and Swarm drones and other newly inducted vehicles, demonstrating advancements in protection and mobility. A dedicated section showcasing 25 vendors contributing to Atmnirbhar Bharat, highlighting indigenous equipment production will be set up for the visitors along with an immersive photo exhibition displaying the capabilities of armed forces. There will be a dynamic display of one hour consisting of martial music, martial arts, an army dog show, a horse show, and traditional performances on all days. Comprehensive arrangements have been made to ensure convenient access and smooth parking for visitors at the racecourse venue near the parade ground entrance for school and college buses.Rocky Mountain Advisers LLC Has $532,000 Stock Position in Alphabet Inc. (NASDAQ:GOOGL)

No. 13 Texas A&M routs Abilene Christian 92-54, Taylor moves into 2nd in Aggies' all-time scoring

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