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Health Economics Outcomes Research (HEOR) Services Market Size: Strong Growth Ahead (2024-2032)

Russia's deputy U.N. ambassador said on Wednesday any decision by President-elect Donald Trump's incoming administration to cut support for Ukraine would be a "death sentence" for the Ukrainian army, while accusing Kyiv of trying to drag NATO countries into direct conflict with Russia in the meantime. Speaking to the U.N. Security Council, Dmitry Polyanskiy accused the outgoing administration of U.S. President Joe Biden of trying through its increased support to Ukraine to create a "mess, both in Russia and with the new team in the White House." Polyanskiy said Ukrainian President Volodymyr Zelenskyy was terrified of the return of Trump in January, and had reason to be so.

CLEMSON, S.C. (AP) — Clemson reserve guard Trent Howard will miss the 12th-ranked Tigers game with No. 16 South Carolina after tearing the ACL in his left knee at practice this week. Tigers coach Dabo Swinney announced Howard's injury Wednesday. The 6-foot-3, 295-pound fifth-year graduate has been a backup much of the season, but had to step into a starter's role due to injuries along Clemson's offensive line. “My heart breaks for him,” Swinney said. Howard came in on the second snap in a 24-20 win at Pitt two games ago when lineman Elyjah Thurmon was hurt on the first play. Thurmon had an ankle injury that required surgery and will not return this season. Howard got his fourth career start last Saturday in a 51-14 win over The Citadel. and was in line for another if injured starter Marcus Tate was unable to go after missing the past three games. Howard was listed as a backup at both right and left guard on this week's depth chart. The Tigers (9-2) face the rival Gamecocks (8-3) on Saturday. —- Get poll alerts and updates on the AP Top 25 throughout the season. Sign up here . AP college football: https://apnews.com/hub/ap-top-25-college-football-poll and https://apnews.com/hub/college-footballMuhammad Arshad, a seasoned finance professional, barely had time to celebrate when his company received a multi-million-rupee order for meat exports – the biggest deal of his career. As the company’s finance and operation manager, he was thrilled with the opportunity and quickly mobilised his staff. But what followed was a crash course in the harsh realities of Pakistan's export infrastructure. Securing enough livestock to fulfill the order became a major challenge first; he had no option but to rely on traditional, often chaotic animal markets due to Pakistan's lack of organised farming infrastructure. While Arshad managed to gather the necessary animals despite the challenges, his problems, unfortunately, did not just end there. “When we added up the actual costs of transportation and everything else, we realised that the profit would be much lower than expected,” Arshad shared. “So we had to stop exports in January 2024.” Untapped potential Though the 2023-24 fiscal year saw Pakistan’s meat exports to the Middle East soar as high as $430.89 Million, the country has yet to harvest the sector’s full potential. The exports to the region can amount to $3 billion, according to the Dr M. Akram, the Husbandry Commissioner at the Ministry of Food Security. “They could be even higher, if issues of supply chain, farms, standards and others are addressed properly,” he said. The struggle Arshad’s company faced is not isolated incident; it reflects a broader set of challenges that are hindering Pakistan’s food export sector from reaching its real potential. Federation of Pakistan Chamber of Commerce and Industry (FPCCI) Chairman Karim Aziz Malik pointed out that several food exporters have had to cut back on exports lately. Rising business costs and other factors are hurting their profit margins, he explained. “The export businesses will struggle if the infrastructure doesn’t improve. Unclear rules and regulations, along with poor infrastructure, could really slow things down.” The 2023-24 boom However, while the challenges faced by businesses might make someone think things are looking bleak, there is still a surprise in store – Pakistan’s food exports are booming like never before. In 2023-24, Pakistan’s food exports saw historical high surge, hitting a staggering $8 billion, a massive 37 per cent increase over the previous year. Astonishingly, the country exported a whopping $2.36 billion worth of food products in the first four months of this year by itself, according to Pakistan Bureau of Statistics (PBS). Rice alone brought in whopping $4 billion in 2023-24. The year’s remarkable figures, driven by demand from diverse markets in Europe, China the Middle East and Africa, indicate a promising future for Pakistan’s food exports. Particularly exciting to see are Pakistani sesame seeds gaining popularity in China and other parts of the world with the country’s growing presence in the Middle East, Western Africa and Europe. Nevertheless, it is paradoxical that despite ongoing issues and some dissatisfaction among exporters, food exports reached a record high. Several key factors played a role in this unexpected success story, including strategic government initiatives and a favourable marketplace, though threats exist that could potentially disrupt the growth momentum and prevent the industry from reaching its potential if issues on the ground are not addressed timely. According to one commerce ministry official, to boost the exports further, the National Logistic Cell has improved its network for accessing CARS and Russian market. “Agro products are reaching to CARS, Afghanistan and Russia through this improved network connection,” he said. The government is also trying to explore a new trade route via Russia to Eastern European countries. “[Besides other steps] we opted for effective marketing strategies to boost exports as well,” said Athar Khokar, the Director General Agro-Food at the Trade Development Authority of Pakistan (TDAP). TDAP facilitated the participation of exporters in international exhibitions – last year, 164 exporters participated in 17 exhibitions in different parts of the world. It also facilitated visits of exporters to different parts of the world and created opportunities where buyers in large numbers could interact with Pakistani exporters. Documents also reveal efforts of the TDAP and the government for product development through seminars and training in different parts of the country to meet criteria for exports. The TDAP senior official noted that some new countries for food export are being targeted after analysing their market needs. For example, Indonesia, Philippines, African Countries, EU, KSA, and Central Asia are being focused as destinations for rice, while fisheries exports are being made to China, Thailand, EU, US and UK, he said. An official in the commerce ministry, on condition of anonymity, said special marketing initiatives were launched in China for sesame