number king jili

NEW YORK, Dec. 07, 2024 (GLOBE NEWSWIRE) -- Y-mAbs Therapeutics, Inc. (the “Company” or “Y-mAbs”) (Nasdaq: YMAB), a commercial-stage biopharmaceutical company focused on the development and commercialization of novel radioimmunotherapy and antibody-based therapeutic products for the treatment of cancer, today announced the presentation of CD38-SADA in Non-Hodgkin Lymphoma (NHL) preclinical data and trial in progress posters at the 66 th American Society of Hematology (ASH) Annual Meeting & Exposition being held on December 7 –10, 2024, in San Diego, California. A poster titled “ CD38-SADA, a S elf- A ssembling and D is- A ssembling Bispecific Fusion Protein for Two-Step Pretargeted Radioimmunotherapy of Non-Hodgkin Lymphoma ” characterizes the selective binding of CD38-SADA to DOTA-chelated lanthanide metals and high-avidity binding to CD38, a tumor specific antigen overexpressed across a range of lymphoma cells. Data from this poster demonstrate anti-tumor efficacy of CD38-SADA when used with Lutetium 177 (Lu 177 )-DOTA in a two-step approach to pre-targeted radioimmunotherapy (“PRIT”). Tumor responses in a xenograft mouse model were rapid and dose-dependent, further supporting the clinical development of CD38-SADA PRIT in patients with CD38-positive lymphoid malignancies. “This preclinical analysis provides important insights into the unique pharmacology of CD38-SADA and its therapeutic potential for NHL,” said Brian H. Santich, Ph.D., the lead author and co-inventor of the SADA PRIT technology platform. “The anti-tumor efficacy positively correlated with increasing doses of Lu 177 -DOTA and CD38-SADA, which informed the study design and initial dosing regimen of our Trial 1201 in patients with NHL.” In addition, Y-mAbs presents a trial-in-progress poster from its ongoing Phase 1 (Trial 1201) clinical study evaluating the safety and tolerability of CD38-SADA PRIT with Lu 177 -DOTA in adults with relapsed or refractory NHL. Trial 1201 is a first-in-human, dose-escalation, open-label, multicenter study composed of two parts. Part A includes dose escalation of the CD38-SADA bispecific fusion protein to define the optimal safe dose of the CD38-SADA protein, the administration interval between CD38-SADA and Lu 177 -DOTA, and the Lu 177 -DOTA dose for tumor imaging. In Part B, dose escalation of Lu 177 -DOTA will establish the optimal therapeutic dose of the radioactive payload. For each part, the escalation is based on a 3+3 trial design of 4 planned dose levels. “We are pleased to share the details of this Phase 1 clinical trial, which is investigating a potentially transformative approach to pre-targeted radioimmunotherapy for patients with relapsed and refractory NHL,” said Vignesh Rajah, MBBS, DCH, MRCP (UK), Chief Medical Officer. “This is our second clinical program evaluating the SADA PRIT technology platform and our first in hematological malignancies.” The abstract details are below: Abstract Title: “ CD38-SADA, a Self-Assembling and Dis-Assembling Bispecific Fusion Protein for Two-Step Pretargeted Radioimmunotherapy of Non-Hodgkin Lymphoma” Format : Poster Presentation, ID: 1599 Date and Time: Saturday, December 7, 2024, 5:30 PM-7:30 PM Abstract Title: “ CD38-SADA Pretargeted Radioimmunotherapy (PRIT) with Lutetium 177 (Lu177)-DOTA in Adult Patients with Relapsed or Refractory Non-Hodgkin Lymphoma: A First-in-Human Phase 1 Trial” Format : Poster Presentation, ID: 4434.1 Date and Time: Monday, December 9, 2024, 6:00 PM-8:00 PM Researchers at Memorial Sloan Kettering Cancer Center (MSK), including Dr. Nai-Kong Cheung, developed the SADA technology for radioimmunotherapy, which is exclusively licensed by MSK to Y-mAbs. Dr. Cheung has intellectual property rights and interests in the technology, and as a result of this licensing arrangement, MSK has institutional financial interests in the technology. About Y-mAbs Y-mAbs is a commercial-stage biopharmaceutical company focused on the development and commercialization of novel, radioimmunotherapy and antibody-based therapeutic cancer products. The Company’s technologies include its investigational Self-Assembly DisAssembly (“SADA”) Pretargeted Radioimmunotherapy Platform (“PRIT”) and bispecific antibodies generated using the Y-BiClone platform. The Company’s broad and advanced product pipeline includes the anti-GD2 therapy DANYELZA® (naxitamab-gqgk), the first FDA-approved treatment for patients with relapsed or refractory high-risk neuroblastoma in the bone or bone marrow after a partial response, minor response, or stable disease to prior therapy. About CD38-SADA PRIT CD38-SADA is a bispecific fusion protein that tightly binds to the CD38 antigen and to select radionuclides chelated to tetraxetan (or “DOTA”). CD38-SADA contains a p53-derived domain that drives the self-assembly of CD38-SADA tetramers, which possess four distinct binding sites for CD38. In the first step of pre-targeted radiotherapy, non-radiolabeled-CD38-SADA tetramers are infused and bind with high avidity to CD38-positive tumors, while unbound CD38-SADA disassembles into low molecular weight monomers that are removed by the kidney. The second infusion delivers the “radioactive payload,” which binds to the CD38-SADA on tumor cells for localized irradiation. CD38-SADA PRIT with Lutetium 177 (Lu 177)-DOTA is now under clinical investigation in Trial 1201 (NCT05994157). Forward-Looking Statements Statements in this press release about future expectations, plans and prospects, as well as any other statements regarding matters that are not historical facts, may constitute “forward-looking statements” within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934. Such statements include, but are not limited to, statements about our business model, including financial outlook for 2024 and beyond, including estimated operating expenses, use of cash and cash equivalents and DANYELZA product revenue and sufficiency of cash resources and related assumptions; expectations with respect to the Company’s future financial performance; implied and express statements regarding the future of the Company’s business, including with respect to expansion and its goals; expectations with respect to the Company’s plans and strategies, development, regulatory, commercialization and product distribution plans, including the timing thereof; expectations with respect to the Company’s products and product candidates, including potential territory and label expansion of DANYELZA and the potential market opportunity related thereto and potential benefits thereof, and the potential of the SADA PRIT technology and potential benefits and applications thereof; expectations relating to key