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ATLANTA (AP) — President Joe Biden's administration announced Tuesday that the U.S. Department of Energy will make a $6.6 billion loan to Rivian Automotive to build a factory in Georgia that had stalled as the startup electric vehicle maker struggled to become profitable. It's unclear whether the administration can complete the loan before Donald Trump becomes president again in less than two months, or whether the Trump administration might try to claw the money back. Trump previously vowed to end federal electric vehicle tax credits , which are worth up to $7,500 for new zero-emission vehicles and $4,000 for used ones. Rivian made a splash when it went public and began producing large electric R1 SUVs, pickup trucks and delivery vans at a former Mitsubishi factory in Normal, Illinois, in 2021. Months later, the California-based company announced it would build a second, larger, $5 billion plant about 40 miles (64 kilometers) east of Atlanta, near the town of Social Circle. The R1 vehicles cost $70,000 or more. The company plans to produce R2 vehicles, a smaller SUV, in Georgia with lower price tags aimed at a mass market. The first phase of Rivian’s Georgia factory is projected to make 200,000 vehicles a year, with a second phase capable of another 200,000 a year. Eventually, the plant is projected to employ 7,500 workers. But Rivian was unable to meet production and sales targets and rapidly burned through cash. In March, the company said it would pause construction of the Georgia plant. The company said it would begin assembling its R2 SUV in Illinois instead. CEO RJ Scaringe said the move would allow Rivian to start selling the R2 sooner and save $2.25 billion in capital spending. Since then, German automaker Volkswagen AG said in June it would invest $5 billion in Rivian in a joint venture in which Rivian would share software and electrical technology with Volkswagen. The money eased Rivian's cash crunch. Tuesday's announcement throws a lifeline to Rivian's grander plans. The company said its plans to make the R2 and the smaller R3 in Georgia are back on and that production will begin in 2028. “This loan would enable Rivian to more aggressively scale our U.S. manufacturing footprint for our competitively priced R2 and R3 vehicles that emphasize both capability and affordability,” Scaringe said in a statement. The Energy Department said the loan would substantially boost electric vehicles made in the United States and support Biden’s goal of having zero-emission vehicles make up half of all new U.S. sales by 2030. “As one of a few American EV startups with light duty vehicles already on the road, Rivian’s Georgia facility will allow the company to reach production volumes that make its products more cost competitive and accelerate access to international markets,” the department said in a statement. The loan includes $6 billion, plus $600 million in interest that will be rolled into the principal. The money would come from the Advanced Technology Vehicles Manufacturing Loan Program, which provides low-interest loans to make fuel-efficient vehicles and components. The program has focused mostly on loans to new battery factories for electric vehicles under Biden, but earlier helped finance initial production of the Tesla Model S and Nissan Leaf, two pioneering electric vehicles. Story continues below video The loan program, created in 2007, requires a "reasonable prospect of repayment" of the loan. Under Biden, the program has announced deals totaling $33.3 billion, including $9.2 billion for massive battery plants in Tennessee and Kentucky for Ford’s electric vehicles. Democratic U.S. Sen. Jon Ossoff , who has been a vocal supporter of electric vehicle and solar manufacturing in Georgia, hailed Tuesday's announcement as “yet another historic federal investment in Georgia electric vehicle manufacturing.” Ossoff had asked Energy Secretary Jennifer Granholm to support the loan in July. “Our federal manufacturing incentives are driving economic development across the state of Georgia,” Ossoff said in a statement. Georgia Gov. Brian Kemp says his goal is to make Georgia a center of the electric vehicle industry. But the Republican has had a strained relationship with the Biden administration over its industrial policy, even as some studies have found Georgia has netted more electric vehicle investment than any other state. Kemp has long claimed that manufacturers were picking Georgia before Biden's signature climate law, the Inflation Reduction Act, was passed. Efforts to bring Rivian to Georgia predated the Biden administration and "our shared vision to bring opportunity to Georgia will remain no matter who resides in the White House or what party controls Congress,” Kemp spokesperson Garrison Douglas said Tuesday. The loan to Rivian could rescue one of the Kemp administration's signature economic development projects even as Biden leaves office. That could put Rivian and Kemp in the position of defending the loan if Trump tries to quash it. State and local governments offered Rivian an incentive package worth an estimated $1.5 billion in 2022. Neighbors opposed