and the seed is now being exported to China, EU and South Korea. How the opportunity arose? With all those efforts, it is important to acknowledge the impact of international factors and growing conditions as well. First, India’s decision to restrict some food exports to stabilise prices in their own country, along with their non-compliance with international standards and the restrictions imposed by EU on their some products, unintentionally created an opportunity for Pakistani food products like rice and onion to gain a larger share of the global market. Detection of pesticide residues in Indian products were reported as Indian shipments did not comply with the maximum residue limits (MRLs) — the permissible thresholds for pesticides — set by the EU. India’s shipments had a relatively higher non-compliance rate compared to that of Pakistan, two years back. In addition, the crisis in Ukraine also caused interruption in supplies from that region that created an opportunity for the surge in Pakistani agro-food exports. Internally, production in Pakistan this time was far better in rice and other products too. The US Department of Agriculture (USDA) forecasted that Pakistan's milled rice production will increase 64 per cent to nine million metric tonnes (MT) in 2023–24. Fortunately, the actual production was slightly more than that estimate. Can the success be sustained? Yet, people who closely follow Pakistan’s exports are skeptical about whether the country can sustain the recent growth. How Pakistan can reach its ambitious goal of $25-30 billion in the next few years? The answer is not simple as India has started improving things and decided to recapture the market by lifting limitations on its food exports. T his year, rice shipments from Pakistan have triggered more alerts relating to the MRLs than those from India as well. Dr. Abid Qaiyum Suleri, a researcher on food security and development and an executive director at SDPI, said that to improve food exports, Pakistan needs better arrangements for raw materials and value added products. “We don’t have such arrangements here. Also, the government should allow agents and also focus on quality and quantity to meet international standards.” Experts say it will take major effort to develop the infrastructure for food exports. According to them, this means Pakistan is far from reaching its full potential in food exports. Some of the experts think that India’s decision to remove cap on its rice exports could significantly reduce Pakistan’s current exports. Karim Aziz Malik asked, “Can Pakistan sustain its $4 billion in rice exports? We can not compete with India’s non-basmati rice as it is $100 per tonne cheaper than ours. Now they have decided to increase export of the rice. Is it difficult to predict as what effect it would have on our total rice export?” According to him Pakistan cannot hope for the best until prices of electricity and fuel are reduced for consumers in the country, interest rate is brought down to single digit, and basic issues are addressed, including tax structure for exporters. Analysts maintain that at the movement, Pakistan cannot ignore conditions imposed by IMF and decisions on issues like tax relaxation are unlikely. Moreover, the Pakistani export sector is facing long-standing challenges – such as effective supply chain, storage facilities, farming and technology and others – that are hindering its growth. Pakistan has been a top rice exporter for decades but even its rice industry faces basic issues. This raises questions the state of other export sectors. Rice Exporters Association of Pakistan (REAP) Senior Vice Chairman Muhammad Jawed Jilani said they have recently discussed some issues with TDAP, whose officials vowed to address their difficulties. In November a delegation from REAP, met with TDAP officials, raising concerns about export challenges, particularly related to storage, infrastructure, logistics and supply chain inefficiencies. The rice exporters also demand streamlining export processes and role of technology for competitiveness and enhancing quality. TDAP’s DG Agro-Food, when asked about REAP’s recommendations, said, “We are planning to involve all major stakeholders linked to logistic network for improving our valuechain”. However, experts agree that the problems REAP raised have been around for decades and should have should have been fixed a long time ago. They maintain that successful exports need an established industry and investor-friendly environment. The situation in the rice industry is a sign that other parts of the export sector could be in even worse shape. An exporter on condition of anonmity, shared that besides other issues sometime operational efficiency also become a problem. “To reach the real potential in agro-food export, we need modern farming practices and digital tools besides addressing the basic issues in the sector”, he said. The concerned officials in the Ministry of Commerce were not available to comment on how the government plans to address the basic issues in food export. On future activities for promotion of Pakistani food products, TDAP’s DG Agro-Food said his organisation intends to participate in 27 major food exhibitions to showcase Pakistani products. Imdad Hussain is a freelance journalist and contributor All facts and information are the sole responsibility of the authorINDIANAPOLIS (AP) — The Indianapolis Colts defense started this season struggling. It couldn't stop the run, couldn't keep teams out of the end zone, couldn't get off the field. Now the script has flipped. Defensive coordinator Gus Bradley's group is playing stouter, holding teams — even the high-scoring Detroit Lions — largely in check long enough to give Indy a chance to win, and it's the Colts offense that has struggled. “They are playing their tails off. You don’t want them on the field a bunch and as an offense you want to be able to play complementary football,” running back Jonathan Taylor said after Sunday's 24-6 loss. “I would say specifically on offense, it sucks when you can’t help your defense out when they are fighting their tails off all game.” Indy's defense held up its end of the bargain by limiting the Lions (10-1) to 14 first-half points and allowing just 24, matching Detroit's lowest output since Week 3. The problem: Even when the Colts (5-7) did get Detroit off the field, they couldn't sustain drives or score touchdowns. Again. Anthony Richardson provided the bulk of the ground game by rushing 10 times for 61 yards, mostly early. Taylor managed just 35 yards on 11 carries and a season-high 10 penalties constantly forced the Colts to dig out from deep deficits. Part of that was by design. “We knew Jonathan Taylor was going to be the guy we needed to shut down,” Lions coach Dan Campbell said. “We did that. The quarterback runs. It got us on a couple but overall, we did what we needed to do, and we kept them out of that game." Part of it could be because of an injury-battered