anticipated development milestones, including potential expansion and advancement of commercialization and development efforts, including potential indications, applications and geographies, and the timing thereof; expectations with respect to current and future clinical and pre-clinical studies and the Company’s research and development programs, including with respect to timing and results; expectations regarding collaborations or strategic partnerships and the potential benefits thereof; and other statements that are not historical facts. Words such as ‘‘anticipate,’’ ‘‘believe,’’ “contemplate,” ‘‘continue,’’ ‘‘could,’’ ‘‘estimate,’’ ‘‘expect,’’ “hope,” ‘‘intend,’’ ‘‘may,’’ ‘‘might,’’ ‘‘plan,’’ ‘‘potential,’’ ‘‘predict,’’ ‘‘project,’’ ‘‘should,’’ ‘‘target,’’ “will,” ‘‘would’,’ “guidance,” “goal,” “objective,” and similar expressions are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words. Our product candidates and related technologies are novel approaches to cancer treatment that present significant challenges. Actual results may differ materially from those indicated by such forward-looking statements as a result of various factors, including but not limited to: risks associated with the Company’s financial condition and need for additional capital; the risks that actual results of the Company’s restructuring plan and revised business plan will not be as expected; risks associated with the Company’s development work; cost and success of the Company’s product development activities and clinical trials; the risks of delay in the timing of the Company’s or its partners’ regulatory submissions or failure to receive approval of its drug candidates; the risks related to commercializing any approved pharmaceutical product including the rate and degree of market acceptance of product candidates; development of sales and marketing capabilities and risks associated with failure to obtain sufficient reimbursement for products; risks related to the Company’s dependence on third parties including for conduct of clinical testing and product manufacture as well as regulatory submissions; the Company’s ability to enter into new partnerships or to recognize the anticipated benefits from its existing partnerships; risks related to government regulation; risks related to market approval, risks associated with protection of the Company’s intellectual property rights; risks related to employee matters and managing growth; risks related to the Company’s common stock, risks associated with macroeconomic conditions, including the conflict between Russia and Ukraine and sanctions related thereto, the state of war between Israel and Hamas and the related risk of a larger regional conflict, inflation, increased interest rates, uncertain global credit and capital markets and disruptions in banking systems; and other risks and uncertainties affecting the Company including those described in the “Risk Factors” section included in the Company’s Annual Report on Form 10-K for the fiscal year ended December 31, 2023, and the Company’s Quarterly Report on Form 10-Q for the quarterly periods ended March 31, 2024, and September 30, 2024, and future filings and reports by the Company. Any forward-looking statements contained in this press release speak only as of the date hereof, and the Company undertakes no obligation to update any forward-looking statement, whether as a result of new information, future events or otherwise. SADA®, SADA PRIT®, DANYELZA® and Y-mAbs® are registered trademarks of Y-mAbs Therapeutics, Inc. Investor Contact: Courtney Dugan VP, Head of Investor Relations cdu@ymabs.comnumber king jili 。

From Bitcoin and Ozempic to Taylor Swift, seven charts reveal why 2024 broke recordsJapan's famous sake joins UNESCO's cultural heritage list, a boost to brewers and enthusiasts

Farage: Badenoch must apologise for ‘crazy conspiracy theory’ on Reform numbersThe crypto space is teeming with presale events, yet the current rivalry between Crypto All-Stars (STARS) and BlockDAG (BDAG) is exceptionally fierce. Crypto All-Stars has captured widespread interest with its meme coin charm, while BlockDAG has made impressive strides, rapidly growing in the presale market. BlockDAG (BDAG) has accumulated over $158 million in less than a year. Its presale achievements are unmatched, making it the focal point in the community. But does this make it the superior option? We’ll compare their numbers, technology, and community support to see. The Reality Behind Crypto All-Stars Promises Crypto All-Stars has gathered over $6.2 million in its presale, thanks to its unique MemeVault staking platform, catering to various meme tokens. This platform offers a high annual yield of up to 316% in staking rewards, appealing to those seeking profitable meme coin ventures. However, Crypto All-Stars lacks a detailed future plan, leaving doubts about its viability post-presale. The absence of a clear roadmap raises concerns about the project’s longevity and transparency, which could be risky after the presale excitement wanes. The Unmatched Growth of BlockDAG’s Presale BlockDAG’s presale has dramatically reshaped expectations, raising over $158 million in less than a year and progressing to batch 26, with 16.9 billion BDAG coins sold. The current price per coin is $0.0234, presenting an extraordinary 2,240% ROI to early supporters. This significant return and strong presale momentum are fueling excitement daily. BlockDAG stands out with its pioneering Directed Acyclic Graph (DAG) technology, which enhances transaction speeds, scalability, and security beyond traditional blockchain technology. BlockDAG is also undergoing a Mainnet audit, a vital step toward its operational launch. Continuously reaching new milestones, BlockDAG is on track to potentially hit $600 million. The enthusiasm is tangible, and the prospects for BlockDAG look promising as it gears up for its next significant development phase. Uncertainty in Crypto All-Stars Future Gives BlockDAG the Edge Crypto All-Stars presale, despite its initial success and the launch of its staking platform, lacks a clear vision for the future. This vagueness about its long-term objectives makes it difficult for enthusiasts to gauge the project's direction. In sharp contrast, BlockDAG has consistently achieved its set goals, from its initial launch to the Testnet in September, and even through the detailed auditing of its Mainnet. BlockDAG’s methodical planning and steady progress have secured its reputation within the crypto community, proving its readiness for sustained success, while Crypto All-Stars still needs to demonstrate its capability to fulfill its early promises. The Issue of Openness