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Video games allow man born with Maffuci syndrome to connect to wider world - ABC News

SANTA CLARA, Calif. (AP) — Getting blown out at Green Bay following another squandered late lead the previous week against Seattle has quickly turned the San Francisco 49ers from a Super Bowl contender into a team just fighting to get back to the playoffs. Read this article for free: Already have an account? To continue reading, please subscribe: * SANTA CLARA, Calif. (AP) — Getting blown out at Green Bay following another squandered late lead the previous week against Seattle has quickly turned the San Francisco 49ers from a Super Bowl contender into a team just fighting to get back to the playoffs. Read unlimited articles for free today: Already have an account? SANTA CLARA, Calif. (AP) — Getting blown out at Green Bay following another squandered late lead the previous week against Seattle has quickly turned the San Francisco 49ers from a Super Bowl contender into a team just fighting to get back to the playoffs. If San Francisco doesn’t get healthy and eliminate the errors that led to Sunday’s 38-10 loss to the Packers, the focus will turn from playoff permutations to what offseason changes are necessary. “I think everyone understands completely outside and inside what the situation is,” coach Kyle Shanahan said Monday. “That’s why the Seattle game was so tough of a loss and that’s why last night was even worse. We know what we got ahead of us. We know exactly what the playoff situation is. That is what it is. But really, all that matters is this week when you do need to go on a run and put a lot of wins to even think of that.” The task doesn’t get any easier as the Niners (5-6) get set to play at Buffalo on Sunday night. The 49ers are hoping to get injured stars Brock Purdy, Nick Bosa and Trent Williams back for that game, but their presence alone won’t fix everything that went wrong on Sunday. The defense got repeatedly gashed early and put San Francisco in a 17-0 hole before the offense even generated a first down. The running game never got going as Christian McCaffrey has looked nothing like the 2023 Offensive Player of the Year in his three games back from Achilles tendinitis. And whenever the Niners appeared to do something right, a penalty came back to haunt them. It added up to the most lopsided loss for San Francisco since the 2018 season, before Shanahan had turned the Niners into perennial contenders. “It’s probably one of the worst ones I’ve been a part of,” linebacker Fred Warner said. “It is embarrassing. You’ve got to take it on the chin, take it like a man and move on.” Despite the doom and gloom, the 49ers are only one game behind Seattle and Arizona in the NFC West standings with six games to go. But San Francisco already has three division losses and a difficult schedule featuring games against the Bills this week and Detroit in Week 17. “My optimism is not broken by any means,” tight end George Kittle said. “We still have a lot of very talented players. We will get some guys back and I still have full trust in the coaching staff to put our guys in position to make plays. I have no worry about that. But definitely an uphill grind. We’ll see what we’re made of, which I’m looking forward to.” What’s working Red-zone passes to Kittle. Backup QB Brandon Allen connected on a 3-yard TD pass to Kittle late in the second quarter for San Francisco’s only TD. Kittle leads the NFL with eight touchdown catches in the red zone, which is tied with Vernon Davis (2013) for the most in a season for a Niners player since 2000. Kittle was the only consistent part of the San Francisco offense with six catches for 82 yards. What needs help Avoiding penalties. San Francisco had nine penalties for 77 yards and they were costly and sloppy. The Niners had 12 men on the field on defense on back-to-back plays, three false starts, a pass interference in the end zone and three penalties on special teams, including a holding on Eric Saubert that negated an 87-yard kickoff return by Deebo Samuel to open the second half. Rookie Dominick Puni had three penalties after being penalized just once in the first 10 games. Stock up DE Leonard Floyd. There were few positive performances on defense, but Floyd had both of the team’s sacks. Stock down Run defense. San Francisco allowed 169 yards rushing, including 87 in the first quarter for the team’s second-worst performance in the opening quarter since 1991. The Niners missed 19 tackles, according to Pro Football Focus, as Josh Jacobs gained 83 of his 106 yards rushing after contact. Injuries Purdy took part in a light throwing session without pain on Monday and Shanahan is hopeful he can return to practice Wednesday after missing the Green Bay game with a shoulder injury. ... Bosa (hip, oblique) and Williams (ankle) also could return this week after sitting out Sunday. ... LG Aaron Banks, DT Jordan Elliott and WR Jacob Cowing all in the concussion protocol. ... RG Dominick Puni (shoulder) and CB Deommodore Lenoir (knee) underwent MRIs on Monday and the team is waiting for results. ... CB Renardo Green (neck) and LB Demetrius Flannigan-Fowles (knee) are day to day. Key number Winnipeg Jets Game Days On Winnipeg Jets game days, hockey writers Mike McIntyre and Ken Wiebe send news, notes and quotes from the morning skate, as well as injury updates and lineup decisions. Arrives a few hours prior to puck drop. 11 — The Niners generated only 11 first downs, tied for the fewest in any game in eight seasons under Shanahan. They also had 11 in the 2022 NFC title game loss at Philadelphia when Purdy hurt his elbow and in Week 2 against Seattle in Shanahan’s first season in 2017. What’s next The 49ers visit Buffalo on Sunday night. ___ AP NFL: https://apnews.com/hub/NFL Advertisement Advertisement