offensive line that has started three rookies each of the past two weeks and finished the previous game with the same three rookies. Whatever the fix, Indy needs a good solution. There is good news for Indy is that its schedule now gets substantially more manageable. After losing four of five, all to teams in playoff position and three to division leaders, Indy faces only one team with a winning record in its final five games. The most recent time the Colts played a team with a losing mark, Richardson rallied them past the New York Jets 28-27. But Colts coach Shane Steichen knows that's not the answer. The Colts must get this offense righted now. “We’ve got to get that figured out. We’ve got to get him going on the ground,” Steichen said when asked about Taylor, who has 92 yards on his past 35 carries. “We’ll look at the offensive line. We’ll look at everything." Pass rush. Pro Bowl DT DeForest Buckner's presence certainly has been felt since he returned from a sprained ankle Oct. 27. In those past five games, the Colts have had 14 sacks, including three of Jared Goff on Sunday. Penalties. The Colts have had one of the cleanest operations in the league most of this season. Sunday was an anomaly, but one that can't merely be written off. WR Michael Pittman Jr. The five-year veteran is one of the league's toughest guys, but playing through a back injury appeared to take its toll on Pittman's productivity. Since sitting out in Week 10, Pittman has 11 receptions for 142 yards including six for 96 yards, his second-highest total of the season, Sunday. Tight ends. Each week the Colts want their tight ends to make an impact. And each week, they seem to fail. It happened again Sunday when Drew Ogletree dropped a TD pass that would have given Indy a 10-7 lead. Instead, Indy settled for a field goal and a 7-6 deficit. Through 12 games, Indy's tight ends have a total of 26 catches, 299 yards and two TDs. That's just not good enough in a league where versatile, productive tight ends increasingly signal success. Pittman and WR Josh Downs both returned to the game after leaving briefly with shoulder injuries. WR Ashton Dulin did not return after hurting his foot in the second half. But the bigger questions come on the offensive line. LT Bernhard Raimann (knee) was inactive Sunday, and rookie center Tanor Bortolini entered the concussion protocol Monday. Bortolini was one of three rookie starters the past two weeks, replacing Pro Bowler Ryan Kelly who is on injured reserve. 55.88 — Indy has scored touchdowns on 55.88% of its red zone trips this season. While it puts it near the middle of the NFL, it's cost the Colts multiple wins. Richardson needs to rebound from this latest 11 of 28 performance and show he can lead the Colts to victories week after week. He'll get plenty of chances over the season's final month, starting with next week's game at the New England Patriots. AP NFL: https://apnews.com/hub/nflInclement weather leads to multi crashes near Ridgetown

Back in 2017, early into Donald Trump’s first term as US President, China’s Communist Party leader Xi Jinping turned up to the Davos world economic forum and told the assembled corporate heavyweights and global leaders that China embraced globalisation and was continuing to ‘open up’ to foreign businesses and capital. Seven years on, he’s at the G20 leaders meeting in Rio with the same old script. As Australia navigates a dangerous world and fracturing globalised economy, though, one thing we should not do inadvertently or actively is join a camp that leads to greater dependency on whoever is in power in Beijing. Debates about Australian dependency on the US with the return of Trump are important, but they should not drown out the obvious dangers from handing Xi Jinping more power to punish and damage Australia’s economic and national security and future prosperity. Xi lied at Davos in 2017. Under his rule, China has pursued a ruthless path towards what Xi calls "dual circulation", a geo-economic strategy that seeks to make China less dependent on other economies while making others more dependent on China. In the years since, Xi has presided over China’s slow strangulation of foreign businesses in China. He has provided large subsidies to grow Chinese industrial capacity to control global supply chains from renewables to semiconductors and electric vehicles. In many ways this has been a success: Chinese EV and solar panel producers now have so much excess production capacity that they can flood other nations’ markets and undercut any opposition. This has already destroyed much of the rest of the world’s solar panel and other renewable energy industries. It is now threatening the future of European car companies and is part of an emerging industrial crisis in Germany affecting foundational companies like VW. While China is still behind the curve in producing advanced semiconductors, massive government funding to local firms is helping them make less advanced chips at scale. And China also dominates supply chains for EVs, batteries, renewables and semiconductor production. It has virtual monopoly control of global gallium and germanium, for example, minerals used in semiconductors, renewables and military applications. And Xi Jinping has built new laws and regulations that give his government the power to restrict supply to any companies or countries he wants to punish. Chinese producers are being encouraged by Beijing to bail out China’s stuttering domestic economy by exporting. China’s leaders also want them to build dominant global market shares, kill foreign competition and offload excess capacity by flooding markets from the EU to Africa, south-east Asia and places like Australia – any place that is open to this economic strategy provides an opportunity. At the same time, foreign companies in China are watching their market shares fall as Beijing promotes economic nationalism, pushing Chinese consumers to show their patriotism by buying Huawei phones and Great Wall and BYD cars, instead of foreigners’ products like Apple devices and Mercedes and Volkwagens. The status that wealthy Chinese consumers used to get from buying high-end Western companies’ products is being replaced by the rise in "patriotic" status consumers get from buying their Chinese competitors’ products instead. Huawei’s release of a trifold smartphone is a good example: Huawei’s Chinese "superfans" are angry they can’t get their hands on one because of limited supply. Meanwhile, Apple’s China sales numbers keep falling, as does BMWs, Mercedes and VWs – VW’s profit has slumped by 60 per cent. So, China’s economy is not opening up to free trade under Xi. But that hasn’t stopped him repackaging and regurgitating his 2017 Davos speech for the benefit of the G20 audience gathered in Rio this week. Faced with a return of Donald Trump to the White House and likely very large tariffs on Chinese exports to the huge US market, Xi is again wrapping himself in the mantle of free trade and open