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WALTHAM, Mass. , Nov. 25, 2024 /PRNewswire/ -- Spyre Therapeutics, Inc. (NASDAQ: SYRE), a clinical-stage biotechnology company utilizing best-in-class antibody engineering, rational therapeutic combinations, and precision medicine approaches to target improved efficacy and convenience in the treatment of Inflammatory Bowel Disease ("IBD"), today announced that will participate in a fireside chat and investor meetings at the 7th Annual Evercore ISI HealthCONx Conference. Details of the fireside are as follows: To access this webcast, please visit the "Events & Presentations" page within the Investors section of the Spyre website at ir.spyre.com . An archive of the webcast will be available for replay following the end of the conference. About Spyre Therapeutics Spyre Therapeutics is a clinical-stage biotechnology company that aims to create next-generation inflammatory bowel disease (IBD) products by combining best-in-class antibody engineering, rational therapeutic combinations, and precision medicine approaches. Spyre's pipeline includes extended half-life antibodies targeting α4β7, TL1A, and IL-23. For more information, visit Spyre's website at www.spyre.com . Follow Spyre Therapeutics on social media: @spyretx and LinkedIn View original content to download multimedia: https://www.prnewswire.com/news-releases/spyre-therapeutics-to-participate-in-the-7th-annual-evercore-isi-healthconx-conference-302315865.html SOURCE Spyre Therapeutics, Inc.San Francisco 49ers quarterback Brock Purdy will miss Sunday's game against the Packers with a sore throwing shoulderhttps www mnl777 co member promotion apply

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Has there ever been a more eagerly-anticipated League of Ireland campaign? We head into 2025 knowing for certain that history will be made on a number of fronts, and believing the record books can be rewritten elsewhere too. For the first time since the birth of European club football, an Irish outfit is still involved post-Christmas, with Shamrock Rovers set for a February Europa Conference League knockout clash with Molde. READ MORE: Damien Duff's decision not to impose 'ridiculous' booze ban is reaping rewards READ MORE: The good, the bad and the ugly of Ireland's international year Despite their 2022 home and away defeats to the Norwegians, the Hoops will fancy their chances of making the last-16 and adding to their unprecedented €6.5m earnings to date. In between the away and home legs, Rovers will be involved in another big first for the League of Ireland - a Dublin derby against Bohemians at the Aviva Stadium. Interest in that one is expected to be huge, with the two cross-city rivals kicking off their campaigns in a fixture unparalleled in the Irish game. That game, taking place in a 50,000-capacity stadium, could be the perfect platform to set more records in 2025. The 2024 season saw attendances at games involving League of Ireland clubs hit one million-plus for the first time ever. In total, 1,001,630 fans walked through turnstiles up and down the land to watch games in the men's Premier Division and First Division, women’s Premier Division, men's and women's FAI Cups, the All-Island Cup and in Europe. The pressure is now on to beat that number and keep the interest in the game here growing. If all goes to plan, 2025 will be the last season for the historic Dalymount Park as we know it. That fact alone should be enough to guarantee full houses every other weekend. It is expected that redevelopment work will begin in 2026, with Bohs moving to a temporary home while their new 8,000-capacity UEFA Category Three stadium is built. The Dalymount project was the biggest recipient of money in a historically generous Large Scale Sports Infrastructure Fund (LSSIF) handout to League of Ireland sides in November. The €24.7m awarded to the Phibsborough redevelopment dwarfed the massive €16.4m given to Sligo Rovers for their own ambitious stadium plans, while Wexford received €2m. Millwall were the latest club to take a close look at Stephen Bradley’s remarkably successful spell as Shamrock Rovers manager - and it’s only a matter of time before the Hoops are on the lookout for a new manager. Our prediction is that a different man will be in the dugout by the end of 2025. Bradley has achieved everything in the Irish game, winning four Premier Divisions and an FAI Cup. He is the first manager to qualify for two European group stage campaigns and to lead a club into the new year knockout rounds. “I have had a number of approaches over the last 18 months from clubs, but I have also made it very clear that my son has been battling cancer and that’s my number one priority and has been,” said Bradley last week when quizzed on the Millwall interest. He added that brave Josh was “nearly finished” his three years of treatment. As for their next manager? We could see former midfielder Stephen Rice - with Premier League (Crystal Palace) and international (Ireland) coaching experience - fitting into the role. First off, the biggest lesson to take from 2024 should be - write off Damien Duff at your peril. Right from when he first took the Shelbourne job, folk were suggesting that he wouldn’t last the course. Three seasons later, he delivered the biggest prize in Irish football. Even on their way to glory, predictions that they would fall away were plentiful, but when it came to the crunch they delivered. With five minutes to go on the final night, Shamrock Rovers were on course for a historic five-in-a-row, but up popped Harry Wood with a title-clinching goal at the Ryan McBride Brandywell. 2025 will be even tougher for Duffer and his players. Derry City are under new management, with Tiarnan Lynch coming in after winning two NIFL Premierships with Larne, and securing a first ever European group/league phase qualification for a Northern Irish side. Rovers are on a mission to reclaim their crown and St Patrick’s Athletic are on the ascendancy under Stephen Kenny. If last year’s title race was tight, 2025 could deliver an even tenser finale. Shelbourne are going through something of a title drought in the women’s game, with Peamount United and current champions Athlone Town claiming League of Ireland gold in the last two seasons. Their FAI Cup crushing of Athlone, who subsequently lost manager Ciaran Kilduff, may well be a sign of things to come as Eoin Wearen’s side aim for a return to the top. Premier Division: St Patrick’s Athletic FAI Cup: Shamrock Rovers European qualification: Shelbourne and Derry City Relegation: Cork City Women’s Premier Division: Shelbourne Women’s FAI Cup: Galway United Get the latest sports headlines straight to your inbox by signing up for free email alerts .