to development of the Georgia site mounted legal challenges. State and local governments spent around $125 million to buy and prepare the nearly 2,000-acre (810-hectare) site. The state also has completed most of $50 million in roadwork that it pledged. The pause at Rivian contrasts with rapid construction at Hyundai Motor Group’s $7.6 billion electric vehicle and battery complex near Savannah. The Korean automaker said in October that it had begun production in Ellabell, where it plans to eventually employ 8,500. Associated Press writer Matthew Daly in Washington contributed to this story.Road problems continue for Kraken, falling 2-1 in Los AngelesTrump taps Rollins as agriculture chief, completing proposed slate of Cabinet secretariesph365 download for android latest version 。

Cancer has long been considered a disease that primarily affects older individuals. However, in recent years, there has been a concerning trend of cancer occurring in younger populations. Among the various types of cancer, stomach cancer, also known as gastric cancer, has shown a notable increase in incidence among younger individuals. This phenomenon can be attributed to a multitude of factors, showcasing the complex nature of the disease.Byfield scores in 200th career game as Kings hold off Kraken for 2-1 winThe awards ceremony, held in the vibrant city of Hangzhou, was a star-studded event attended by top athletes, coaches, officials, and fans from around the world. The anticipation was palpable as the audience eagerly awaited the announcement of the winners in each category, and when the Liang Wang Duo's names were called out, the room erupted in applause and cheers, a fitting tribute to their exceptional talent and hard work.Looking ahead, the future of overseas warehousing in Southeast Asia looks promising, with continued investments in technology, infrastructure, and logistics networks expected to drive further growth and innovation. As businesses seek to capitalize on the region's economic potential and tap into its growing consumer base, the demand for efficient and reliable overseas warehousing solutions is only set to increase.

YPSILANTI, Mich. (AP) — On a damp Wednesday night with temperatures dipping into the 30s, fans in sparsely filled stands bundled up to watch Buffalo beat Eastern Michigan 37-30 on gray turf. The lopsided game was not particularly notable, but it was played on one of the nights the Mid-American Conference has made its own: A weeknight. “A lot of the general public thinks we play all of our games on Tuesdays and Wednesdays, not just some of them in November,” MAC Commissioner Jon Steinbrecher said in a telephone interview this week. “What it has done is help take what was a pretty darned good regional conference and has given it a national brand and made it a national conference.” When the conference has played football games on ESPN or ESPN2 over the last two seasons, the linear television audience has been 10 times larger than when conference schools meet on Saturdays and get lost in the shuffle when viewers have many more choices. The most-watched MAC game over the last two years was earlier this month on a Wednesday night when Northern Illinois won at Western Michigan and there were 441,600 viewers, a total that doesn’t include streaming that isn’t captured by Nielsen company. During the same span, the linear TV audience has been no larger than 46,100 to watch two MAC teams play on Saturdays. “Having the whole nation watching on Tuesday and Wednesday night is a huge deal for the MAC,” Eastern Michigan tight end Jere Getzinger said. “Everybody wants to watch football so if you put it on TV on a Tuesday or Wednesday, people are going to watch.” ESPN has carried midweek MAC football games since the start of the century. ESPN and the conference signed a 13-year extension a decade ago that extends their relationship through at least the 2026-27 season. The conference has made the most of the opportunities, using MACtion as a tag on social media for more than a decade and it has become a catchy marketing term for the Group of Five football programs that usually operate under the radar in Michigan, Ohio, Indiana, Illinois and New York. Attendance does tend to go down with weeknight games, keeping some students out of stadiums because they have class or homework and leading to adults staying away home because they have to work the next morning. “The tradeoff is the national exposure,” Buffalo coach Pete Lembo said. “You know November nights midweek the average fan is going to park on the couch, have a bowl of chips and salsa out in front, and watch the game from there." When the Bulls beat Ball State 51-48 in an overtime thriller on a Tuesday night earlier this month, the announced attendance was 12,708 and that appeared to be generous. There were many empty seats after halftime. “You watch the games on TV, the stadiums all look like this,” Buffalo fan Jeff Wojcicki said. “They are not packed, but it’s the only game on, and you know where to find it.” Sleep and practice schedules take a hit as well, creating another wave of challenges for students to attend class and coaches to prepare without the usual