markets, telling us all he is on our side against Mr Trump’s protectionist stance. And he’s lying through his teeth again, as we all know and as we knew back in 2017. What Xi Jinping wants is to be able to pursue his highly protectionist economic strategy while everyone else opens their borders and markets for him to flood with Chinese products and lets China’s state and non-state companies buy productive assets and secure inputs China needs. In his view, that seems more likely if the countries he wants to dominate politically and economically are beacons of free trade - particularly if we’re happy to turn a blind eye to his breathtaking hypocrisy and duplicity in pursuit of a quick buck. This sounds an insane proposition for Xi to try to sell at the G20, but the more insane thing is that he seems to have a willing audience, at least, in form of Mr Albanese, backed by Australia’s free trade Treasury ideologues, cheered on by understandably self-interested groups like Australian lobster fishermen. Mr Albanese was effusive even in the carefully crafted remarks released of his chat with Xi, saying: “Let me express, as well, my appreciation for your tremendous hospitality when I visited Beijing last year, and where we have recommenced our leaders meetings.... trade is flowing more freely to the benefit of both countries and to people and businesses on both sides. We continue to explore opportunities for practical co-operation in areas of shared interest, including on our energy transition and climate change”. Who knows how gushing he was in private. From this, Xi will see this "handsome boy" who happens to be our prime minister as a willing if naive partner in advancing Chinese goals and objectives, particularly in dealing with the headwinds China is expecting from a second Trump presidency. Now is the worst time for Mr Albanese to announce that Australia is doubling down on ‘free trade’ and wants to grow trade with China. With the rise of industrial policy approaches from Brussels to Tokyo, New Delhi, Washington DC and Beijing, the rest of the world has moved emphatically from free to managed trade. And China will take ruthless advantage of us if we’re silly enough to accept Treasury’s stagnant trade policy prescriptions, resulting in Australia becoming a pawn in Beijing’s economic arm wrestles with Washington. Seeing Mr Albanese seize now as the moment to embrace free trade on the global stage is a bit like watching someone choosing to embrace and promote Communism back in the early 1990s, just after the Berlin Wall fell and the Soviet Union disintegrated. So, a tiny bit of historical memory shows us that Xi Jinping is not the saviour of free trade or the globalised economy. But he is a relentless Communist autocrat with a plan to make China less dependent on others – and the rest of us dependent on what he decides, allows and wants. Decoupling our economy from that future vision is not just wise: it’s essential for our freedom, security and success.Black Friday is almost here, and Walmart is back again with some of the hottest deals on home goods! If you need a new bedding set or high-speed blender, now's the time to shop because so many home essentials are up to 70% off. Check out some of our favorite home deals below: 1. A warm leather and amber candle that smells way more expensive than it actually is. This candle will fill your room with a warm, musky, and cozy scent that'll make you feel like you're cuddled up in a chic hotel. Promising review: "Let's just say I love this particular candle so much I have four. It has become one of my favorite scents. These candles are quality items, smell great, and are long-lasting." — Morgan Price: $5 (originally $9.78) 2. And a candle warmer lamp to go with your new candle. This uses heat, not fire, to melt the wax, making it a much safer option for those who have animals or little ones running around the house. Promising review: "I have several half-used candle jars that I loved the smell so much I didn't want to throw away. Now I can enjoy them again! I love the dimmer, adjustable height, and timer options. Also, I like the fact that it plugs into the wall and does not require batteries." — Patricia Price: $18.99 (originally $29.99) 3. A faux fur memory foam bath mat , because the bane of your existence is cold tiles on wet feet. This'll keep you nice and cozy while providing shock support from hard floors. Price: $4 4. A countertop ice machine so you don't have to invest in a fancy fridge for automatic ice cubes. You can use it anywhere from your kitchen to your office at work, and even your RV! Promising review: "I was excited to begin using this ice maker. After reading the directions, I placed it in my RV and plugged it in. I added distilled water and turned the unit on. It began humming away and, within minutes, produced its first cubes. I love the idea that the cubes are contained in a plastic basket above the water reservoir. How genius! That way, if the cubes begin to melt, the water returns to the reservoir!" — Margaret Price: $53.99 (originally $129.99; available in two colors) 5. A ceramic kitchen canister set to add a bit of pizazz to your kitchen setup (AKA, give you a designated space to put all those miscellaneous coffee cans and sugar bags that are currently crowding your counter). Price: $20 6. A surround sound bar system , because watching a suspensful movie with surround sound feels like you're in the thick of the action. This pairs with most modern TVs and even has Bluetooth capabilities! Promising review: "Amazing product for the price. This is a legit, non-paid review. I was looking for a gift for my son's birthday, and he wanted a subwoofer for his room. Well, let me tell you that the bass is awesome. If you position the speakers around the room, you are in the movie." — J Price: $89.99 (originally $199.99) 7. An eight-piece reversible comforter set so that you can add a luxurious feel to your space at a fraction of the price. This set conveniently comes in a bag, meaning it stores super easily. It comes with one comforter , one quilt, two standard comforter shams, one flat sheet, one fitted sheet, and two standard pillowcases. Price: $28 (available in sizes queen–king and in two colors) 8. A Shark IQ robot vacuum , because your daily chores add up, and anything that can help take the load off is welcome. This vacuum memorizes your home's floor plan, maneuvering around corners and furniture to get all the dust and debris that accumulates throughout the day. Plus, it holds up to 60 days of dirt! How neat is that? Price: $248 (originally $499.99) 9. A Ninja single-serve blender so that you can extract necessary nutrients and vitamins from your favorite fruits and veggies. This blends directly into an on-the-go cup, making clean up after solo smoothies and protein shakes a breeze. Price: $25 (originally $49; available in four colors) 10. A hand towel and washcloth set so that you can add a hotel feel to your WC without dropping