HIV stigma can now be more dangerous than the virus—research shows how to address this'I felt like I was walking on eggshells': Family violence 'under-reported, under-prosecuted'Touchless trash cans are one of the latest innovations in automated kitchen technology. They use infrared motion sensors to automatically lift the lid, allowing users to dispose of trash without touching the can. This hands-free operation makes them not only efficient and easy to use but also improves kitchen hygiene as it helps reduce contact with germs, bacteria and parasites that are often found in household waste. Choosing the ideal touchless trash can for your home will depend on several factors, from the number of people in your household to the shape, size and material that best suits your decor. As with regular trash cans, there are many different shapes and styles available. The most common shapes are round, oval, square or rectangular. While shape can play a factor in determining which trash can to get, it is more important to find the right size trash can for your space. A 13-gallon trash can is standard for a kitchen. However, a smaller 5- to 10-gallon option would be better if you want to place it in a cabinet. For large families that generate a lot of waste, a larger 20 to 30-gallon trash can may be preferable. The most common materials are either metal or plastic. While plastic is certainly the cheaper option, metal trash cans are more durable. A stainless steel trash can is a good option, as it will match kitchen appliances and won’t rust or tarnish with time. However, metal trash cans are more pricey, retailing between $100 and $200, depending on their size and features. There are only two choices when it comes to a power source: battery or mains. A mains-powered trash can requires a permanent power source, restricting its location options. Battery-powered trash cans can be placed wherever you like and are particularly suitable for bathrooms. Look for a model that gives a warning when the batteries need replacing to avoid any inconvenience. The features of a trash can significantly impact the price, so it is important to decide which features you would like. Some trash cans have carbon filters that absorb unpleasant odors; however, remember that the filters must be replaced periodically. Other trash cans may feature a locking mechanism, which is handy if you have pets or small children because the lid will remain closed even if it’s knocked over. An elegant-looking option available in a range of metallic and colored finishes. It has a smooth and quiet motor. The surface is protected with an antimicrobial coating that inhibits the growth of bacteria. : At 36 inches tall, it’s too big to fit inside a cabinet. It is available in a range of shapes and sizes, and it has a fingerprint-proof stainless steel body. A choice of either battery or mains power provides versatility. It has a built-in natural carbon odor filter and a lockable lid. : It doesn’t come with batteries or a mains adapter. With a 4-gallon capacity, this trash can is ideal for use in a kitchen cabinet or a bathroom. It effectively filters odors and comes with a lemon-scented fragrance cartridge. : Although the body is made from metal, the lid is made from plastic, so it may not be as durable. This versatile option makes separating your recyclables from your waste easy because it has two removable inner buckets with handles. This trash can can be powered by batteries or an AC adapter. It can be easily moved around the kitchen with optional casters. : The battery compartment is below the trash level, so you need to be careful to avoid getting the batteries wet.

Arcane’s Showrunner Discussed Spinoff Plans Following The Series Finale, And There’s One Particular Project I’m Really Pumped For

WALTHAM, Mass. , Nov. 25, 2024 /PRNewswire/ -- Spyre Therapeutics, Inc. (NASDAQ: SYRE ), a clinical-stage biotechnology company utilizing best-in-class antibody engineering, rational therapeutic combinations, and precision medicine approaches to target improved efficacy and convenience in the treatment of Inflammatory Bowel Disease ("IBD"), today announced that will participate in a fireside chat and investor meetings at the 7th Annual Evercore ISI HealthCONx Conference. Details of the fireside are as follows: Tuesday, December 3, 2024 , at 7:30 a.m. Eastern time To access this webcast, please visit the "Events & Presentations" page within the Investors section of the Spyre website at ir.spyre.com. An archive of the webcast will be available for replay following the end of the conference. About Spyre Therapeutics Spyre Therapeutics is a clinical-stage biotechnology company that aims to create next-generation inflammatory bowel disease (IBD) products by combining best-in-class antibody engineering, rational therapeutic combinations, and precision medicine approaches. Spyre's pipeline includes extended half-life antibodies targeting α4β7, TL1A, and IL-23. For more information, visit Spyre's website at www.spyre.com . Follow Spyre Therapeutics on social media: @spyretx and LinkedIn SOURCE Spyre Therapeutics, Inc.West Ham 2-0 Newcastle (26 Nov, 2024) Game Analysis - ESPN

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