rhythm of preparing all week to play on Saturday. “Last week when we played at Ohio in Athens, we had a 4-four bus ride home and got home at about 3:30 a.m.,” Eastern Michigan center Broderick Roman said. “We still had to go to class and that was tough, but it's part of what you commit to as an athlete.” That happens a lot in November when the MAC shifts its unique schedule. During the first two weeks of the month, the conference had 10 games on Tuesdays and Wednesdays exclusively. This week, there were five games on Tuesday and Wednesday while only one was left in the traditional Saturday slot with Ball State hosting Bowling Green. Next week, Toledo plays at Akron and Kent State visits Buffalo on Tuesday night before the MAC schedule wraps up with games next Friday and Saturday to determine which teams will meet in the conference title game on Dec. 7 in Detroit. In all, MAC teams will end up playing about 75% of their games on a Saturday and the rest on November weeknights. When the Eagles wrapped up practice earlier this week, two days before they played the Bulls, tight end Jere Getzinger provided some insight into the effects of the scheduling quirk. “It's Monday, but for us it's like a Thursday,” he said. Bowling Green coach Scot Loeffler said he frankly has a hard time remembering what day it is when the schedule shift hits in November. “The entire week gets turned upside down,” Loeffler said. “It’s wild, but it’s great for the league because there’s two days a week this time of year that people around the country will watch MAC games.” AP freelance writer Jonah Bronstein contributed to this report. Get poll alerts and updates on the AP Top 25 throughout the season. Sign up here . AP college football: https://apnews.com/hub/ap-top-25-college-football-poll and https://apnews.com/hub/college-footballIn this era of rapid technological advancement and shifting consumer preferences, the corn industry finds itself at a crossroads, poised for transformation. The emergence of the "lifesaving straw" represents a unique opportunity for the industry to reinvent itself, adopt new technologies, and embrace sustainability. As market sentiment undergoes a subtle but perceptible change, the future of corn hangs in the balance, waiting to see which direction it will ultimately take.It is important to acknowledge that the implementation of extraordinary countercyclical adjustment measures comes with its own set of challenges and trade-offs. Policymakers must strike a delicate balance between providing immediate support to the economy and ensuring long-term sustainability and stability. Additionally, coordination and cooperation between different policy authorities, as well as effective communication with stakeholders, are crucial for the successful implementation of these measures.

As tensions escalated, the woman insisted that the man show her his phone to verify that he had not captured any unauthorized footage. Reluctantly, the man handed over his phone for inspection, which revealed a series of recent photographs taken in the mall. The woman's suspicions were heightened as she observed that some of the photos appeared to have been taken surreptitiously, with shots of her and other unsuspecting individuals.In a world where image is everything, Xiaohua's flawless haircut for Xiang Zuo serves as a reminder of the power of a great hairstylist and the impact they can have on shaping one's appearance. The attention to detail, precision, and creativity displayed in the hair makeover showcase Xiaohua's talent and expertise, solidifying his reputation as a top hairstylist in the industry.WILMETTE, Ill., Dec. 05, 2024 (GLOBE NEWSWIRE) -- Monopar Therapeutics Inc. (Nasdaq: MNPR), a clinical-stage biotechnology company focused on developing innovative treatments for patients with unmet medical needs, today announced the first patient ever dosed with MNPR-101-Lu. This novel therapeutic radiopharmaceutical combines MNPR-101, Monopar’s antibody that selectively targets the urokinase plasminogen activator receptor (uPAR), with the therapeutic radioisotope lutetium-177. uPAR is involved in tumor growth and metastasis, and is found in some of the most aggressive, deadly cancers, including pancreatic, ovarian, triple negative breast, and colorectal cancers. The MNPR-101-Lu intravenous infusion was well-tolerated with no serious adverse reactions reported. This patient, dosed under a compassionate use protocol in the US, has metastatic pancreatic cancer, and prior to dosing, the cancer was imaged using MNPR-101-Zr (a zirconium-89 imaging radioisotope conjugated to MNPR-101) with a PET/CT scanner and showed uPAR expression. “As a result of encouraging biodistribution and dosimetry clinical data we recently reported ( link ) with our radiodiagnostic, MNPR-101-Zr, we have been eagerly looking forward to initiating treatment of patients with MNPR-101-Lu, hopeful it may provide an important therapeutic benefit to a group of cancer patients very much in need,” said Chandler Robinson, MD, Monopar’s Chief Executive Officer. “We are thrilled to have dosed this patient with MNPR-101-Lu, and believe this may be the world’s first dosing of a patient