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Following a number of deaths due to this phenomenon, KAZEEM BIRIOWO examines how antimicrobial resistance has become an increasing concern in Nigeria, and how the Nigerian government, working with global health organisations, can reduce the scourge. Antimicrobial resistance (AMR) is a global health threat that has been described as a “silent tsunami” by the World Health Organisation (WHO). AMR is when bacteria, viruses, fungi, and parasites change over time and no longer respond to medicines used to treat them. This makes infections harder to treat and increases the risk of disease spread, severe illness, disability, and death. AMR is a natural process, but human activity, such as the misuse and overuse of antimicrobials, accelerates its emergence and spread. Microorganisms that develop resistance to antimicrobials are sometimes called “superbugs”. AMR affects all countries, but Africa is likely to bear the heaviest burden. The burden of AMR is felt disproportionately in low- and middle-income countries, including Nigeria, where the healthcare system is already overburdened. AMR represents a global challenge as 4.95 million people who died in 2019 suffered from drug-resistant infections. AMR directly caused 1.27 million of those deaths and one in five of those deaths occurred among children under five years old. In the GBD region of Western Sub-Saharan Africa, Nigeria has the seventh highest age-standardised mortality across 19 countries Deadly effects of AMR There are several victims of AMR in Nigeria, some of whom are no longer alive. Those who Nigerian Tribune spoke with were comfortable with just their surnames being used. Mrs Adebayo, a 35-year-old mother of two, knows firsthand the devastating effects of AMR. Her seven-year-old son, Tunde, was diagnosed with pneumonia and was treated with antibiotics. However, the antibiotics proved ineffective and Tunde’s condition worsened. He was eventually diagnosed with a multidrug-resistant form of pneumonia which required more expensive antibiotics. “We were devastated when we found out that the antibiotics were not working,” Mrs Adebayo said. “We had to sell our belongings to afford the more expensive antibiotics. It was a very difficult time for us.” Similarly, Mr Okoro, a 42-year-old businessman, also has a personal experience with AMR. His 65-year-old mother was diagnosed with a urinary tract infection and was treated with antibiotics. However, the antibiotics were ineffective, and her condition worsened. She eventually died from complications related to the infection. “The death of my mother was a devastating blow to our family,” Mr Okoro said. “We were not aware of the risks associated with AMR and we did not know how to prevent it. We hope that our story can serve as a warning to others and encourage them to take action to prevent AMR.” Miss Chukwu, a 28-year-old nurse, has seen the devastating effects of AMR almost on a daily basis. She works in a hospital in Lagos, where she has seen many patients die from infections that were resistant to antibiotics. “It is heartbreaking to see patients die from infections that could have been treated with antibiotics,” Miss Chukwu said. “We need to do more to prevent AMR and ensure that antibiotics are used responsibly.” Causes and consequences of AMR in Nigeria According to the WHO, the causes of AMR in Nigeria are multifaceted and interconnected. Some of the key causes include misuse and overuse of antibiotics which are major drivers of AMR. In Nigeria, antibiotics are often prescribed inappropriately and patients often demand antibiotics for viral infections, which do not respond to antibiotics. Also lack of National Antibiotic Guidelines in Nigeria contributes to the misuse of antibiotics. Healthcare professionals often rely on personal experience and judgment when prescribing antibiotics rather than following evidence-based guidelines. General awareness and understanding of AMR in Nigeria is poor. Many healthcare professionals and the general public are not aware of the risks associated with AMR which contributes to the misuse and overuse of antibiotics. Inadequate infection control measures in Nigerian hospitals contribute to the spread of microbes, including resistant strains. Poor hygiene practices, inadequate use of personal protective equipment and lack of sterilisation of medical equipment are common in many Nigerian hospitals. The consequences of AMR in Nigeria are severe and far-reaching. Some of the key consequences include, increased morbidity and mortality. AMR poses a risk of increased morbidity and mortality, particularly in low- and middle-income countries like Nigeria. The economic burden of AMR is also substantial as a study published in the Journal of Pharmaceutical Policy and Practice estimated that the economic burden of AMR in Nigeria could be as high as $1.3 billion annually. According to the study, “AMR reduces the effectiveness of antibiotics, making it challenging to treat infections. This can lead to prolonged hospital stays, increased healthcare costs, and increased mortality. “AMR increases the risk of infections, particularly in vulnerable populations such as the elderly, young children, and people with compromised immune systems.” State of AMR in Nigeria Nigeria, with a population of over 200 million people, is faced with the burden of poverty and poor environmental conditions, such as lack of potable water and sanitation, and inadequate infection control. These factors are crucial in the spread of microbes, including resistant strains. According to the Institute