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Ex-OpenAI engineer who raised legal concerns about the technology he helped build has diedMINOT — Artificial intelligence. Whether you love it, hate it or are indifferent, it's here, and there are important questions about how it will be used and what sort of opportunities it presents for our region, which policymakers need to discuss. Rep. Josh Christy is a first-term Republican lawmaker from Fargo who is heading into his second legislative session. He's also what you could call an AI professional. He's an entrepreneur, software development executive and consultant who works with AI and AI policies on a regular basis. ADVERTISEMENT "Two years ago, generative AI was not something anyone was talking about," he said, referring to his first session in Bismarck. But now it's here. Teachers are using it. Students are using it. The business community is using it. On this episode of Plain Talk, Christy argued that it's time for North Dakota's laws to catch up. "With any type of technology, there's the good, the bad, the ugly," Christy said, and he's got legislative proposals for each of those. One bill he has developed in conjunction with Attorney General Drew Wrigley's office would address abusive uses of AI. Say, to develop images or videos of public figures for nefarious purposes or of children for sexual gratification. "People are using this to generate images of children in compromising positions," Christy said, and current law doesn't necessarily address that. But other initiatives Christy proposes would seek to welcome the AI industry into North Dakota as a partner. Christy proposes leveraging North Dakota's oil, gas and coal resources to help power data centers. He wants to develop "computing credits" that could help facilitate the data industry's move into the state. He'll be pushing these bills during the upcoming legislative session, which begins in January. Also on this episode, Chad Oban and I discuss the ongoing controversies around Burleigh County auditor Mark Spolonskowski, the efforts to recall Dickinson city commissioner Jason Fridrich, the arrest of Luigi Mangione, who is accused of gunning down an insurance industry executive in Manhattan, and what all those stories mean for our society's notions about right and wrong. If you want to participate in Plain Talk, just give us a call or text at 701-587-3141. It’s super easy — leave your message, tell us your name and where you’re from, and we might feature it on an upcoming episode. To subscribe to Plain Talk, search for the show wherever you get your podcasts or use one of the links below. Apple Podcasts | Spotify | YouTube | Pocket Casts | Episode Archive ADVERTISEMENT

It appears that the Detroit Tigers have finally emerged from the ashes of their long and grueling rebuild — and not a moment too soon. Detroit was baseball’s biggest surprise this past season, as the team went from being a seller at July’s trade deadline to knocking off perennial World Series contender Houston in the postseason. Despite a flawed roster with various holes, thanks to the combination of gritty players, some good fortune and a manager in AJ Hinch who kept everything together, the Tigers found a way to become 2024’s Cinderella team. And now, this offseason provides Detroit a unique opportunity to build off their success and get back to being a powerhouse in the AL Central. Detroit has quietly developed a handful of talented players at the big-league level, including Riley Greene and Kerry Carpenter. Greene is a budding star who earned his first All-Star appearance this past season and is a staple in the middle of Detroit’s lineup. Carpenter has become one of the better left-handed bats in the American League, and while he spent time in '24 on the injured list, he posted an impressive .932 OPS with 18 homers and looked very comfortable hitting in the postseason. The crown jewel of the Tigers’ turnaround is none other than 2024 AL Cy Young Award winner Tarik Skubal. He has been one of the best pitchers in baseball since his return from left flexor tendon surgery in late 2023. His performance skyrocketed last season as he turned himself into arguably the best starter in MLB. While many wondered during his phenomenal season if the Tigers would trade Skubal, the decision to not move the young star was arguably the biggest turning point of Detroit’s season. And as Skubal continued to dominate in the season’s second half, Detroit continued to win. Coming off their surprise success in '24, the Tigers still have a young and inexperienced roster. The team’s moves this winter should be focused on raising their ceiling while supporting the core pieces on the current roster so they can take the next jump. From an offensive standpoint, the Tigers were one of the more left-handed lineups in baseball last season. They would benefit tremendously from adding a right-handed bat or two. One of the . He would bring a boatload of veteran and