Transparency issues plague Crypto All-Stars, with increasing chatter on platforms like Reddit and social media about the anonymity of its team and overall secrecy. Reports of users being removed from the Telegram group for inquiring about the project's leaders exacerbate these concerns. Meanwhile, BlockDAG champions transparency with its community-driven approach. It has recently updated its website for a better user experience and introduced a structured, 5-step bonus system to maintain user engagement. Regular AMA sessions with its top leaders and straightforward updates underscore BlockDAG’s commitment to openness, setting it apart in a sector often criticized for its lack of transparency. Deciding the Better Pick While Crypto All-Stars has made its mark in the meme coin arena, its opaque operations and indefinite strategic plans have sparked notable worries. Conversely, BlockDAG has not only shown rapid growth by raising over $158 million in under a year but also boasts a clear, community-oriented strategy. BlockDAG’s cutting-edge DAG technology promotes scalability and speed, critical for enduring success. As a dominant force in the crypto presale coin market, BlockDAG is well-positioned to deliver substantial outcomes. For those looking for a reliable, transparent, and user-focused project, BlockDAG emerges as the clear superior choice. Presale: https://purchase.blockdag.network Website: https://blockdag.network Telegram: https://t.me/blockDAGnetworkOfficial Discord: https://discord.gg/Q7BxghMVyu Join our WhatsApp Channel to get the latest news, exclusives and videos on WhatsApp _____________ Disclaimer: Analytics Insight does not provide financial advice or guidance. Also note that the cryptocurrencies mentioned/listed on the website could potentially be scams, i.e. designed to induce you to invest financial resources that may be lost forever and not be recoverable once investments are made. You are responsible for conducting your own research (DYOR) before making any investments. Read more here.The hunt for UnitedHealthcare CEO's elusive killer yields new evidence, but few answers

Japan's famous sake joins UNESCO's cultural heritage list, a boost to brewers and enthusiastsMy home is a Christmas paradise with Poundland and B&M buys but trolls think it’s ‘tacky’ & feel sorry for my neighbours

Allar puts critics on mute, keeps winning for Penn StateStock market today: Wall Street gains ground as it notches a winning week and another Dow recordNvidia’s upcoming graphics cards have been exposed, just as we edge closer to CES 2025. Key details about Nvidia’s much-anticipated GPU lineup have surfaced, revealing exciting yet daunting specifications for tech enthusiasts. Thanks to a slip by graphics card producer Zotac, the names and specifications of some of Nvidia’s top GPUs have been revealed. The series, codenamed Blackwell, includes the formidable RTX 5090, which is expected to occupy significant space and demand considerable electric power once inside your PC. Insights were gathered from Zotac’s inadvertent leak, initially captured by VideoCardz before the listings were removed. The top-of-the-line RTX 5090 boasts 32GB of GDDR7 memory, an upgrade over the RTX 4090’s 24GB. Consumers can expect this giant to take up to four slots on motherboards, which marks a step up from the triple-slot requirement of its predecessor. Concerning power consumption, Nvidia suggests a power supply unit ranging from 650W to 750W, possibly pointing to a 600W total power draw. The leaked information hints at five specific cards: the GeForce RTX 5090, RTX 5090D, RTX 5080, RTX 5070 Ti, and RTX 5070. However, there’s no mention yet of more budget-friendly models like the 5060 series. This focus on high-end GPUs may delay the release and announcement of Nvidia’s lower-tier cards, traditionally launched at a later date. For budget-conscious gamers, Intel’s recent entry into the market with their more affordable offerings, such as the B580, might prove a welcome alternative. However, suspense remains for what Nvidia’s 50-series will eventually offer to those pursuing more economical gaming solutions. Get Ready for Nvidia’s Game-Changing GPU Lineup: What to Expect from the Upcoming Blackwell Series As the tech world eagerly anticipates CES 2025, Nvidia’s latest advancements in graphics processing units (GPUs) have recently been thrust into the spotlight. Thanks to a leak by Zotac, we now have a glimpse into the formidable specifications of Nvidia’s forthcoming Blackwell series. This new lineup is poised to redefine the capabilities of PC gaming and content creation. Nvidia Blackwell Series: Key Specifications Unveiled The Blackwell series is headlined by the GeForce RTX 5090, a powerhouse boasting 32GB of GDDR7 memory, outstripping the RTX 4090’s 24GB. This leap in memory capacity is expected to deliver unprecedented performance for gaming and AI applications. However, this increase in power comes with a caveat: the RTX 5090 could occupy up to four slots on motherboards, compared to the triple-slot configuration required by its predecessor. Power Requirements and Efficiency Nvidia’s recommendation of a 650W to 750W power supply hints at demanding power needs, potentially around a 600W total draw. Enthusiasts will need to ensure their systems have the appropriate power infrastructure to handle these new graphics cards, with efficient cooling systems to manage the expected heat output. The Lineup: What’s to Come In addition to the RTX 5090, the leaked details reveal upcoming models like the RTX 5090D, RTX 5080, RTX 5070 Ti, and RTX 5070. This focused reveal on high-end models suggests that Nvidia’s strategy may initially cater to enthusiasts and professionals, while budget-friendly solutions may follow later. Challenges and Competition The lack of an immediate mention of budget options like the 5060 series might leave some gamers turning to alternatives. Notably, Intel has been making waves in the budget GPU market with offerings like the B580, which provide more cost-effective solutions for gamers. Looking Forward As Nvidia prepares for its official announcements at CES 2025, tech enthusiasts and gamers alike are keenly watching to see how these cutting-edge GPUs will transform gaming and AI-driven creativity. Nvidia’s emphasis on high-performance products may set new standards for what users expect from their computing hardware. For further developments and details, keep an eye on Nvidia’s official announcements and explore more about their products by visiting their official website . Stay tuned to discover how the Blackwell series will shift the landscape of graphics technology and influence future gaming experiences.

"Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur. Excepteur sint occaecat cupidatat non proident, sunt in culpa qui officia deserunt mollit anim id est laborum." Section 1.10.32 of "de Finibus Bonorum et Malorum", written by Cicero in 45 BC "Sed ut perspiciatis unde omnis iste natus error sit voluptatem accusantium doloremque laudantium, totam rem aperiam, eaque ipsa quae ab illo inventore veritatis et quasi architecto beatae vitae dicta sunt explicabo. Nemo enim ipsam voluptatem quia voluptas sit aspernatur aut odit aut fugit, sed quia consequuntur magni dolores eos qui ratione voluptatem sequi nesciunt. Neque porro quisquam est, qui dolorem ipsum quia dolor sit amet, consectetur, adipisci velit, sed quia non numquam eius modi tempora incidunt ut labore et dolore magnam aliquam quaerat voluptatem. Ut enim ad minima veniam, quis nostrum exercitationem ullam corporis suscipit laboriosam, nisi ut aliquid ex ea commodi consequatur? Quis autem vel eum iure reprehenderit qui in ea voluptate velit esse quam nihil molestiae consequatur, vel illum qui dolorem eum fugiat quo voluptas nulla pariatur?" 1914 translation by H. Rackham "But I must explain to you how all this mistaken idea of denouncing pleasure and praising pain was born and I will give you a complete account of the system, and expound the actual teachings of the great explorer of the truth, the master-builder of human happiness. No one rejects, dislikes, or avoids pleasure itself, because it is pleasure, but because those who do not know how to pursue pleasure rationally encounter consequences that are extremely painful. Nor again is there anyone who loves or pursues or desires to obtain pain of itself, because it is pain, but because occasionally circumstances occur in which toil and pain can procure him some great pleasure. To take a trivial example, which of us ever undertakes laborious physical exercise, except to obtain some advantage from it? But who has any right to find fault with a man who chooses to enjoy a pleasure that has no annoying consequences, or one who avoids a pain that produces no resultant pleasure?" 1914 translation by H. Rackham "But I must explain to you how all this mistaken idea of denouncing pleasure and praising pain was born and I will give you a complete account of the system, and expound the actual teachings of the great explorer of the truth, the master-builder of human happiness. No one rejects, dislikes, or avoids pleasure itself, because it is pleasure, but because those who do not know how to pursue pleasure rationally encounter consequences that are extremely painful. Nor again is there anyone who loves or pursues or desires to obtain pain of itself, because it is pain, but because occasionally circumstances occur in which toil and pain can procure him some great pleasure. To take a trivial example, which of us ever undertakes laborious physical exercise, except to obtain some advantage from it? But who has any right to find fault with a man who chooses to enjoy a pleasure that has no annoying consequences, or one who avoids a pain that produces no resultant pleasure?" To keep reading, please log in to your account, create a free account, or simply fill out the form below.AI to generate $23 trillion annually: could it benefit iDEGEN?

"Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur. Excepteur sint occaecat cupidatat non proident, sunt in culpa qui officia deserunt mollit anim id est laborum." Section 1.10.32 of "de Finibus Bonorum et Malorum", written by Cicero in 45 BC "Sed ut perspiciatis unde omnis iste natus error sit voluptatem accusantium doloremque laudantium, totam rem aperiam, eaque ipsa quae ab illo inventore veritatis et quasi architecto beatae vitae dicta sunt explicabo. Nemo enim ipsam voluptatem quia voluptas sit aspernatur aut odit aut fugit, sed quia consequuntur magni dolores eos qui ratione voluptatem sequi nesciunt. Neque porro quisquam est, qui dolorem ipsum quia dolor sit amet, consectetur, adipisci velit, sed quia non numquam eius modi tempora incidunt ut labore et dolore magnam aliquam quaerat voluptatem. Ut enim ad minima veniam, quis nostrum exercitationem ullam corporis suscipit laboriosam, nisi ut aliquid ex ea commodi consequatur? Quis autem vel eum iure reprehenderit qui in ea voluptate velit esse quam nihil molestiae consequatur, vel illum qui dolorem eum fugiat quo voluptas nulla pariatur?" 1914 translation by H. Rackham "But I must explain to you how all this mistaken idea of denouncing pleasure and praising pain was born and I will give you a complete account of the system, and expound the actual teachings of the great explorer of the truth, the master-builder of human happiness. No one rejects, dislikes, or avoids pleasure itself, because it is pleasure, but because those who do not know how to pursue pleasure rationally encounter consequences that are extremely painful. Nor again is there anyone who loves or pursues or desires to obtain pain of itself, because it is pain, but because occasionally circumstances occur in which toil and pain can procure him some great pleasure. To take a trivial example, which of us ever undertakes laborious physical exercise, except to obtain some advantage from it? But who has any right to find fault with a man who chooses to enjoy a pleasure that has no annoying consequences, or one who avoids a pain that produces no resultant pleasure?" 1914 translation by H. Rackham "But I must explain to you how all this mistaken idea of denouncing pleasure and praising pain was born and I will give you a complete account of the system, and expound the actual teachings of the great explorer of the truth, the master-builder of human happiness. No one rejects, dislikes, or avoids pleasure itself, because it is pleasure, but because those who do not know how to pursue pleasure rationally encounter consequences that are extremely painful. Nor again is there anyone who loves or pursues or desires to obtain pain of itself, because it is pain, but because occasionally circumstances occur in which toil and pain can procure him some great pleasure. To take a trivial example, which of us ever undertakes laborious physical exercise, except to obtain some advantage from it? But who has any right to find fault with a man who chooses to enjoy a pleasure that has no annoying consequences, or one who avoids a pain that produces no resultant pleasure?" To keep reading, please log in to your account, create a free account, or simply fill out the form below.PALO ALTO, Calif. , Dec. 16, 2024 /PRNewswire/ -- Abstract Security announced today that it has partnered with Analytica42 to help organizations easily integrate their data sources with Google SecOps platform for analytics and storage. With the new integration, Abstract Security makes it easier for customers to migrate to Google SecOps through its pipeline management features which eases the burden of data management and routes quality data to the platform. "Analytica42 has built a reputation for delivering exceptional SIEM expertise and data migration services. Partnering with Abstract Security and their advanced pipeline technology is a natural fit. Together, we combine our services with their technology to accelerate and enhance data management and migration solutions for our clients," said Gabriel Martinez , Founder and CEO of Analytica42. Abstract provides over 100 integrations for data sources with industry-leading vendors out of the box, in addition to threat intel feeds and its own in-house ASTRO threat feed. This comprehensive ecosystem enables customers to blend their unique security data with valuable threat intelligence and insights, significantly enhancing their overall security posture and enabling more informed decision-making. Further, Abstract offers customers a fully hosted solution on Google Cloud Platform or the flexibility to deploy into their own cloud environments, giving them complete control over their cybersecurity infrastructure. "The threat landscape is only becoming more challenging, making security data operations increasingly complex, and we are so pleased to offer this partnership with Analytica42 and our integration with Google SecOps since so many of our joint customers utilize Google," said Colby DeRodeff , CEO and co-founder, Abstract Security. "From our inception, our goal has been to offer customers simplified data operations for security and this partnership with Analytica42 focusing on integration and migration is an important step in that direction for us." Abstract's security operations platform delivers analytics that quickly correlate data and delivers actionable insights at the business level, ensuring security teams can focus on what matters most. With Abstract's data pipeline management tool, customers benefit from Abstract's ability to decouple the data sources from data destinations and normalize the data in real time before it reaches a destination. Through this tool, Abstract removes dependency and makes data easily routable to any destination which saves time and money for data storage. Abstract has chosen to work with Analytica42 as a global delivery partner to ensure that the transition to a new environment is seamless with as little disruption as possible. Analytica42 offers many years of experience in the integration and migration of security tools to and from a wide range of SIEMs. This enables customers to unlock their SIEMs full potential, ensuring faster detection, quicker response times & more streamlined workflows. Rather than just simply adopting a one-size-fits-all approach, Analytica42 takes the time to understand the specific requirements, utilizing a comprehensive, pre-built library of use-cases alongside more bespoke solutions to minimize false positives & ensure you have full visibility across your security landscape. About Analytica42 Analytica42, founded by IT and security experts with over two decades of experience, specializes in SIEM/SOAR/CTI enablement, migration, transformation, and co-management. Our