serious coin. Price: $4+ (available in three colors and two set sizes) 11. A 12-piece silicone cooking utensil set , because that one ladle you've had since 2006? Yeah, it's due for an upgrade. This set comes with everything you need to cook or bake your favorite meals. This set includes a slotted turner, a mini turner, a solid spoon, a mini solid spoon, a spatula, a mini spatula, a whisk, a mini whisk, tongs, a silicone spoon rest, and a silicone sponge. Price: $20 (originally $58.56) 12. And a 32-piece non-stick cookware and bakeware set , just in case your kitchen is due for a total makeover. Honestly, getting these many pots, pans, baking sheets, and cooking utensils for under 100 bucks is such a steal. You'll get an 8-inch frying pan, a 10-inch frying pan, a 2-quart saucepan with a matching lid, a 2.5-quart saucepan with a matching lid, a 5.5-quart Dutch oven with a matching lid, a lasagna pan, a pizza pan, a quarter sheet pan with a gold-tone rack, a medium baking sheet, a medium silicone baking sheet, plus a slotted spoon, a mixing spoon, a spatula, a slotted spatula, a serving spoon, a pasta fork, a basting brush, a silicone spoon rest, six measuring spoons, and four measuring cups. Price: $87 (originally $198) 13. An espresso machine with a steam wand that will save you soooo much money in the long run. Think of all the cappuccinos, lattes, and macchiatos you'll be getting from the comfort of your own home and NOT from the expensive coffee shop down the street. Promising review: "This Chefman espresso machine makes rich, flavorful coffee with ease. Its sleek design and user-friendly features make it a standout choice." — Adina Price: $50 14. A digital toaster and air fryer with space to toast six slices of bread at once! You can also use this to roast a whole chicken, dehydrate kale for kale chips, bake sweet treats, and air fry with almost no oil thanks to its patented Fry Force 360° Technology. Promising review: "This air fryer is my favorite one so far. It has several presets that make it super easy to use. It comes with more than one shelf, allowing me to cook different things simultaneously. I use it to cook just about every meal for the three of us." — heather Price: $50 (originally $99) 15. A pack of adhesive shower caddies , because a bathroom upgrade can look as simple as clearing your bathtub of products that are crowding the corners. Promising review: "I was worried that the adhesive wouldn't stick well to the wall, but to my surprise, it was super easy to install and looks great! The shelves are sturdy and can hold much weight without damaging the wall. Highly recommend for anyone looking for a simple and hassle-free solution." — Monica Price: $14.99+ (originally $69.99; available 2- or 3-packs, with a towel rack, and in four colors) 16. And an over-the-toilet storage shelf since your sink deserves the same treatment! You can finally take all your skincare off your sink and place them in a spot where they're just as easy to reach. It's also a great place to store extra hand towels, TP, and candles. Promising review: "I looked at a bunch of these over-the-toilet storage units before choosing this one. I'm impressed with the overall quality and stability. It looks nice, and has helped add some organization/storage to an extremely tiny bathroom. I found the assembly pretty straightforward." — Ali Price: $46.99 (originally $199.99; available in four colors) 17. A sleek TV console to add a MCM vibe to your place without spending a fortune on actual vintage MCM pieces. Promising review: "Love the brown color. Very nice with my 58” TV. Good material. My husband was able to set up well with instructions. Very quick delivery. Stated it would come by the end of the week and ended up showing up five days early, which was very unexpected. Delivered with care." — Eva Price: $53.99+ (originally $126.99; available in two colors) 18. A 7.5-qt stand mixer if you've always wanted to enjoy the power of a "paddle attachment" but have been saving a certain stand mixer for your wedding registry. This works just as well for whipping desserts and mixing batter. Promising review: "This is the first stand mixer I bought. I absolutely love it! I can double my thick oatmeal cookie dough without my arm getting sore lol. It works great and gets to the bottom of the bowl. The bowl is very nice as well. Very sturdy. It's also light enough to store in my pantry and pull out only as needed." — Miriam Price: $79.99 (originally $169+; available in four colors and a 6.3-quart size) 19. And an arched bookcase with doors will add a super luxe, city-like feel to your home while being the perfect place to hide more unsightly things like extra cords, sewing kits, hardware boxes — you get it. Promising review: "Truly has made our space warm and inviting. Took about two hours to assemble, but the instructions are straightforward and straightforward. Highly recommend!" — Dana Price: $309.99+ (originally $419.99+; available in three colors) You, shopping for new home goods at Walmart's Black Friday Sale : Reviews have been edited for length and/or clarity. Need ingredients for all your new recipes? Shop each recipe directly through the app, or check out Walmart’s grocery selection to get veggies, meat, seafood, and more delivered right to your door.Gene Editing Market to See Rapid Expansion Over the Next Decade 2024-2032 12-14-2024 01:55 PM CET | Health & Medicine Press release from: Cognate Insights Gene Editing Market Latest Market Overview The global gene editing market is poised for substantial growth, with an estimated market size of USD 7.6 billion in 2024. This market is projected to expand at a compound annual growth rate (CAGR) of 15.4% from 2024 to 2032, reaching an estimated value of USD 26.5 billion by 2032. Gene editing technologies, such as CRISPR-Cas9, TALEN, and ZFNs, are revolutionizing the fields of biotechnology and healthcare by enabling precise modifications to DNA. The increasing demand for gene therapies, advancements in agricultural biotechnology, and the growing prevalence of genetic disorders are key factors fueling the growth of this market. The Gene Editing Market has experienced steady growth in recent years and is expected to continue expanding at a strong pace from 2024 to 2032. This analysis offers a comprehensive overview, providing valuable insights into key trends and developments within the Gene Editing industry. These findings equip business leaders with the necessary knowledge to devise more effective strategies and enhance profitability. Furthermore, the report serves as a useful resource for new and emerging businesses, helping them make informed decisions as they navigate the market and seek growth opportunities. Major Players of Gene Editing Market are: Editas Medicine (USA, Revenue: $32.5 million) Intellia Therapeutics (USA, Revenue: $44.6 million) CRISPR Therapeutics (Switzerland, Revenue: $313.3 million) Sangamo Therapeutics (USA, Revenue: $111.5 million) Beam Therapeutics (USA, Revenue: $17.9 million) Get Latest PDF Sample Report @ https://www.cognateinsights.com/request-sample/gene-editing-market-research Our Report covers global as well as regional markets and provides an in-depth analysis of the overall growth prospects of the market. Global market trend analysis including historical data, estimates to 2024, and compound annual growth rate (CAGR) forecast to 2032 is given based on qualitative and quantitative analysis of the market segments involving economic and non-economic factors. Furthermore, it reveals the comprehensive competitive landscape of the global market, the current and future market prospects of the industry, and the growth opportunities and drivers as well as challenges and constraints in emerging and emerging markets. Global Gene Editing Market Landscape and Future Pathways: North America: United States Canada Europe: Germany France U.K. Italy Russia Asia-Pacific: China Japan South Korea India Australia China Taiwan Indonesia Thailand Malaysia Latin America: Mexico Brazil Argentina Korea Colombia Middle East & Africa: Turkey Saudi Arabia UAE Korea Speak to Our Analyst for A Discussion on The Above Findings, And Ask for A Discount on The Report @ https://www.cognateinsights.com/check-discount/gene-editing-market-research Key drivers and challenges influencing the Gene Editing market: Regional Analysis: The report involves examining the Gene Editing market at a regional or national level. Report analyses regional factors such as government incentives, infrastructure development, economic conditions, and consumer behaviour to identify variations and opportunities within different markets. Market Projections: Report covers the gathered data and analysis to make future projections and forecasts for the Gene Editing market. This may include estimating market growth rates, predicting market demand, and identifying emerging trends. Company Analysis: Report covers individual Gene Editing manufacturers, suppliers, and other relevant industry players. This analysis includes studying their financial performance, market positioning, product portfolios, partnerships, and strategies. Consumer Analysis: Report covers data on consumer behaviour, preferences, and attitudes towards Gene Editing This may involve surveys, interviews, and analysis of consumer reviews and feedback from different by Application. Technology Analysis: Report covers specific technologies relevant to Gene Editing. It assesses the current state, advancements, and potential future developments in Gene Editing areas. Reason to Buy this Report: -Analysis of the impact of technological advancements on the market and the emerging trends shaping the industry in the coming years. -Examination of the regulatory and policy changes affecting the market and the implications of these changes for market participants. -Overview of the competitive landscape in the Gene Editing market, including profiles of the key players, their market share, and strategies for growth. -Identification of the major challenges facing the market, such as supply chain disruptions, environmental concerns, and changing consumer preferences, and analysis of how these challenges will affect market growth. -Evaluation of the potential of new products and applications in the market, and analysis of the investment opportunities for market participants. For In-Depth Competitive Analysis - Purchase this Report now at @ https://www.cognateinsights.com/purchase-report/gene-editing-market-research Contact Us: Cognate Insights Web: www.cognateinsights.com Email: info@cognateinsights.com Phone: +91 8424946476 About Us: We are leaders in market analytics, business research, and consulting services for Fortune 500 companies, start-ups, financial & government institutions. Since we understand the criticality of data and insights, we have associated with the top publishers and research firms all specialized in specific domains, ensuring you will receive the most reliable and up to date research data available. To be at our client's disposal whenever they need help on market research and consulting services. We also aim to be their business partners when it comes to making critical business decisions around new market entry, M&A, competitive Intelligence and strategy. This release was published on openPR.

It is fair to say that ( ) doesn't get anywhere near as much attention as the likes of ( ) or ( ). But that doesn't mean that this ASX 300 stock isn't a high-quality option with a bright future. Just ask the team at Goldman Sachs, which is tipping the billing and customer care solution provider's shares as a buy right now. What is the broker saying about the ASX 300 tech stock? Goldman was pleased with Hansen's annual general meeting update, which saw management reiterate its belief that it can continue to grow its revenue organically by 5% to 7% each year for the foreseeable future. It said: HSN's AGM update highlighted mgmt's view that +5-7% organic revenue growth is sustainable, driven by structural digital transformation tailwinds across both verticals. Per our analysis, HSN's FY25E guidance implies that sales in the core business (ex Powercloud) are accelerating to ~8% y/y in FY25E, following a trend that started in FY20A of consistent improvements in organic growth. HSN is in late-stage discussions for several large-sized contracts (some >A$30mn in TCV), which may be incremental to the +5-7% range in FY25E (and/or support an increase to the revenue growth guidance in future years). The broker also sees the recently acquired Powercloud business as a significant driver of growth in the future. Goldman believes that once its cost outs are complete, it will hit an earnings inflection. Goldman adds: Bringing forward profitability to 2H25E (vs 4Q25E) and providing detail around cost-out execution (incl. reducing headcount from 390 to 140) increases our confidence in HSN's ability to bring Powercloud's margins toward ~30% (FY27 GSe), particularly given headcount was ~50 before Powercloud's global expansion (i.e. further room to cut costs). HSN's stated ~A$27mn of annualised cost-out to date is almost 50% of Powercloud's pre-acquisition cost base and in our view implies Powercloud should be entering FY26E generating ~A$10-15mn of annualised EBITDA – a key pillar of HSN inflecting from +7% EBITDA growth in FY25E to +24% in FY26E (we sit +6% vs FY26E VA Cons.). Big returns Goldman thinks that the ASX 300 tech stock is being undervalued by the market. It explains: We believe FY26E is the appropriate year to capitalise into valuation as Powercloud moves into profitability. On this basis, HSN is trading on 9.4x EV/EBITDA (vs ~11x historical average), and is on 0.7x growth-adjusted vs 1.5x AU Tech peers. In light of this, the broker has retained its buy rating with an improved price target of $6.35. Based on its current share price of $5.57, this implies potential upside of 14% for investors. In addition, a 1.8% dividend yield is expected in FY 2025.