postseason experience to a young team on the rise and fill a big hole at third. Not to mention, this pairing would give him the opportunity to play for his former manager in Hinch. The other question for Detroit to answer on offense is what will the Tigers do with Javier Báez and Spencer Torkelson? Báez has been a disaster in Detroit and missed most of the second half of 2024 due to a hip injury. Detroit acquired rookie shortstop Trey Sweeney in the July trade that sent Jack Flaherty to the Dodgers, and now Sweeney needs a place to play. Báez will have to at least show that he can hit against left-handers if he hopes to see time consistently next season. As for Torkelson, he has not lived up to the hype that accompanied him when he was the No. 1 pick in the 2020 MLB Draft. His inability to hit consistently at the big-league level has been a speed bump in the Tigers’ rebuild. While Torkelson will likely get one more opportunity to show he belongs in the big leagues, there are possible upgrades on the market. Free agent Christian Walker . If the Tigers aren’t looking to spend at that level, someone such as Carlos Santana could provide similar traits for much less. Detroit could also use a few veteran arms to add to its rotation behind Skubal. Detroit's rotation, or lack thereof, was one of the main reasons its season came to an end in the ALDS. The Tigers didn’t have enough starting pitching for a full postseason series and were forced to go with openers and bullpen games. The Tigers would particularly benefit from some experience to go with their relatively young rotation. Starters such as Walker Buehler and Sean Manaea could be the type of experienced arms that would fit the Tigers’ needs. The AL Central surprised the entire sport this year, with three teams reaching the postseason in the Tigers, Royals and Guardians. All three advanced at least one round. Going forward, the advantage the Tigers have over the other teams in the division is their ability to spend. Their payroll for 2024 was $98.5 million, and they have a projected payroll of just $79 million for 2025, which would rank 27th in the league, according to Spotrac. Historically, the Tigers have never been afraid to flex financial might in free agency or make a big splash in the trade market. And outside of Báez, who is owed $73 million over the next three years, the Tigers don't have huge financial commitments, and most of their roster is still pre-arbitration. With the retired Miguel Cabrera’s massive contract finally off the books, Detroit has the kind of financial flexibility the organization hasn’t enjoyed in more than a decade. In his two years with the Tigers, president of baseball operations Scott Harris has been methodical in his approach to building the roster. But after Detroit’s standout 2024 with a team that had some holes, a few key additions this winter could give the Tigers a strong chance to make back-to-back postseasons for the first time since 2013-14.

Big Ten slate features Indiana-Ohio State showdown and Penn State-Minnesota matchup Things to watch this week in the Big Ten Conference: No. 5 Indiana (10-0, 7-0 Big Ten, No. 5 CFP ) at No. 2 Ohio State (9-1, 6-1, No. 2 CFP), Saturday, noon ET (Fox) This marks the 98th matchup between these two teams, but it's only the fourth time both teams have been ranked. Although Indiana is unbeaten, its soft schedule means the Hoosiers aren't assured of making the 12-team field if they lose this game. The only team with a winning record that Indiana has beaten is Washington (6-5). Ohio State needs a win to have a realistic shot at a rematch with top-ranked Oregon in the Big Ten championship game. Ohio State has beaten Indiana 28 straight times since the Hoosiers posted back-to-back victories in 1987-88. No. 4 Penn State (9-1, 6-1, No. 4 CFP) at Minnesota (6-4, 4-3), Saturday, 3:30 p.m. (CBS) This is likely Penn State's biggest obstacle on its way to a potential playoff berth. The Nittany Lions' lone remaining regular-season game is a Nov. 30 home matchup with Maryland (4-6, 1-6). Minnesota has had an extra week to prepare this game since its 26-19 loss at Rutgers on Nov. 9, which snapped a four-game winning streak. Penn State and Minnesota have split their last four meetings, with the home team winning each time. Penn State DE Abdul Carter has multiple tackles for loss in each of his last three games. He ranks second among all Bowl Subdivision players in tackles for loss (17 1⁄2). Southern California RB Woody Marks rushed for a career-high 146 yards in a 28-20 win over Nebraska. Marks has six 100-yard rushing performances this season. Rutgers RB Kyle Monangai is the first Scarlet Knight to rush for 1,000 yards in back-to-back seasons since Ray Rice did it three straight years from 2005-07. Monangai has run for 1,028 yards this season and rushed for 1,262 yards last year. Oregon OLB Matayo Uiagalelei recorded a sack and had a game-clinching interception as the top-ranked Ducks won 16-13 at Wisconsin last week. He has 8 1⁄2 sacks this season to rank second in the Big Ten. Four of the top seven Bowl Subdivision quarterbacks in passer rating are from the Big Ten. Indiana's Kurtis Rourke is second, Ohio State's Will Howard is third, Penn State's Drew Allar is fifth and Oregon's Dillon Gabriel is seventh. ... Illinois QB Luke Altmyer has thrown 18 touchdown passes with only three interceptions. The only Power Four quarterback