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DETROIT — Detroit and Green Bay, longtime rivals and current contenders, will have much at stake when they meet Thursday night in the Motor City. The NFC-leading Lions (11-1) are aiming to stay ahead of Philadelphia (10-2) in the race for the conference's best record and Minnesota (10-2) in the NFC North with a win against the Packers. Detroit can also clinch a spot in the playoffs with an 11th straight victory that would set a franchise record. “We’re in playoff football right now,” Lions coach Dan Campbell said. “This is the type of stuff that you live for and it’s also the type of stuff that gets you ready for the tournament.” Green Bay (9-3) also has a lot to play for because it can pull within a game of the Lions if it can split the season series with a slight upset as 3 1/2-point underdogs, according to BetMGM. “This game is going to be important for us moving forward toward the end of this thing and we’re going to treat it as such,” Packers safety Xavier McKinney said. Born to run Green Bay’s ability to slow down Detroit’s run game might be pivotal. Jahmyr Gibbs and David Montgomery, the first teammates in league history to run for at least 10 touchdowns in consecutive seasons, have combined to average more than 140 yards on the ground per game. The Packers limited San Francisco's Christian McCaffrey to 31 yards on 11 attempts and held Miami to 39 yards rushing in their past two games. It was the first time since 1995, and just the second time since 1950, that they gave up fewer than 45 yards rushing in two straight weeks. Montgomery ran 17 times for 73 yards and Gibbs had 65 yards rushing and a touchdown on 11 carries last month at Green Bay. “They played Montgomery the whole first half and then the second half they came with Gibbs,” McKinney recalled. “They got a good 1-2 punch.” Road warriors Home field has not been an advantage in the series lately. The road team has won four straight games, going back to Detroit closing the 2022 regular season and Aaron Rodgers' career with the Packers in a 20-16 win at Lambeau Field. Green Bay has won five straight NFC North road games, including last year at Detroit on Thanksgiving. Picked off McKinney and Lions safety Kerby Joseph each have an NFL -high seven interceptions, leading the rest of the league by at least two. Joseph had a pick-6 in the most recent meeting against Green Bay and has picked off four passes in four games against the Packers. “He’s a ballhawk,” Packers quarterback Jordan Love said. “He’s going to make the plays when the ball’s in the air, so he’s definitely a guy you’ve got to know where he’s at.” Social media slipup Lions coach Dan Campbell was taken aback at a news conference recently when a reporter informed him Gibbs had a post on social media showing some of the team's strategy. “I'd rather our stuff not be out there,” Campbell said. Green Bay coach Matt LaFleur feels the same way, though he said it doesn't provide a competitive edge to see another team's terminology on a whiteboard. “Guys understand that nobody wants their information out there for the whole world to see, so we try to keep everything in house here,” LaFleur said. “But I don’t think it’s like the end of the world, either.” Tough stretch Both teams will play a third game in 12 days. “How the whole organization has handled this has been really impressive,” said Packers defensive lineman Lukas Van Ness, who had a sack in each of his past two games. After the game, each team will get a break. The Lions will host the AFC East champion Buffalo Bills on Dec. 15 and Green Bay plays at Seattle later that night.Closing marks second significant acquisition from RA Capital's Raven incubator in 2024, and first acquisition of a company built by Raven from a technology platform in-licensed from a large pharmaceutical company BOSTON , Dec. 11, 2024 /PRNewswire/ -- RA Capital Management, LP (RA Capital), a multi-stage investment manager dedicated to evidence-based investing in public and private healthcare, life sciences, and planetary health companies, today announced that AbbVie has closed its $1.4 billion acquisition of RA Capital's portfolio company Aliada Therapeutics. Aliada's lead investigational asset is ALIA-1758, an anti-pyroglutamate amyloid beta (3pE-Aβ) antibody, which is in development for the treatment of Alzheimer's disease and is currently in a Phase 1 clinical trial. ALIA-1758 utilizes a novel blood-brain barrier-crossing technology that enhances delivery of targeted drugs into the central nervous system. Johnson & Johnson (through its venture capital arm, Johnson & Johnson Innovation – JJDC, Inc.), RA Capital, and Raven (RA Capital's healthcare incubator) co-founded Aliada and co-led the series seed financing in 2021 to advance the MODELTM platform created by Johnson & Johnson scientists that was licensed to Aliada at its inception. "Congratulations to the Aliada and AbbVie teams and our fellow investors on the close of this transaction," said Joshua Resnick , MD, Senior Managing Director at RA Capital Management and former board director at Aliada. "The acquisition of Aliada is the second significant acquisition of a Raven-grown company this year, joining Novartis' $1 billion upfront acquisition of radiopharmaceutical developer Mariana Oncology in May." "Delivering therapeutics across the blood-brain barrier with a low-volume, subcutaneous injection would be revolutionary for treating Alzheimer's disease and other neurological disorders, and has long been a dream in the