for Health Metrics and Evaluation (IHME), University of Washington, Nigeria had an estimated 627,000 deaths attributable to AMR in 2019, which is the highest number of deaths in Africa. The IHME also estimated that the mortality rate due to AMR in Nigeria was 335.6 deaths per 100,000 population in 2019. Urgent need to tackle AMR Dr John Oladapo, a consultant microbiologist at the Lagos University Teaching Hospital (LUTH), emphasized the urgent need to address the growing burden of AMR in Nigeria. “AMR is a ticking time bomb in Nigeria,” Dr Oladapo said. “We need to take immediate action to address the root causes of AMR, including the misuse and overuse of antibiotics, poor infection control practices, and lack of awareness about AMR.” Dr Adebiwale Akintayo, a public health expert at the University of Ibadan, emphasized the need for a multifaceted approach to address AMR in Nigeria. “We need to adopt a comprehensive approach to address AMR in Nigeria,” Dr Akintayo said. “This includes improving infection control practices, promoting responsible use of antibiotics, and enhancing awareness and understanding of AMR among healthcare professionals and the general public.” Dr Eyitope Ogunbodede, a professor of microbiology at the Obafemi Awolowo University (OAU), emphasized the need for research and development of new antibiotics to address the growing problem of AMR. “We need to invest in research and development of new antibiotics to address the growing problem of AMR. “We also need to improve our surveillance systems to monitor the spread of AMR and develop effective strategies to prevent it,” he said. FG’s action plan Recently, the Federal Government launched the National Action Plan on Antimicrobial Resistance (AMR NAP-2.0). The Coordinating Minister of Health and Social Welfare, Professor Muhammad Ali Pate, said the launch of AMR NAP-2.0 came at a time when the global community, through platforms like the 2024 United Nations General Assembly (UNGA), had committed to renewed and urgent action against AMR. He said in 2017, Nigeria made significant strides by launching its first National Action Plan on AMR, adding “We recognised that a multisectoral, one health approach-integrating human, animal, and environmental health-was essential in confronting AMR.” The minister also disclosed that the Federal Government is committed to integrating genomic technologies into all aspects of the work, noting that a plan has been laid out to build capacity for genomic sequencing and surveillance, as well as improving response to emerging infections and advancing vaccine development. The Director General of the Nigeria Centre for Disease Control and Prevention (NCDC), Dr Jide Idris, said the second AMR National Action Plan is a comprehensive five-year strategy designed to combat antimicrobial resistance in Nigeria, adding that the NCDC leads the Antimicrobial Resistance Coordination Committee (AMRCC) to drive the implementation of the plan’s priority actions. Co- chair of the national AMR Technical Working Group, Professor Kabiru Junaid, said it will cost a total of $77.6 million to implement all the strategic objectives of the AMR National Action Plan. The Minister of Agriculture and Food Security, Sen. Abubakar Kyari, said his ministry is committed to the implementation of the activities of the action plan. The Minister of Environment, Mallam Balarabe Abbas Lawal, speaking through the Director, Department of Pollution Control and Environmental Health, Bahijjahtu Abubakar, said effective implementation of the plan will improve the country’s strategies in addressing AMR and strengthening surveillance in the environment sector, livestock and healthcare settings, while promoting sustainable standard practices that ensures food security, protection of the environment and human health. WHO’s role in supporting AMR efforts WHO has been a key technical partner in developing AMR NAP-2.0, providing guidance on global best practices and supporting the Federal Government in aligning its strategies with the Global Action Plan on AMR. To improve the national efforts to control the impact of AMR, the ministry launched the AMR NAP 2.0, which is a revision of the national action plan on AMR adopted in 2017. With the expiration of the AMR NAP-1.0 (2017-2022), an assessment of its implementation revealed key gaps and challenges, with only a 44 percent completion rate. The assessment highlighted weak involvement from sectors such as environment, plant, food, aquaculture, agriculture, and relevant human health sectors in the implementation of priority activities. Additionally, NAP-1.0 was not costed and lacked specific milestones and targets. In response, the Government of Nigeria, through the Federal Ministry of Health and NCDC, requested WHO’s support in developing NAP-2.0 (2024-2028) and providing strategic guidance for the AMR Coordination Committee to develop the plan based on the AMR Global Action Plan, WHO manual for NAP Development, WHO implementation handbook for NAPs on AMR, and the People-cantered approach to addressing antimicrobial resistance in human health. This story is produced for the Media-EIS Fellowship Programme, a collaborative partnership among the Nigeria Centre for Disease Control and Prevention(NCDC), the USAID-funded Breakthrough ACTION Nigeria and the African Field Epidemiology Network(AFENET) Get real-time news updates from Tribune Online! Follow us on WhatsApp for breaking news, exclusive stories and interviews, and much more. Join our WhatsApp Channel nowTrudeau told Trump Americans would also suffer if tariffs are imposed, a Canadian minister says

