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world series of poker game Hibs' ultras group spray painted 'Sack the Board' outside Easter Road in protest after their latest damaging defeat to Dundee . Discontent is rife among punters in Leith after a disastrous start to the season leaves them rooted to the bottom of the Premiership table. They were hammered 4-1 on Saturday with the permanent appointment of David Gray as head coach so far not going to plan. But there's a feeling among Hibs fans that the problems run far deeper with the unpopular appointment of Malky Mackay as director of football still a bone of contention, particularly when it has failed to translate into success on the pitch. There have also been rumbles of a power struggle behind the scenes between the Gordon family and new part owner, Bill Foley, and his Black Knights. It all leaves the club entrenched in turmoil and it seems the outspoken Ultras group Block Seven have had enough. They spraypainted the clear message 'Sack the Board' on a wall just yards Easter Road. And they shared it on social media with the message 'enough is enough.' Tune in to Hotline Live every Sunday to Thursday and have your say on the biggest issues in Scottish football.

Indigenous leaders voice hope and skepticism at COP29

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MOUNTAIN VIEW, Calif., Dec. 03, 2024 (GLOBE NEWSWIRE) -- NeuroPace, Inc. NPCE , a commercial-stage medical device company focused on transforming the lives of people living with epilepsy, today announced completion of enrollment and implant procedures in its feasibility investigational device exemption (IDE) study of the RNS® System for the treatment of Lennox-Gastaut Syndrome (LGS), a devastating form of childhood-onset epilepsy characterized by cognitive dysfunction and frequent generalized onset seizures that often lead to injury. The IDE study uses the RNS System, which has demonstrated safety and effectiveness of brain-responsive stimulation for treating medically intractable focal onset seizures in people 18 and older, to evaluate whether brain-responsive neurostimulation can also be used to treat LGS. NeuroPace received a $9.3 million National Institutes of Health (NIH) grant through the Brain Research through Advancing Innovative Neurotechnologies® (BRAIN) Initiative to evaluate its responsive neuromodulation technology in those who suffer from LGS. The IDE study funded by the grant was conducted at six sites and enrolled a total of 20 patients 12 years of age and older with LGS and drug-resistant generalized onset seizures. The study will evaluate the safety and effectiveness of the RNS System in treating seizures associated with LGS. "We are pleased to announce the advancement of our LGS IDE study and look forward to the data and learnings it provides. The results from this study could support further research of RNS therapy to improve the treatment of people with LGS. We appreciate the dedicated efforts of the investigators, research teams, participants and their families," said Martha Morrell, MD, Chief Medical Officer of NeuroPace. "After completing the one-year open label period, participants will transition to the long-term follow-up period, which will continue over the next 18 months." "LGS is a devastating, childhood-onset seizure disorder that leads to lifelong disability. 85% of those with LGS continue to have seizures into adulthood despite aggressive treatment, 98% suffer from intellectual disability, and they are 12 times more likely to die prematurely than others their age," said Tracy Dixon-Salazar, PhD, Executive Director of the LGS Foundation and mother of an adult living with LGS. "LGS families desperately need innovative treatment options to manage their seizures, and we are excited about this new study." Disclaimer: Research reported in this press release was supported by the National Institutes of Health's Brain Research Through Advancing Innovative Neurotechnologies (BRAIN) Initiative under award number UH3NS109557. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. About the RNS® System The RNS® System, a paradigm-shifting treatment for drug-resistant focal epilepsy, is the only brain-responsive neuromodulation system approved by the FDA. The closed-loop technology delivers personalized, data-driven treatment targeted to the seizure source by continuously monitoring brain activity, recognizing a patient's unique seizure pattern, and responding in real-time with imperceptible stimulation to prevent seizures. By recording ongoing EEG data, the RNS System provides physicians with a unique "window to the brain," enabling them to remotely monitor their patients, gain insights based on brain activity, and use that information to optimize patient care. Long-term clinical studies demonstrate that the RNS System provides significant reduction in seizure frequency and enduring improvements in quality of life and cognition with no stimulation-related side effects. The RNS System is available at most comprehensive epilepsy centers in the United States and is widely covered by insurance. It is currently approved in the United States as an adjunctive therapy for patients 18 years of age and older with drug-resistant focal epilepsy. See full indication for use and important safety information at www.neuropace.com/safety/ . About NeuroPace, Inc. Based in Mountain View, Calif., NeuroPace is a commercial-stage medical device company focused on transforming the lives of people living with epilepsy by reducing or eliminating the occurrence of debilitating seizures. Its novel and differentiated RNS System is the