with a uPAR-targeted therapeutic radiopharmaceutical,” said Andrew Cittadine, Monopar’s Chief Operating Officer. Monopar is actively enrolling participants in two Phase 1 clinical studies in Australia, evaluating MNPR-101-Zr for imaging and MNPR-101-Lu for treatment of advanced solid tumors. Further information about the MNPR-101-Lu Phase 1a trial is available at www.ClinicalTrials.gov under study identifier NCT06617169 . Further information about the MNPR-101-Zr Phase 1 imaging and dosimetry clinical trial is available at www.ClinicalTrials.gov under study identifier NCT06337084 . About Monopar Therapeutics Inc. Monopar Therapeutics is a clinical-stage biotechnology company with ALXN-1840 for Wilson disease which has completed a Phase 3 trial, and radiopharma programs including Phase 1-stage MNPR-101-Zr for imaging advanced cancers, and Phase 1a-stage MNPR-101-Lu and late preclinical-stage MNPR-101-Ac225 for the treatment of advanced cancers. For more information, visit: www.monopartx.com . Forward-Looking Statements Statements contained in this press release regarding matters that are not historical facts are "forward-looking statements" within the meaning of the Private Securities Litigation Reform Act of 1995. The words “may,” “will,” “could,” “would,” “should,” “expect,” “plan,” “anticipate,” “intend,” “believe,” “estimate,” “predict,” “project,” “potential,” “continue,” “target” and similar expressions are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words. Examples of these forward-looking statements include statements concerning: the MNPR-101-Lu intravenous infusion was well-tolerated with no serious adverse reactions reported; that as a result of recently reported encouraging biodistribution and dosimetry clinical data with Monopar’s radiodiagnostic, MNPR-101-Zr, the Company has been eagerly looking forward to initiating treatment and to seeing if the Company can bring an important therapeutic benefit to a group of cancer patients very much in need; and the Company believes this may be the world’s first dosing of a patient with a uPAR-targeted therapeutic radiopharmaceutical. The forward-looking statements involve risks and uncertainties including, but not limited to: that the patient may develop a serious adverse event in the future to MNPR-101-Lu; that radiation dosimetry analytics in the future may not be consistent with the estimated data generated thus far; that Monopar may not find enough patients to successfully enroll its MNPR-101-Lu therapeutic study; that the Phase 1 imaging and dosimetry clinical trial in advanced cancer patients with MNPR-101-Zr may not yield consistently satisfactory results; that future preclinical or clinical data may not be as promising as the data to date; that MNPR-101-Zr and/or MNPR-101-Lu may cause unexpected serious adverse effects or fail to be effective against the cancer tumors in humans; that the trials could result in a clinical hold should there be a Serious Adverse Event; Monopar’s ability to raise sufficient funds in order for the Company to support continued clinical, regulatory and commercial development of its programs and to make contractual future milestone payments, as well as its ability to further raise additional funds in the future to support any future product candidate programs through completion of clinical trials, the approval processes and, if applicable, commercialization; uncertainties related to the regulatory discussions that Monopar intends to initiate related to ALXN-1840 and the outcome thereof; the rate of market acceptance and competitiveness in terms of pricing, efficacy and safety, of any products for which Monopar receives marketing approval, and Monopar’s ability to competitively market any such products as compared to larger pharmaceutical firms; and the significant general risks and uncertainties surrounding the research, development, regulatory approval, and commercialization of imaging agents and therapeutics. Actual results may differ materially from those expressed or implied by such forward-looking statements. Risks are described more fully in Monopar's filings with the Securities and Exchange Commission. All forward-looking statements contained in this press release speak only as of the date on which they were made. Monopar undertakes no obligation to update such statements to reflect events that occur or circumstances that exist after the date on which they were made. Any forward-looking statements contained in this press release represent Monopar’s views only as of the date hereof and should not be relied upon as representing its views as of any subsequent date. CONTACT: Monopar Therapeutics Inc. Investor Relations Karthik Radhakrishnan Chief Financial Officer karthik@monopartx.com Follow Monopar on social media for updates: Twitter: @MonoparTx LinkedIn: Monopar TherapeuticsMeanwhile, in a separate development, Chinese tech tycoon Lei Jun made headlines with the announcement of the upcoming release of his new electric vehicle, YU. Lei Jun, the founder and CEO of Xiaomi Corporation, unveiled his ambitious plans to venture into the electric vehicle market and introduce a cutting-edge automobile under the YU brand.