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Albanese – China’s ‘handsome boy’ – is becoming perfect ‘free trade’ patsyClemson left guard Trent Howard out with ACL tear for South Carolina gameMILAN — Shoppers laden with bags from Fendi, Loewe, Prada and other designer labels clog the narrow sidewalks of Milan's swankiest shopping street, bringing joy to the purveyors of high-end luxury goods this, and every, holiday season. There's even more to celebrate this year: a commercial real estate company crowned Via MonteNapoleone as the world's most expensive retail destination, displacing New York's Fifth Avenue. The latest version of American firm Cushman & Wakefield's annual global index, which ranks shopping areas based on the rent prices they command, is a sign of Via MonteNapoleone's desirability as an address for luxury ready-to-wear, jewelry and even pastry brands. A man walks past a shop Dec. 12 in Monte Napoleone street in Milan, Italy. The average rent on the Milan street surged to $2,047 per square foot, compared with $2,000 per square foot on an 11-block stretch of upper Fifth Avenue. Via MonteNapoleone's small size — less than a quarter-mile long — and walking distance to services and top cultural sites are among the street's key advantages, according to Guglielmo Miani, president of the MonteNapoleone District association. "Not everything can fit, which is a benefit," since the limited space makes the street even more exclusive and dynamic, said Miani, whose group also represents businesses on the intersecting side streets that together with Via MonteNapoleone form an area known as Milan's Fashion Quadrilateral. Women look a shop Dec. 12 in Monte Napoleone street in Milan, Italy. The biggest brands on the street make 50 million euros to 100 million euros in annual sales, Miani said, which goes a long way to paying the rent. Tiffany & Co. is preparing to take up residence on Via Montenapoleone, and longtime tenant Fendi is expanding. The MonteNapoleone District says 11 million people visited the area this year through November, but there's no way to say how many were big spenders vs. window shoppers. The average shopper on Via MonteNapoleone spent 2,500 euros per purchase between August and November — the highest average receipt in the world, according to the tax-free shopping firm Global Blue. The street is a magnet for holiday shoppers who arrive in Maseratis, Porsches and even Ferraris, the sports car's limited trunk space notwithstanding. A mannequin is seen Dec. 12 in a shop in Monte Napoleone street in Milan, Italy. Lights twinkle overhead, boutique windows feature mannequins engaged in warm scenes of holiday fun, and passersby snap photos of expertly decorated cakes in pastry shop displays. A visitor from China, Chen Xinghan, waited for a taxi with a half-dozen shopping bags lined up next to him on the sidewalk. He said he paid half the price for a luxury Fendi coat that he purchased in Milan than he would have at home. "I got a lot," Chen acknowledged. "It's a fantastic place, a good place for shopping." A man waits for a taxi Dec. 12 in Monte Napoleon street in Milan, Italy. A few store windows down, Franca Da Rold, who was visiting Milan from Belluno, an Italian city in the Dolomites mountain range, marveled at a chunky, yardslong knit scarf priced at 980 euros. "I could knit that in one hour, using 12-gauge knitting needles as thick as my fingers, and thick wool. Maximum two hours," Da Rold said, but acknowledged the brand appeal. Buildings are decorated Dec. 12 in Monte Napoleone street in Milan, Italy. Despite upper Fifth Avenue getting bumped to the No. 2 spot on the Cushman & Wakefield list, the organization that serves as the Manhattan street's guardian and chief promoter had praise for MonteNapoleone's achievement. "Milan's investment in its public realm is paying off, which is a win for their shoppers, businesses and city as a whole," said Madelyn Wils, interim president of the Fifth Avenue Association. She also expressed confidence that with new investments and a record year for sales on Fifth Avenue, "we'll be back on top in no time." The holiday season feels a little less jolly considering the amount of waste generated by gift-giving. The Environmental Protection Agency estimates the amount of household garbage in the U.S. increases by 25% between Thanksgiving and New Year's. After the decorations come down, all that waste heads to landfills, producing a significant contributor to climate change: methane gas. "Greening" the holidays is essential, and one simple tip is to think more about how sustainable the materials are in your decorations, decor, and, of course, gifts. Instead of plastics, you could opt for items that can be reused, are made of renewable materials or natural fibers that boast a smaller environmental impact in both production and durability. Due to consumers' desires for more eco-friendly goods, sustainable materials are among the biggest trends in home decor. Fortunately, there are plenty of affordable—and earth-conscious—home goods that make perfect holiday gifts. Made Trade rounded up a list of sustainable home decor trends in 2025 that offer dozens of creative options for holiday gift-giving. Each trend includes examples of great gifts for the home and advice for ensuring items are sustainably produced or can help create a more eco-friendly space. In the depths of winter's gray days, it's a real gift to see a little green, which is why indoor gardening gifts are a wonderful idea. Not only are they eco-friendly and promote sustainability—the more food you can grow yourself, the less you have to buy—they also foster an appreciation of nature and bring the natural world indoors to enjoy. Sprouting kits and microgreens require minimal amounts of space and sunlight, but a sunny, south-facing window will permit a small herb garden or leafy greens for salads. If you're not sure what kind of light your recipient has access to, go with gifting indoor grow lamps along with the plants, or pick a hardy, low-water houseplant—some can act as natural air purifiers too. When buying gifts for the home, consider what materials the items are made from and how far away they come from—not only are natural materials like rattan, jute, palm leaves, clay, organic cotton and linen, and ceramics more sustainable, but if they are being used by a local craftsperson, gifters are also saving on fossil fuels for the transportation. Plus, you're helping the local economy by supporting local craftspeople, so it's a win-win. Natural fiber pillows, sheets, blankets, and even doormats offer comfort and consideration of the environment. The most sustainable and eco-friendly gift is one you already have, so get creative about reusing materials already in or around your home (raid the recycling bin, find nice pieces of wood outside, wash out and reuse glass jars) to fashion them into new, thoughtful goods. Similarly, think vintage and secondhand—what items can you give a second life to by passing them along to someone who will find new meaning in them? Some of the most thoughtful gifts are small heirlooms—pieces of jewelry or a beloved ceramic dish—passed along to the next generation that will appreciate them. Green technology offers ways to reduce our carbon footprint in everyday life, and smart thermostats, solar lights, smart sprinklers, and smart plugs all make great gifts, saving people money and conserving our valuable resources. For those looking into home renovations or updating decor, try a new light fixture paired with smart blubs, or a new window treatment with smart shades. Even something as simple as a rain barrel can reduce energy use—and while the technology for that isn't very sophisticated, it certainly is, like composting, "smart." Integrated outdoor living is the ultimate gift, allowing us to bring the natural world into our homes. However, doing so sustainably takes a little more effort than simply leaving the doors to the deck open all the time. First, find eco-friendly and sustainable outdoor furniture, perhaps thrifting it or buying it used and fixing it up for a one-of-a-kind gift. If you can't go secondhand, choose furniture made of sustainable materials such as reclaimed wood, recycled plastic (great for outdoor rugs), or bamboo. For smaller gifts, consider solar lights, a water feature that recycles water, a rain barrel, or even a set of handmade wind chimes made from seashells. Story editing by Carren Jao. Additional editing by Kelly Glass. Copy editing by Paris Close. Photo selection by Clarese Moller. This story originally appeared on Made Trade and was produced and distributed in partnership with Stacker Studio. Get the latest local business news delivered FREE to your inbox weekly.