first and only commercially available, brain-responsive platform that delivers personalized, real-time treatment at the seizure source. This platform can drive a better standard of care for patients suffering from drug-resistant epilepsy and has the potential to offer a more personalized solution and improved outcomes to the large population of patients suffering from other brain disorders. Forward Looking Statements This press release may contain forward-looking statements made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. These statements may be identified by words such as "aims," "anticipates," "believes," "could," "estimates," "expects," "forecasts," "goal," "intends," "may," "plans," "possible," "potential," "seeks," "will" and variations of these words or similar expressions that are intended to identify forward-looking statements, although not all forward-looking statements contain these words. Actual results or events could differ materially from the plans, intentions and expectations disclosed in these forward-looking statements as a result of various factors, including: risks related to regulatory compliance and expectations for regulatory approvals to expand the market for NeuroPace's RNS System and other important factors. These and other risks and uncertainties include those described more fully in the section titled "Risk Factors" and "Management's Discussion and Analysis of Financial Condition and Results of Operations" and elsewhere in NeuroPace's public filings with the U.S. Securities and Exchange Commission (SEC), including its Quarterly Report on Form 10-Q for the quarter ended September 30, 2024, filed with the SEC on November 12 , 2024, as well as any other reports that it may file with the SEC in the future. Forward-looking statements contained in this announcement are based on information available to NeuroPace as of the date hereof. NeuroPace undertakes no obligation to update such information except as required under applicable law. These forward-looking statements should not be relied upon as representing NeuroPace's views as of any date subsequent to the date of this press release and should not be relied upon as a prediction of future events. In light of the foregoing, investors are urged not to rely on any forward-looking statement in reaching any conclusion or making any investment decision about any securities of NeuroPace. Investor Contact: Jeremy Feffer Managing Director LifeSci Advisors jfeffer@lifesciadvisors.com © 2024 Benzinga.com. Benzinga does not provide investment advice. All rights reserved.The opposition in Singapore is here to stay and there is "no chance" of an opposition wipe-out happening in the next general election, Prime Minister Lawrence Wong said. He was speaking at the People's Action Party (PAP) party conference on Nov. 24, 2024 where he spoke about the political challenges that Singapore is facing. No chance of opposition wipe-out Opposition MPs have been in Parliament ever since 1981 , when JB Jeyaretnam of the Workers' Party was elected in the Anson by-election. With the Non-constituency Member of Parliament (NCMP) scheme, Singaporeans are also guaranteed of at least 12 opposition MPs in parliament, PM Wong said. However, given the desire for more opposition voices, the "bigger risk we face" is the loss of a government that's "stable", "strong" and "good". The next election will bring high stakes, and there are "no longer any safe seats". This means that there is no guarantee that the PAP will win and form a stable government, he explained. PM Wong added that the opposition themselves admit that they are not yet ready to form the government. In April 2024, WP leader Pritam Singh clarified that his party's medium-term goal is to "play their part" to deny the PAP a majority of more than two-thirds of the seats in Parliament, following an opinion column in the Straits Times. PM Wong cautioned that it does not take a large number of swing votes to significantly change electoral outcomes. "A modest swing in popular votes against the PAP can lead to very different electoral outcomes. We are talking very possibly the loss of another three or four GRCs. That means we lose another four or five ministers, or a quarter of the Cabinet. We will end up with a much weaker government; with far less ability to solve the problems facing our people and our country, at a time when the world is becoming more uncertain and troubled." Challenges in recruiting One of PM Wong's priorities is to assemble the "best team for Singapore". He outlined his challenges in getting potential candidates to join, as many Singaporeans are reluctant to change their lifestyles or subject themselves to public scrutiny. PM Wong had also asked his predecessors, Senior Minister Lee Hsien Loong, and Emeritus Senior Minister Goh Chok Tong, for advice on this front. "It's never easy to get good people to enter politics. I asked my two predecessors, ESM Goh and SM Lee, 'Do you have any advice and tips for me?' They say, 'Just do your best, this has always been challenging.' They too face difficulties attracting good people to join. In fact, I've seen how SM Lee agonised over this when I worked with him at that time, I didn't quite fully understand the significance of this work. Now, having taken over, I realise it's absolutely the most important, the most crucial, the most urgent thing I have to do." While he shared that he has made some progress on that front, he still hopes to persuade a few more to join the team. These new candidates will be presented as the campaign approaches. Top photo from PAP Singapore/Facebook, Mothership.