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Earlier today, Twitchy reported about how the Never Trumpers at The Bulwark were twisting themselves into pretzels trying to find a way to blame Donald Trump for Joe Biden issuing a blanket pardon for his son Hunter . They were making the case that Trump's 'politicized DOJ' would have made life a nightmare for the Biden family, neglecting the fact, of course, that it was Hunter's criminal activity that was actually responsible for that nightmare. Apparently, irony is an alien concept The Bulwark as well, evidenced by their claim that it would be Trump's DOJ that was 'politicized,' not the current one under Merrick Garland who has conducted corrupt lawfare against Trump, not to mention parents and Christian Americans, for the past four years. But if you thought that would be the only way that the journos would try to blame Trump, you don't know the dead legacy media. They will try to pin anything on Trump, even the fact that the McRib is not available year-round. Let's check in on S.E. Cupp of CNN to see what mental gymnastics she can come up with to pin the Hunter pardon on Trump, shall we? It doesn’t get said enough, but Trump’s enduring legacy will be convincing BOTH parties to lower the bar, and that possessing moral authority on anything is no longer a currency that matters. https://t.co/f9hVwwIdEc Ahh, there it is. There's the cope we love to see. Get it, America? It's Trump's fault because everything is Trump's fault. In this case, he 'lowered the bar' for everyone in terms of 'moral authority.' Has Cupp ever heard of Bill Clinton, we wonder? Whatever she was selling, Twitter wasn't buying. Bill Clinton got re-elected after using an intern as his personal Oval Office humidor and lying about it under oath. pic.twitter.com/fgpwckABK3 They conveniently like to forget about him. And not just with Monica Lewinsky. They like to forget about all of the sexual assault charges too. Way to find yet another way to blame Trump for something! https://t.co/Wer8Cm5iWM pic.twitter.com/44pN3BpCBC If she earns a few more, she gets a free sandwich at Blimpy's. Scumbag father pardons scumbag son for crimes unknown for a ten-year period of time and it’s someone else’s fault? lol You are unrecognizable and a shell of your former self. https://t.co/F6hHFXBj2e Never Trumpers truly are the worst. At least lifelong leftists have always been Marxists. The Never Trumpers just go with whatever political stance will garner them a paycheck. I can't believe Trump made Joe pardon Hunter. https://t.co/YqEazs0vM9 If Democrats still held the House, they'd probably try to impeach him for that too. Yes, Trump -- who didn't pardon any of his family despite the threat of lawfare hanging over them -- is the reason Biden pardoned his criminal son going back to before Trump even ran for president. https://t.co/HV4YGtYb50 Shh. Don't confuse Cupp with history and facts. It messes up her narrative. Biden has never once needed anyone's assistance in lowering the bar of moral behavior. Not once, even in the decades and decades of elected official status before Trump became president. https://t.co/nlsCrNOwHl During the past four years, the myth of 'kind, old Uncle Joe' was completely exposed for the lie it has always been. I’ll never forgive Trump for making Joe be a terrible person. 😡 He was such a fine, upstanding man when he ruined a trucker's life because of a car accident. And then when he forced Hunter into a suit for a photo opp in the hospital while the young boy was still being treated for traumatic injuries. This is disgusting. This continued lie that, “Everything was great and then Trump came along!” is why people trust Trump more than people like this. https://t.co/Io23CYhiuM This is true. But, to be fair, trusting someone at a higher level than a CNN hack is a pretty low bar. We’re at the point in the Hunter Biden pardon news cycle where there is a copium shortage. These media/establishment industrial complex takes are WILD. Keep em coming https://t.co/Ywyr8edInU pic.twitter.com/y7N9ZNmPJQ Do you hear yourself right now? We can assure you that she does not, in fact, hear herself. Lowering the bar you say? pic.twitter.com/z8BjpW7Eyx We would say that this reply wins a cigar ... but that would be gross. You: It's Trump's fault that Biden pardoned his son. I used to think some modicum of self respect would keep you from becoming...whatever this is, but I was wrong. Don't forget to pick up your $20 off of the nightstand on the way out. The correct term that applies here is 'presstitute.' Trump was playing 64,000D chess by making the Biden family commit international money laundering crimes in 2014 https://t.co/6WP4op3Xd1 Man, Trump is just an evil genius, isn't he? Please specify the precise federal crimes that Trump made Hunter Biden commit in 2014. https://t.co/YGvdXCwv4H Joe Biden pardoning his son, whose criminal acts he is complicit in and started long before Trump even ran for office, is somehow Trump's fault. Never change, guys. You're doing great. https://t.co/QrGEx7lXb8 And they wonder why Elon Musk declared them dead on Election Night . https://t.co/rxUYXgRz0S pic.twitter.com/TWoxHraN3T Say it with us, everyone: 'What brain?' “Biden’s actions are Trump’s fault” is the petulant cry of a demented toddler Get help https://t.co/F50HOVijxd Petulant, demented toddlers. Yep. That tracks. But S.E. Cupp will never get help because she has no self-awareness. She has no idea how galactically stupid she sounds when saying such things. That's OK. Let her cook. It just gives us more fuel to laugh at her and everyone like her.