Canadian investment fund Brookfield said Wednesday it has dropped its bid for Spanish pharmaceutical firm Grifols following disagreement over its valuation. Brookfield and the Grifols family, which owns about a third of the Barcelona-based company that makes medicine derived from blood plasma, have since July been in talks to take it private. Earlier this month Brookfield made a 6.45-billion-euro bid for Grifols, offering a tentative non-binding price of 10.50 euros ($11) per share. Grifols swiftly rejected the bid, saying it "significantly underestimated the fundamental prospects and long-term potential" of the company. In a statement sent to Spanish stock market regulator CNMV, Brookfield said it was "not in a position to continue with a potential offer" for Grifols. Grifols said its board agreed that "it is not feasible that the transaction goes ahead" and remains focused on "improving the company's long-term value". Its share price plunged in January after US hedge fund Gotham City released a research note accusing the company of "manipulating" its reported debt and operational results to "artificially reduce" its debt ratio, and therefore its financing costs. Grifols has repeatedly denied the allegations. Gotham City is a prominent "short-seller" hedge fund that borrows stock in a company and sells it, hoping to buy it back cheaper to return it to the lender and pocket the difference. Grifols traces its history back to 1909, first as a blood analysis and transfusion laboratory before specialising in products derived from blood plasma. It is present in more than 30 countries including Australia, the United States and Japan. It posted revenue of 6.6 billion euros in 2023, a 10.9 percent increase over the previous year. vab/imm/cwAUSTIN, Texas (AP) — Any Texas or Texas A&M player has heard the lore of the rivalry between the two schools, a grudge match that dates to 1894. But for more than a decade — two generations of college football players — that's all it has been: Ghostly memories of great games and great plays made by heroes of the distant past. That changes this week when one of college football's great rivalries is reborn. Third-ranked Texas (10-1, 6-1) and No. 20 Texas A&M (8-3, 5-2) meet Saturday night for the first time since 2011, with a berth in the Southeastern Conference championship game on the line . “Guys that have been in my position and bleed burnt orange, they have not gotten to play this game,” said Texas fourth-year junior safety Michael Taaffe, who grew up in Austin. “Remember them when you step on Kyle Field.” For Aggies fans, who have carried the misery of Texas' 27-25 win in 2011, getting the Longhorns back in front of a frenzied crowd in College Station is a chance for some serious payback. “I was born and raised an Aggie, so I’ve been dreaming about playing in this game my whole life,” Texas A&M offensive lineman Trey Zuhn III said. Zuhn played high school football in Colorado, but his parents and grandparents attended A&M. At SEC media days back in August, Zuhn said his family would turn Texas gear upside down in stores. He keeps a picture of a longhorn in his room, hanging upside down, of course. “It should be the most amazing atmosphere that I’ve ever experienced,” Zuhn said. "I can’t wait for that, and I feel bad for Texas having to play in that." Texas players said they are ready. “That place is going to be rocking,” Texas senior cornerback Jahdae Barron said. “It's good to go on the road and play in hostile environments.” The Longhorns have overcome big and loud road crowds before. They won at Alabama in 2023. They won at Michigan and Arkansas, another old rival, this year. The Longhorns have won 10 in a row on an opponent’s home field. “When the hate is on us, we love it. We enjoy it,” Taaffe said. But some former Texas players say the current group has faced nothing like what awaits them in College Station. Playing at Texas A&M is more than just noise and a lot of “Horns down” hand signals. The “Aggie War Hymn” fight song calls for Aggies to “Saw varsity’s horns off." Beating Texas is their passion, said former Longhorns All-American offensive lineman Dan Neil, who won at Texas A&M in in 1995. He calls that win one of the best of his career. “I was done showering and getting ready to leave, and their fans were still standing outside the locker room screaming and throwing things,” he said. “The (Texas) players have no idea what they are walking into. They have no clue. No one on that team has walked into that stadium in burnt orange.” The rivalry broke up when Texas A&M left the Big 12 for the SEC in 2012. The Aggies have twice finished tied for second but have otherwise found little success there. Texas is in its first year in the SEC and has smashed its way to the top. Texas is the only SEC team with one loss this late in the season, which would make beating Texas that much sweeter for A&M. “The hype is definitely saying it's a rivalry. History says it's a rivalry, but for us, it's the football game we have this week,” Texas senior center Jake Majors said. “It's important for us to not let the environment, the game, get the best of us. ... I get to go out there and play not only for me and my team, but for the guys who came before me, so that's a true honor to have.” Even though the game hasn't been played since 2011, there has always been an element of the rivalry simmering under the surface, Texas A&M coach Mike Elko said. Elko is in his first year as the Aggies' coach, but he was the Texas A&M defensive coordinator under Jimbo Fisher from 2018-2021. “Even though it hasn’t been played, it just doesn’t feel like it’s ever really left the fabric. I really don’t think it’s as removed from the psyche as maybe it feels,” Elko said. “I think our kids are very much aware of what this is all about.” Rieken reported from College Station, Texas. Get poll alerts and updates on the AP Top 25 throughout the season. Sign up here . AP college football: https://apnews.com/hub/ap-top-25-college-football-poll and https://apnews.com/hub/college-footballA novel design concept for fuel cell electrolytesGREENVILLE, N.C. (AP) — Darryl Simmons II's 29 points helped Gardner-Webb defeat East Carolina 84-79 on Saturday night. Simmons also had five rebounds for the Runnin' Bulldogs (5-8). Anthony Selden shot 5 for 13 (3 for 6 from 3-point range) and 5 of 8 from the free-throw line to add 18 points. Isaiah Richards went 6 of 8 from the field to finish with 12 points. The victory snapped a five-game slide for the Runnin' Bulldogs. The Pirates (8-5) were led in scoring by RJ Felton, who finished with 19 points. Joran Riley added 18 points, eight rebounds, four steals and two blocks for East Carolina. Cam Hayes also recorded 18 points and four assists. Simmons scored 11 points in the first half and Gardner-Webb went into the break trailing 37-35. Simmons' 18-point second half helped Gardner-Webb finish off the five-point victory. The Associated Press created this story using technology provided by Data Skrive and data from Sportradar .

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