with a better touchdown/interception ratio while throwing at least 10 touchdown passes is Clemson's Cade Klubnik, who has 26 touchdowns and four interceptions. ... Rutgers' three Big Ten wins matches its largest total since joining the league in 2014. Rutgers also had three conference wins in 2014, 2017, 2020 and 2023. A victory Saturday over No. 24 Illinois would give Rutgers three straight Big Ten wins for the first time. ... Washington's 31-19 win over UCLA was its 20th straight home victory, representing its second-longest such streak in school history. The Huskies won 45 straight home games from 1908-17. ... Wisconsin heads to Nebraska this week having won its last 10 matchups with the Cornhuskers. Penn State justifiably is favored on the road against Minnesota, but Bet MGM's 12 1⁄2-point spread seems way too big. Expect this game to have a single-digit margin.Groundbreaking Directive Ensures ALS Patients on Medicare Advantage Gain Access to Qalsody

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The year 2024 has witnessed a quantum leap in the application of artificial intelligence (AI), permeating every facet of life and presenting a blend of promises and challenges. This comprehensive exploration delves into the innovative breakthroughs and ethical dilemmas introduced by AI, revealing its profound impact across various sectors. Transformative Breakthroughs in AI Artificial intelligence has achieved groundbreaking advancements in problem-solving capabilities, outperforming PhD-level scientists in fields such as chemistry, physics, and biology. It has also earned recognition in prestigious platforms like the Nobel Prizes, affirming its influence in both theoretical and practical domains. Moreover, AI has become a staple in everyday technologies, enhancing functionalities in devices from global tech giants like Apple, Samsung, and Google, making sophisticated AI tools accessible to a broader audienc. AI in Daily Life and Work AI’s integration into daily life is more profound than ever. In the retail sector, AI technologies have revolutionized the shopping experience by personalizing product recommendations both online and in-store. In the workplace, AI-driven decision-making tools have redefined business operations and healthcare, enhancing efficiency and accuracy in decision-making processes, particularly in diagnostics and patient care. Environmental and Social Implications AI’s role in environmental sustainability has been significant, aiding in monitoring and managing natural resources and contributing to disaster preparedness. Socially, AI has supported movements for equality and inclusion, though it has also been a tool for exacerbating geopolitical tensions and economic disparities, reflecting the dual-edged nature of technological advancements. Ethical Considerations and Future Prospects The expansion of AI has not been without ethical concerns. Issues surrounding data privacy, transparency, and the potential for bias pose significant challenges that necessitate stringent regulatory frameworks. Looking ahead to 2025, AI is expected to further personalize user experiences across various sectors, including education and healthcare, and play a critical role in combating climate change through innovative solutions . AI in 2024 has proven to be both a remarkable asset and a formidable challenge, highlighting the need for careful consideration of its developmental trajectory. As we harness AI’s capabilities, it is imperative to balance innovation with ethical responsibility to steer future advancements toward the betterment of society at large.Sony to Take On Nintendo with New PlayStation Handheld - IGN Daily Fix

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The e-commerce and technology behemoth will remain a minority investor in Anthropic, having pumped an initial $4 billion into the artificial intelligence developer late last year and becoming its primary cloud computing provider. "The response from AWS customers who are developing generative AI applications powered by Anthropic in Amazon Bedrock has been remarkable," said Matt Garman, chief of AWS cloud computing division. "We'll keep pushing the boundaries of what customers can achieve with generative AI technologies." Amazon is investing the additional $4 billion in Anthropic as part of an expanded alliance that includes working together on "Trainium" hardware to optimize machine learning, according to the companies. "We're looking forward to working with Amazon to train and power our most advanced AI models using AWS Trainium, and helping to unlock the full potential of their technology," said Anthropic chief executive Dario Amodei. The announcement came just days after Britain's competition regulator cleared Google-parent Alphabet's investment in Anthropic, following a probe. The Competition and Markets Authority concluded that the big tech giant had not acquired "material influence" over Anthropic as a result of the deal, which was reported to have cost $2 billion. The British regulator is one of several global regulators concerned with reining in big tech companies and their partnerships with AI firms. In September, the CMA cleared Amazon's initial investment in Anthropic, saying it did not believe that "a relevant merger situation has been created." gc/mlmBiden approves national security memo on China, Iran, North Korea and Russia ahead of Trump's return