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Former prime minister Gordon Brown and Scottish First Minister John Swinney were among those who remembered a “giant of a man” during a memorial service for Alex Salmond. Tributes were paid to the former Scottish first minister, who died suddenly in North Macedonia in October at the age of 69. A private family funeral has already taken place, with Saturday’s memorial service in Edinburgh held to celebrate his love of Scotland and his commitment to the cause of independence. A rift between her and Mr Salmond – who she had previously described as her mentor – developed during her term as SNP leader. Ms Sturgeon attended the funeral of Scottish comedian Janey Godley in Glasgow on Saturday morning. Her successor, Mr Swinney, was met with boos as he arrived at the service – held on St Andrew’s Day – with at least one person in the crowd outside on the Royal Mile shouting “traitor”. He helped found and went on to lead another pro-independence party, Alba, with Kenny MacAskill, a long-time friend who served as justice secretary in Holyrood under Mr Salmond. Mr MacAskill, now the acting Alba leader, told the congregation – which included Mr Salmond’s widow Moira as well as Scottish Labour leader Anas Sarwar, former Labour first minister Henry McLeish and Scottish Conservative leader Russell Findlay – that Mr Salmond had been a “giant of man”. Mr MacAskill, who quit the SNP to join Alba, hailed Mr Salmond as “an inspiration, a political genius” and being “most of all a man who had the cause of independence burned into his heart and seared in his soul”. He added: “Those of us who share his dream must conclude that journey on his behalf. That’s the legacy he’d expect and the duty we owe him.” Recalling Mr Salmond’s words from when he stood down as first minister that “the dream shall never die”, Mr MacAskill concluded his address with the words: “Your dream shall be delivered.” Former Conservative Brexit minister and long-time friend of Mr Salmond, David Davis, gave a reading as did former Scottish government minister SNP MSP Fergus Ewing. Scottish rock duo the Proclaimers were applauded for their performance of Cap in Hand – a pro-independence song which features the line “I can’t understand why we let someone else rule our land, cap in hand”. Brothers Craig and Charlie Reid said: “We’re going to do this for Alex, with love and respect and eternal gratitude for everything you did for our country.” While she said he had been “the top man in Scotland”, he had “always made time for his family”, recalling how he phoned her brother on his birthday – the day after the Scottish independence referendum in 2014 – to apologise for not posting a card “as he’d been busy”, before telling them he would “resigning in 10 minutes”. She told the congregation: “As his family, we always felt loved no matter how far away he was or the time that passed before we saw him next. “We always knew he was standing up for our country, and for that we were grateful.” “Uncle Alex passing means a great loss for many. A loss of Scotland’s voice on the international stage. A loss of integrity in Scottish politics. And a great loss to Scotland’s independence movement. “As a family it is likely a loss we will never get over.” He told how Mr Salmond took the SNP from being “a fringe act trying to get onto the main stage” to a party of government. “In Scottish politics, his success was both spectacular and unrivalled,” Mr Hamilton said. “History will certainly remember him as a man of talent, charisma and substance. But also as a political leader of courage, vision and intelligence. “He dared to dream. And so should we.” As the service finished the crowd gathered outside applauded and chanted “Alex, Alex” before singing Flower Of Scotland.