expertise spans blue and red team operations, threat research, and advanced development. With a combined 80+ years of experience, our team delivers innovative, customer-focused solutions that enhance security operations and drive long-term success. Through our Velocity approach, we provide tailored solutions for rapid threat detection, mitigation, and response, helping organizations maximize their SIEM and SOAR investments. Analytica42 builds secure foundations for today while ensuring resilience for tomorrow, turning security challenges into opportunities for growth. For more information about the company, please visit www.analytica42.com or follow us on Linkedin . About Abstract Security Abstract Security, founded in 2023, has built a revolutionary platform equipped with an AIpowered assistant to better centralize the management of security analytics. Crafted by category creators and industry veterans known for redefining the cybersecurity landscape, Abstract transcends next-gen SIEM solutions by correlating data in real time between data streams. As a result, compliance and security data can be leveraged separately to increase detection effectiveness and lower costs – an approach that does not currently exist in the market. The leadership team of Colby DeRodeff , Ryan Clough , Aaron Shelmire , Chris Camacho , and Stefan Zier bring a unique set of experiences and backgrounds in product development and company-building expertise, at companies such as ArcSight (acq. by HP), Mandiant (acq. by Google), Palo Alto Networks and Sumo Logic. For more information about the company, please visit https://www.abstract.security/ and follow the journey on LinkedIn and Youtube ! Contact Rich Mullikin 925-354-7444 rich@mullikincommunications.com View original content to download multimedia: https://www.prnewswire.com/news-releases/abstract-security-joins-forces-with-analytica42-to-supercharge-integration-delivery-including-integration-to-google-secops-platform-302332908.html SOURCE Abstract Security Inc

In a recent appearance at the New York Times DealBook Summit, Jeff Bezos , executive chair of Amazon Inc. , revealed his simple yet effective strategy for the company’s ongoing success . What Happened : Bezos stressed the significance of concentrating on “a few things” to ensure the $2.32 trillion company remains on the right path. These crucial factors include pinpointing big ideas, implementing rigorous execution against these ideas, and fostering the next generation of leaders. Bezos said there are three elements that can help anyone get ahead. "Big leaders have to identify big ideas. They have to enforce tough execution against those big ideas and they need to grow the next generation of leaders," he said at the summit and as quoted by CNBC. Bezos, who relinquished his role as Amazon’s CEO in 2021, is currently aiding CEO Andy Jassy and the leadership team in preserving their success. Also Read: Costco Founder’s Chat With Bezos Over Coffee Helped Save Amazon Their main concentration is on artificial intelligence (AI), including Nova, Amazon’s generative AI model that was launched on Tuesday. Bezos highlighted the vast potential of AI, stating, “We’re literally working on a thousand [AI] applications internally,” suggesting that AI has the capacity to enhance and infiltrate every aspect of life. Why It Matters : Bezos’ strategy for Amazon’s success is not only simple but also effective. By focusing on a few key areas, the company can ensure it stays on track and continues to grow. The emphasis on AI, in particular, shows that Amazon is looking to the future and is ready to innovate and adapt to new technologies. This forward-thinking approach is likely to play a crucial role in Amazon’s continued success and growth. Read Next Jeff Bezos Swears By This One-Hour Rule For Success — Now Neuroscience Backs It Up This content was partially produced with the help of AI tools and was reviewed and published by Benzinga editors. © 2024 Benzinga.com. Benzinga does not provide investment advice. All rights reserved.Three judges have put their names in for consideration for the empty associate justice position on the state's highest court. District Court Judges David Bargen of Adams and Jason M. Bergevin of Columbus and Nebraska Court of Appeals Judge Lawrence Welch Jr. of Plattsmouth have submitted applications for appointment to the seat on the Nebraska Supreme Court made vacant by current Chief Justice Jeff Funke's appointment to that role Nov. 1. A public hearing of the Judicial Nominating Commission will be at 10 a.m. Dec. 12 at the Hamilton County Courthouse in Aurora. The commission will hear from each of the applicants and ask them questions at that time. Southwest fans Kylea Stritt (from left), Peg Rice, and Stacey Wilson cheer on their team as the "horsemen" during a Class D-1 first-round match Thursday at Pinnacle Bank Arena. Millard West players dogpile on the floor after defeating Lincoln Southwest in five set match during a Class A first-round match Wednesday at Pinnacle Bank Arena. Lincoln Southwest's Shelby Harding dives to save the ball from hitting the ground in the first set during a Class A first-round match Wednesday at Pinnacle Bank Arena. Second graders Eli Gonzalez (left) and Shrutoshome Datta look at drawings that first and second grade students made at the Monster Jam Art Show on Wednesday at Elliott Elementary School. The elementary school students made drawings of monsters to be turned into different types of art by Lincoln High School students. Norris players celebrate a point against Lincoln Pius X in a Class B state volleyball tournament match, Wednesday, Nov. 6, 2024, at Pinnacle Bank Arena. U.S. Sen. Deb Fischer (right) talks with supporters, including Darlene Starman of Lincoln, at her campaign office on Tuesday in Lincoln. A cutout of Jesus watches over voters on Tuesday at Redeemer Lutheran Church in Lincoln. Katie Goeling (left) fills out her ballot while her son Gunner, 4, holds her hand during Election Day on Tuesday at St. Paul's Lutheran Church in Malcolm. Abigail Webb votes on Tuesday at F Street Community Center. Nebraska's Rollie Worster (24) shoots a layup while defended by Texas Rio Grande Valley's Marshal Destremau (left) and Trey Miller (right) during the first half of the game on Monday, Nov. 4, 2024, at Pinnacle Bank Arena. Nebraska's Allison Weidner (left) autographs a poster for Freeman Public Schools student Godwil Muthiani, 12 (center), after the game against UNO on Monday, Nov. 4, 2024, at Pinnacle Bank Arena. Muthiani's sign says, "#3 Allison Weinder is the GOAT! Sorry I'm only 12." Nebraska Head Coach Matt Rhule speaks to an official after a targeting call on Nebraska during the first quarter of