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Atletico thrash Valladolid 5-0 to provisionally move to second in LaLigaLei Jun's announcement of the new car YU generated considerable excitement and speculation within the tech and automotive communities, as industry experts and consumers eagerly anticipate the unveiling of this highly anticipated electric vehicle. With Lei Jun's track record of success and Xiaomi's reputation for innovation, YU is poised to make a significant impact in the electric vehicle market and redefine the concept of smart mobility.

'That draw feels like a win' - City fans react to Baggies tieFollowing yet another impressive victory, Chelsea players took the opportunity to express their gratitude to the loyal supporters who have stood by them through thick and thin. The post-match scenes were nothing short of jubilant, as players applauded the fans, signed autographs, and took selfies with young admirers. The bond between the team and its supporters was palpable, a testament to the mutual respect and admiration that exists between the two.MINNEAPOLIS — In its ninth try, Fertile-Beltrami football finally has a state championship. The Falcons took command in the second half and defeated Hills-Beaver Creek 20-8 in the Minnesota 9-man Prep Bowl championship game on Saturday at U.S. Bank Stadium. Jonah Harstad and Isaiah Wright ran for third quarter touchdowns and, after Hills-Beaver Creek trimmed to lead to 14-8 late in the third, Harstad ran for the game's final score with about four minutes to play. The Falcons finished the season 13-0 and gave 30-year head coach Brian Nelson the biggest of his 207 career victories. Neither team could muster much offensively in a scoreless first half. Of the Falcons' five possessions, three ended on failed fourth down tries, another on a fumble and they punted on their first drive. Hills-Beaver Creek lost the ball on downs to open the game, punted and then had two drives end on F-B interceptions. But F-B got rolling after stopping the Patriots on downs on the first possession of the second half. The Falcons drove 47 yards in eight plays, with Harstad scoring from 2-yards out for a 6-0 lead with 5:05 left in the third quarter. F-B's Preston Hanson recovered a Patriots fumble on the ensuing drive and the Falcons drove 42 yards in six plays, with Wright scoring on a 3-yard run and adding the 2-point run for a 14-0 lead with 2:31 left in the third. H-BC got back in it when quarterback Jamin Metzger connected with James VandenBosch on a 53-yard TD pass with 2:09 left in the third quarter to make it 14-8 Falcons. But the Falcons answered on their next possession, with Harstad running it in from 1-yard out to cap an eight-play, 50-yard drive to make it 20-6 with 10 minutes to play. F-B turned H-BC over on downs on its next possession but the Patriots got another shot when Harstad lost a fumble at the Patriots' 16 yard line with 3:23 left in the game. However, Wright intercepted a Metzger pass four plays later and returned it 17 yards to the H-BC 33 yard line with 2:31 to play. On second down, Wright ran 10 yards for a first down to the Patriots 20 yard line with two minutes left and the Falcons burned the remaining time to end the game. Wright carried 33 times for 185 yards and a TD and Harstad ran for 28 yards and two scores on 14 carries. Quarterback Easton Petry hit 7 of 10 passes for 91 yards. Bryer Strem made four catches for 41 yards, and he also intercepted two passes in the first half. Caleb Sather led the Falcons with nine total tackles, Hanson made eight solo stops, and Jack Leiser had six tackles. All three had tackles for lost yards. H-BC's Metzger hit 11 of 18 passes for 114 yards but was intercepted three times. He led Patriots rushers with 30 yards on seven carries. VandenBosch had four receptions for 81 yards and a touchdown.

As a football fan who appreciates the beauty of attacking football, it is disheartening to see a storied club like Arsenal struggle to produce goals from open play. While set pieces can certainly be a valuable weapon in a team's arsenal, they should not be the primary source of goals for a top-tier club with ambitions of competing for trophies at the highest level.VinFast Powers Ahead: Q3 Sales Surge 49%, Vehicle Deliveries Double & More