Baijiayun was honored with the title of "Exclusive Member Unit" by the Beijing Educational Informationization Industry Alliance.F1 Don't miss out on the headlines from F1. Followed categories will be added to My News. The guillotine has fallen on Sergio Perez. Red Bull is reportedly set to officially cut Sergio Perez following a meeting of the team’s shareholders next week — giving the Mexican driver one final ride at the Abu Dhabi Grand Prix this weekend. The year has been a nightmare for Perez, who will finish eighth in the world championship despite teammate Max Verstappen fending off Lando Norris to defend his crown. Perez has been made a laughing stock in recent months. Not since Michael Schumacher blew his teammate Jos Verstappen away in 1994 has a driver finished so far below a championship-winning teammate. He signed a contract extension — through to the end of the 2026 season — earlier this year after Daniel Ricciardo ruined what was rumoured to be a plot from Red Bull boss Christian Horner to get the Australian into Perez’s seat. Every F1 qualifying session and race LIVE in 4K on Kayo. New to Kayo? Get your first month for just $1. Limited time offer. According to ESPN , Red Bull senior figures have made the decision that enough is enough after watching Perez cost the team the constructor’s championship. The report claims Perez will likely still have a role with the team because the contract extension he signed earlier this year came with some guarantees. The contract was cleared with the Contract Recognition Board, leading to speculation sacking Perez could cost the team $10m to buy out his deal. The decision to cut Perez will send shockwaves around the sport with the team now having the difficult decision of finding the best option to replace him. VCARB driver Yuki Tsunoda has had an impressive second half of the year for the Red Bull junior operation, but Kiwi Liam Lawson has put a strong case forward since he replaced Ricciardo. According to motorsport.com , no final decision has been made — but the two VCARB drivers are the only options the team is considering. It makes next week’s final testing event in Abu Dhabi a shootout between the pair. Max Verstappen has ruined Sergio Perez’s career. Photo by Mark Thompson/Getty Images. That will then leave a vacant seat at VCARB with Red Bull again reportedly likely to promote from within its junior nursery of rising stars. According to ESPN, Formula 2 driver Isack Hadjar will likely be the one promoted to join VCARB. Red Bull product Franco Colapinto, who drove in his rookie season for Williams in 2024, looked like a strong candidate to join the Red Bull junior team, but senior Red Bull officials have reportedly gone cold on that option. Horner was diplomatic when speaking after Perez failed to finish Monday morning’s Qatar Grand Prix. It was the sixth time this season that Pérez had not scored a point . Horner said Pérez was “old enough and wise enough to know what the situation is”. “I’m going to let Checo (Pérez) come to his own conclusions, nobody’s forcing him one way or another,” he said, per ESPN. “It’s not a nice situation for him to obviously be in.” He went on to say: “Look, Checo has had a very tough year. “Obviously the points table are what they are. We’re very much focused on really supporting him to the chequered flag in Abu Dhabi, and then obviously it’s not an enjoyable situation for Checo, being in this position with speculation every week. It has been a turbulent year for Red Bull and Visa Cash App RB. Photo by Mark Thompson / GETTY IMAGES NORTH AMERICA. “He’s old enough and wise enough to know what the situation is, and yeah, let’s see where we are after Abu Dhabi.” When asked what he would do if Pérez wanted to stay put at Red Bull after next week’s season-ending Abu Dhabi Grand Prix, Horner said he would wait until the end of the weekend to see where the team was placed. It seems Perez’s failures at last month’s Las Vegas Grand Prix also lost him plenty of support — including from senior advisor Helmut Marko. “We have to have two drivers who finish in the points,” Marko told DAZN at the time. “Max is more than 200 points ahead of Sergio [in the driver standings]. For our employees, it is a disappointment because they will not receive their bonuses, as they depend on our position in the Constructors’ Championship.” Marko had essentially let the cat out of the bag on Monday, already speculating about Perez’s replacement. Marko told ViaPlay on Monday the team will make decisions next week. “There is a meeting Monday after Abu Dhabi,” he said. “All the major people are there, all of the shareholders, and there a decision will be done. “We always — or most of the time — brought our own drivers through the Red Bull program and I think it’s a philosophical decision: do we stick to that? And what I got from the shareholders is it will be in this direction.” More Coverage ‘Lost all respect’: Max gives rival both barrels Matthew Sullivan Star’s blunt admission after AFL scandal Originally published as Bombshell Red Bull report sends shockwaves across Formula 1 More related stories F1 Red Bull ready to swing the axe after nightmare year The guillotine has fallen at Red Bull with the world champion outfit set to transform what the grid looks like in 2025. Read more F1 ‘Bitter’ figure behind $23m Schumacher plot Eye-opening details behind the plot to blackmail F1 legend Michael Schumacher and his family have been revealed. Read more

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