Silver Voices is calling on all MPs not to duck this rare opportunity to agree legislation to enshrine the right of a terminally ill patient to choose the exact place and time of their death. Who wants to pass away comatose on a hospital bed, undignified with multiple tubes everywhere, and unable to say goodbye to close family and friends? Who wants to spend their last few weeks in pain, gradually losing control of their functions and increasingly unable to communicate? Who wants loving partners to be criminalised because they are trying to carry out their loved one’s last wishes? A ‘good death’ is what we all hope for, and is so important for family memories too. Older people are the most likely to face these dilemmas and yet there has been no organisation bold enough to find out what senior citizens think about this topic. We have tested our membership in a big anonymous poll about whether they support the precise Bill being voted on and a significant majority has voiced its support. But we do recognise that a sizeable minority of our members has worries about the Bill, particularly whether the safeguards will prevent a slippery slope from a choice for assisted dying to an expected duty on older people to do so. Also, there is great concern, even amongst the Bill’s supporters, that the poor state of palliative and social care in the UK will force people to choose the assisted dying option when they shouldn’t have to do so. Questions have also been raised on practicalities such as whether insurance policies could be invalidated. If, as I hope, the Bill passes its Second Reading this week, it will be incumbent on the Government to ensure there is as much time as possible to debate the complications and worries of opponents and to agree sensible amendments to strengthen safeguards. Squeezing scrutiny time on such consequential legislation would indicate that the Government is not serious about supporting the principle of assisted dying. If the Bill does not get through its Second Reading or is scuppered by a lack of parliamentary time, we may have to wait many more years for the issue to be considered again.When the Fortnite Chapter 5 and Remix Finale event takes the stage in-game on November 30, it will feature a pack of four iconic musical artists: Snoop Dogg, Eminem, Ice Spice, and Juice WRLD. Like previous in-game concerts, such as those starring Travis Scott and Ariana Grande, the event is likely to be a kaleidoscopic audiovisual roller coaster. Still, by including the late Juice WRLD, who passed away in 2019, this in-game concert will also be decidedly different from any before seen in Fortnite: It will be the first to use an artist's likeness posthumously, something that Hollywood is also grappling with as of late . GameSpot recently spoke to Nate Nanzer, Epic's head of global partnerships, in a music-focused interview that hit on the developer-publisher's decision to bring Juice WRLD, whose real name is Jarad Anthony Higgins, to Fortnite. Nanzer told me Epic had long hoped to do something like this with the late artist and explained why the company feels now is the right time. "It's something that our players have been asking for for years and years and years, and we've wanted to do it, but we wanted to find the right moment," Nanzer said. "We obviously want to do it in the most respectful way possible. We worked very closely with his mom and his label, and we were able to find the right moment where it felt right, around this event, and he has new music coming out, so all the stars kind of aligned around this moment." Nanzer mentioned that Juice WRLD himself was "a big Fortnite player," and though the Epic executive didn't say this, it stands to reason that Juice WRLD would want to be in the game if he could say so today. Still, even with the involvement of his family and his music label, for some, the inclusion of a deceased artist's likeness in this manner may always cross a line. In the movie world, Robert Downey Jr. recently said he plans to sue anyone who tries to create an AI replica of his likeness , and that even if it were to occur after he has died, his "law firm will still be very active." Events in 2012 surely predate many of Fortnite's biggest fans, but the Juice WRLD concert also recalls the Tupac "hologram" that once performed at Coachella . In the Fortnite