field," said Laura Tadvalkar , PhD, Managing Director at RA Capital Management and former board chair at Aliada. "We look forward to following ALIA-1758's progress through the clinic, as AbbVie advances this important medicine for Alzheimer's disease patients." About Raven Raven is RA Capital Management's healthcare incubator. Raven's experienced team of scientists, operators, and innovators bring deep sector expertise, insight and executional capabilities across therapeutics, diagnostics, devices, and services. Raven builds companies: from originating and incubating new ideas to accelerating compelling innovations and rejuvenating promising assets. About RA Capital Founded in 2004, RA Capital Management is a multi-stage investment manager dedicated to evidence-based investing in public and private healthcare, life sciences, and planetary health companies. RA Capital creates and funds innovative companies, from private seed rounds to public follow-on financings, allowing management teams to drive value creation from inception through commercialization and beyond. RA Capital's knowledge engine is guided by our TechAtlas internal research division, and Raven, RA Capital's company creation team, offers entrepreneurs and innovators a collaborative and comprehensive platform to explore the novel and the re-imagined. RA Capital has more than 175 employees and over $10 billion in assets under management. The companies presented herein were selected to demonstrate a potential successful outcome of a company being incubated within our Raven incubator. They are not intended to represent a complete picture of RA Capital's portfolio, its exposures, risks or potential for positive or negative returns. Past performance is not indicative of future results. SOURCE RA Capital Management, LP
The possibility of NVIDIA facing significant fines stems from allegations of antitrust practices and violations in various regions, including China. Antitrust regulators in China have been increasingly vigilant in recent years, closely monitoring the activities of foreign companies operating within the country's borders. Given NVIDIA's substantial market share and influence in the graphics processing and AI industries, any findings of antitrust violations could have severe financial implications for the company.Two upcoming events in the Township of Leeds and the Thousand Islands have been deemed as municipally significant. The reason is for the purposes of the Alcohol and Gaming Commission of Ontario’s (AGCO) Special Occasion Permit process. This took place during Monday’s Township of Leeds and the Thousand Islands council meeting in Lansdowne. The first designation was given for the Small Halls Music Event scheduled for Jan. 25. This will be hosted by the Seeley’s Bay Area Residents’ Association (SBARA). Alcohol will be served at the event and Small Halls has been advertising the event on its website, while SBARA has been advertising the event on its social media pages. Now that council has chosen to pass the resolution deeming the event municipally significant, the clerk will provide a letter to SBARA to support their application to the AGCO. Council also deemed the Comedy Night hosted by the St. Lawrence District Medical Centre scheduled for Feb. 22 as municipally significant for the same process. The request for the designation was made by the St. Lawrence District Medical Centre. The object of the comedy event is to fundraise to support the medical centre and to allow community members to enjoy an evening of entertainment. Keith Dempsey is a Local Journalism Initiative reporter who works out of the Brockville Recorder and Times. The Local Journalism Initiative is funded by the Government of Canada.Traditionally, pharmaceutical group purchasing in China has been subject to rigid evaluation methods that often prioritize price over quality. This has led to a situation where healthcare providers are incentivized to choose the cheapest option, regardless of the overall value and effectiveness of the pharmaceutical products. As a result, many pharmaceutical companies have had to lower their prices in order to compete, leading to concerns about the quality and safety of the products being purchased.The FTC's actions send a strong message to companies operating in the gaming industry that deceptive practices will not be tolerated, and that consumers' rights must be protected. By holding Epic Games accountable and providing restitution to affected players, the agency is working to restore trust and integrity in an industry that has faced increasing scrutiny over its marketing tactics.
As we eagerly await the arrival of Death Comes 6, let's take a moment to appreciate the legacy of this groundbreaking franchise. From its humble beginnings to its status as a global phenomenon, Death Comes has left an indelible mark on the world of horror cinema. Here's to another 25 years of scares, thrills, and unforgettable moments with Death Comes.
‘Rigging is a crime’: Jake Paul’s scathing response to ‘insulting’ rumours after Mike Tyson fightThe recent update has introduced a wealth of new content, including new levels, weapons, enemies, and gameplay mechanics. Players are now able to explore even more of the mystical world of Black Myth, uncovering hidden secrets and confronting powerful foes along the way. The game's intricate level design and challenging combat system have kept players on the edge of their seats, eager to master every new challenge that comes their way.
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