the game against UCLA on Saturday, Nov. 2, 2024, at Memorial Stadium. The call was overturned after review. Nebraska's Dante Dowdell scores against UCLA in the fourth quarter on Saturday at Memorial Stadium. Cadet Elena Burgwald (left) and Cadet Mason Beck look up as a B-1B Lancer flies over Memorial Stadium before the UCLA game against Nebraska on Saturday. UCLA's K.J. Wallace (7) defends Nebraska's Jacory Barney (17) as he makes a diving 40-yard catch in the second quarter on Saturday, Nov. 2, 2024, at Memorial Stadium. Lincoln Southeast quarterback Tre Bollen (left) and Tate Sandman react after losing a Class A football playoff game against Millard North on Friday, Nov. 1, 2024, at Seacrest Field. Millard North won 10-3. After the field clears, Norris' Jarrett Behrends (17) kicks his helmet after the Titans fell to Waverly 16-17 in a Class B football playoff game on Friday, Nov. 1, 2024, at Waverly High School. A line of people waiting to vote has been normal at the Lancaster County Election Commission Office at 601 N. 46th St., as it was Friday afternoon. The office will be open 7 a.m. to 5 p.m. Monday to allow voters to cast an early ballot. If they wait until Election Day, they will need to go to their precinct or drop off their ballots at one of five drop boxes across the city. For more stories about about Tuesday's election, go to Journalstar.com . Iris Gonnerman, 8 (from right), her brother Oliver, 6, and cousin Noreen Milana, 9, wave flags while watching Veterans Parade outside the state Capitol on Sunday. Nebraska's Connor Essegian scores against Bethune-Cookma on Saturday, Nov. 9, 2024, at Pinnacle Bank Arena. Lincoln Lutheran players embrace one another as threy celebrate defeating Thayer Central in four sets to win the Class C-2 championship match Saturday at the Devaney Sports Center. Covered by a canopy of changing leaves, a car cruises along A street in a neighborhood north of Downtown Lincoln on Tuesday, Nov. 12, 2024. Mild temperatures continue into the mid weeks of November. Wednesday calls for a chance of rain showers before noon with gusty winds. Most days this week are expected to be accompanied by mostly sunny skies and consistent breezes. Norris' Anna Jelinek (left) lifts the the Class B championship trophy alongside Rya Borer on Saturday at the Devaney Sports Center. Superior players celebrate their three set win over EMF during the Class D-1 championship match Saturday at the Devaney Sports Center. Reflected in a ceiling beam, Leyton takes on Shelton in the first set of the Class D-2 championship match Saturday at the Devaney Sports Center. Omaha Skutt's Nicole Ott (left) and Addison West react after a point in the second set during a Class B semifinal match Friday at Pinnacle Bank Arena. Hasan Khalil, owner of Golden Scissors, trims the beard of Vitaliy Martynyuk on Friday at his barbershop in Lincoln. Second-time mother giraffe Allie nuzzles her new calf in the giraffe experience enclosure on Friday, Nov. 15, 2024, at the Lincoln Children's Zoo. Nebraska celebrates during the first set of the match against Minnesota on Thursday at the Devaney Sports Center. A Lincoln firefighter sprays water on to the roof from a ladder truck as they battle a fire at the former Village Inn at 29th and O streets the morning of Wednesday, Nov. 20, 2024. Luca Gustafson, 6, rides to school Tuesday with the bike bus at Riley Elementary School. Each Tuesday, students can bike to school with adult chaperones along a specific route. Wahoo's Braylon Iversen celebrates with Warrior players after they defeated Auburn in a Class C-1 state semifinal game Friday in Wahoo. Lincoln Fire Fighters Association member Andy Evans works to assemble a headboard during a bed-building day hosted by Sleep in Heavenly Peace on Saturday at Hampton Enterprises. Volunteers helped build 20 beds for children in need. District Judge Jason Bergevin Court of Appeals Judge Lawrence Welch Jr. District Judge David Bargen Reach the writer at 402-473-7237 or lpilger@journalstar.com . On Twitter @LJSpilger Get local news delivered to your inbox! {{description}} Email notifications are only sent once a day, and only if there are new matching items.

How you’ve been making mashed potatoes TOTALLY wrong – stop boiling them in water if you want it extra creamy

Brad Pitt pops champagne with Javier Bardem and gets behind the wheel at Formula One race while filming F1Global Social Networking App Market To Reach $207.31 Billion By 2028 With A Growth Rate Of 28.3%

1 2 Bhubaneswar: After receiving ground penetrating radar and GPS survey report of Ratna Bhandar of the Puri Jagannath Temple , the Shree Jagannath Temple Administration (SJTA) on Saturday urged Archaeological Survey of India (ASI) to immediately undertake repair, maintenance and conservation work of the treasury. The 45-page technical report was prepared with the assistance of National Geophysical Research Institute, Hyderabad. The report gives a detailed account of the present condition of the walls and floors of Ratna Bhandar. "In a letter to ASI we have requested it to start the repair and conservation work at the earliest," said Arabinda Padhee, chief administrator of SJTA. Padhee stated that the temple administration would extend full cooperation to ASI in this endeavour. "Based on the report, we have requested ASI to share the repair plan and discuss it with the temple management. We will consult with the Chhatisa Nijog regarding the plan for the repair of Ratna Bhandar. At the same time, we requested ASI that during the repair work there should be no disruption to rituals and darshan of the deities," Padhee said. The ASI had conducted a detailed survey using the latest technology and equipment, including laser scanning and ground penetrating radar survey in Sept and detected cracks within the treasury. However, no secret tunnels or chambers were found in Ratna Bhandar. The valuables of inner and outer chambers of Ratna Bhandar were shifted to a temporary strongroom in two phases in July. Maharashtra Jharkhand Maharashtra Alliance View i Party View Seats: 288 Results Majority: 145 BJP+ 229 MVA 47 OTH 12 Results : 288 / 288 BJP+ WON Jharkhand Alliance View i Party View Seats: 81 Results Majority: 41 INDIA 56 NDA 24 OTH 1 Results : 81 / 81 INDIA WON Source: PValue "After the repair and conservation work of Ratna Bhandar is over, the inventory process will start in accordance with the temple's established rules. Digitisation of the whole process will be done," said Padhee.KABUL (Amu Tv): Food insecurity in Afghanistan remains a pressing concern as 14.8 million people are projected to face critical shortages during the winter months, the UN International Children’s Emergency Fund (UNICEF) said. The figure