world, I haven't personally seen a lot of pushback to Juice WRLD's involvement in next weekend's event. Certainly, there have been some feelings of ethics-based squeamishness, but the prevailing sentiment on places like the game's subreddit and popular Discord servers is one of excitement, perhaps owing to the often younger player pool in Fortnite. Whereas older players and onlookers may see this as a line being crossed, younger players who have already spent years growing up within Fortnite may more quickly accept this as a marvel of modern technology, and they may be excited to finally have the Fortnite Juice WRLD event Nanzer says has been one of the community's most requested. "Our community loves his music. We have data [that shows he is] still extremely popular. And I would say, I can't quantify this, but when I look at Reddit threads, or Discord chats, or Twitter threads, Juice WRLD comes up over and over and over again. I mean, people have made Juice WRLD concerts in Fortnite Creative and [Unreal Engine for Fortnite]." Nanzer added that he feels fans of the late artist will come out of the event with positive feelings. "We're hopeful. We know our players have been asking for it, so there's a lot of pressure to really deliver it the right way. I think people are really gonna love what we have coming, like, I think it's done in an awesome way. I think if you're a Juice WRLD fan, you're gonna feel good about it," he said. As mentioned, Juice WRLD's mother, Carmela Wallace, was involved in this collaboration. Earlier this month, she shared remarks on the upcoming event, which you can read in full below. The debate over when it is or isn't acceptable to use a deceased person's likeness won't end when Fortnite Chapter 5 does next weekend, but Nanzer told me the company wants "music to permeate everything in Fortnite," which likely means this isn't the last time Fortnite will court controversy, even unintentionally, as it strives to fulfill its vision of a multimedia metaverse. In fact, there are already rumors that a future Fortnite collaboration will revolve around XXXTentacion, a musical artist who was murdered in 2018 at the age of 20. Fortnite is a tastemaker on a global scale. Much of the games industry over the past half-decade has been mired in chasing lucrative trends that Fortnite started or had massive success with. Once meant to be nothing more than a survival game, Fortnite is today an increasingly hard-to-define platform that doesn't merely feature pop culture; it shapes it. As Epic continues down this path of making the ultimate everything experience, it's inevitably molding what the future looks like, whether we're ready to live there or not. Editor's note: Remarks from Mrs. Wallace were added to the body of this story shortly after publishing.

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Seahawks Rookie LB Notches First Career Sack Early Against Kyler MurrayThe vessels will help limit oil, diesel and other pollutant spills at inland waterways and each vessel can tow and deploy absorbent and containment booms to limit hazardous spills. They also carry specialised equipment designed to contain and recover contaminants, reducing environmental harm during an incident. The vessels are fitted with advanced emissions technology using the most efficient controls available to help minimise their environmental impact. The new locally made vessels replace a 15-year-old fleet and offer larger and more stable platforms for crews to operate from. They are strategically located around NSW to be deployed at any time with response times of under two hours. Three vessels already have been delivered to locations in Bathurst, Newcastle and Shellharbour, while additional units will be delivered to Batemans Bay, Berkeley Vale, Broken Hill, Coffs Harbour, Dubbo, Eden, Goonellabah, Leeton, Lithgow, Port Macquarie, Tamworth, Tweed Heads and Wagga Wagga over coming months. Operators of the HAZMAT vessels undergo rigorous training, ensuring crews are prepared for complex incidents. Training is planned for teams in Berkeley Vale by the end of the year with the remaining boats to be rolled out by June 2025. The $1.58M fleet is part of the NSW Government’s $18.6M investment in Fire and Rescue NSW’s Fleet Replacement Program 2024/25.

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