accounts for 32 percent of the Afghan population, who will require urgent humanitarian food assistance from November 2024 to March 2025. UNICEF’s report underscores the challenges facing the nation, citing a fragile economy, limited access to basic services, and the lingering effects of 40 years of conflict. These issues are compounded by natural disasters, climate shocks, and shifting political dynamics in the region. Afghan returnees face heightened challenges The humanitarian crisis is exacerbated by the ongoing influx of Afghan returnees from Pakistan. Since mid-September 2023, more than 758,000 individuals have been registered crossing back into Afghanistan. UNICEF has been providing aid at border points like Torkham and Spin Boldak, offering health services, polio vaccination campaigns, clean water and sanitation (WASH), nutrition programs, and child protection interventions. “UNICEF continues to support the response,” the report stated, emphasizing the agency’s efforts to mitigate the growing humanitarian challenges. Voices of Hardship The report also highlighted the human toll of the crisis, with individuals like Mahboba, a former employee of a private organization in Badghis, offering a glimpse into life under Taliban rule. “For five or six years, I worked and earned 21,000 Afghanis a month. I was the sole breadwinner for my family,” she said. “But for the past two years, the Taliban have prohibited me from working. Now, I can’t even provide one meal a day for my children.” Mahboba, who cares for a family of five, described the winter as a season of unbearable sorrow. “We don’t have proper food to eat. Winter has come, and we don’t know what to eat, what to wear, or what to do. There is absolutely no way forward,” she said. Others share similar struggles. In Herat, a resident described waiting in vain for work each day. “There are eight people in my family, and there’s no labor available,” he said. “The price of rice, oil—everything—has gone up. We can’t afford it.” Abdullah, a resident of Kabul, spoke of the desperate measures families are taking. “I dismantled my chair to keep my forty-day-old baby warm because we don’t have coal,” he said. “Since morning, I’ve only earned ten Afghanis. How can we survive this way?” Shrinking aid amid funding shortages The World Food Programme (WFP) has warned that the situation may worsen, as millions of Afghans are set to endure a harsh winter without adequate food assistance. Severe funding shortages mean the agency will only be able to support six million people this winter, leaving millions more without help. UNICEF noted that Afghanistan remains the second-largest humanitarian crisis in the world, with more than half the population in need of aid. While conflict has subsided, the drivers of need have shifted toward economic hardship and climate-induced shocks, compounded by significant operational barriers for aid organizations. As Afghans face another winter of struggle, the international community’s ability to sustain critical aid programs is being stretched thin, raising concerns about the nation’s long-term recovery prospects.

Program Announced at Rutgers Men's Basketball Game as Part of LG's Life's Good Night PISCATAWAY, N.J. , Dec. 16, 2024 /PRNewswire/ -- LG Electronics USA , a proud partner of Rutgers Athletics, announced the creation of two positions in its annual LG Summer Internship Program exclusively for Rutgers student-athletes. The announcement was made at a recent Rutgers men's basketball game, which also featured a series of Life's Good giveaways for fans, including LG TVs and LG XBOOM Audio products. As part of the company's commitment to fostering young talent, interns will have the chance to work alongside experienced professionals, gaining exposure to various areas of LG's organizations and making important contributions to real-world projects as part of the internship program. "LG is a very meaningful and impactful place to work," said Audrey Cha , a junior at Rutgers and former LG brand marketing summer intern who was on hand to help make the announcement. "I'm really passionate about the field of marketing, and my internship allowed me to experience a lot of real-world work in my field. I was also able to make a lot of connections that I've maintained even after my internship ended," she added. LG also added multiple Life's Good moments throughout the game for the fans. As part of the company's sponsorship, LG brought "Life's Good" to center court at Jersey Mike's Arena with a friendly head-to-head competition and product giveaways. Following the game, fans enjoyed a meet-and-greet with Rutgers guard and team captain, Jeremiah Williams . "LG recognizes the importance of investing in the next generation of leaders, and our internship program provides a unique opportunity for students to gain enriching experiences in a variety of fields in a dynamic corporate environment," said Louis Giagrande , LG USA head of marketing. "We are proud to partner with Rutgers Athletics to support their student-athletes both on and off the court." "LG's summer internship program continues to create exceptional opportunities for our student-athletes," said Carey Loch , Senior Associate Athletic Director for Student-Athlete Development and Success at Rutgers University . "The presence of LG at this game had a powerful impact, energizing fans, strengthening the LG-Rutgers partnership and showcasing LG's investment in our students' futures." In addition to highlighting the internship program, the halftime competition featured a head-to-head challenge where fans tested their basketball shooting skills for a chance to win LG prizes. During the post-game meet and greet with Williams, fans also had the opportunity to take pictures, get his autograph and win LG products including XBOOM XL7 and XBOOM XG2T portable audio speakers. To learn more about LG's commitment to student-athletes, visit https://www.lg.com/us/ncaa . About LG Electronics USA LG Electronics USA , Inc., based in Englewood Cliffs, N.J. , is the North American subsidiary of LG Electronics, Inc., a $68 billion global innovator in technology and manufacturing. In the United States , LG sells a wide range of innovative home appliances, home entertainment products, commercial displays, air conditioning systems and vehicle components. LG is an 11-time ENERGY STAR® Partner of the Year. The company's commitment to environmental sustainability and its "Life's Good" marketing theme encompass how LG is dedicated to people's happiness by exceeding expectations today and tomorrow. www.LG.com . Media Contacts: LG Electronics USA Chris De Maria [email protected] 908-548-4515 Kristi Hubert [email protected] 630-995-5444 SOURCE LG Electronics USA