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How many outdoor Christmas lights do I need? An expert electrician explains the 'fifty-per-foot' ruleBefore being elected as the first transgender woman to the US Congress, 34-year-old Sarah McBride said she expected hostility. A harsh national spotlight has fallen swiftly upon her. "They may try to misgender me, they may try to say the wrong name, they will do what we can predictably assume they might do," she told the TransLash podcast last month ahead of her resounding election victory on November 5. "They are going to do that to get a rise out of me and my job will be to not give them the response they want," the Democrat from Delaware explained. Ahead of her arrival in the House of Representatives on January 3, McBride was targeted by a resolution this week from a right-wing Republican colleague that would ban transgender women from women's toilets in the Capitol. "Just because a Congressman wants to wear a mini skirt doesn’t mean he can come into a women’s bathroom," South Carolina firebrand Nancy Mace wrote on social media as she led a highly personal campaign against McBride. House Speaker Mike Johnson, after initially seeking to buy time to debate the issue, came out in support of a ban, saying that all single-sex facilities would be "reserved for individuals of that biological sex." McBride -- who wears knee-length dresses, not miniskirts -- issued a statement saying that she said would respect the rules "even if I disagree with them." "I'm not here to fight about bathrooms," said the politician and activist, who transitioned as a 21-year-old and told her parents on Christmas Day 2011. Donald Trump repeatedly raised transgender issues in the closing stages of his presidential campaign, with aides noting how questions around trans identity struck a nerve with swing voters. Two of the biggest issues -- at the heart of ongoing "culture wars" between conservatives and progressives -- are whether transgender women should be allowed in women's toilets and be admitted in women's sport. Mocking transgender athletes and "woke ideology," Trump promised to get "transgender insanity the hell out of our schools, and we will keep men out of women’s sports." McBride has long been an advocate for trans rights and she helped campaign for a law banning gender discrimination in her home state of Delaware, during which she was publicly called a "freak" and the "devil incarnate". "Listening to that was demeaning and dehumanizing for my child," her mother Sally told The Washington Post in a 2018 profile. "I still have a hard time coping with that." Undeterred, McBride rode the blows and was elected as the first US transgender state senator in 2020. She has been open about her mental health struggles growing up as a boy named Tim and the personal tragedy that has marked her life since, writing a memoir called "Tomorrow Will Be Different" in 2018. "I remember as a child praying in my bed at night that I would wake up the next day and be a girl," she told a TED talk in 2016. She first gathered major public attention with an open letter while a student leader at American University in Washington that announced her transition. She went on to encounter President Joe Biden and his family, also Delaware natives, when she became active in grassroots politics there. After interning at the White House under President Barack Obama, she secured an invitation to speak at the 2016 Democratic Party convention. The White House was also the scene of her first encounter with her late husband, Andrew Cray, a transgender man and LGTBQ+ activist. They married two years later shortly before Cray died from cancer. Knowing the attention she is destined for in the US Congress, she says her aim is to be an effective congresswoman focused on everyday voter priorities such as housing and inflation. But she knows she will be constantly pushed to be a spokeswoman -- and defender -- of the trans community. "I can't do right by the trans community if I'm not being the best member of Congress that I can be for Delaware," she told TransLash. "It's the only way that people will see that trans people can be good doctors, can be good lawyers, good educators, good members of Congress. I can't be there to put out a press release and tweet every time someone says something." adp/bgs
Tax evasion in sugar sector: FBR suspends 6 officials Technology installed as TTS and Hopper is meant to gauge real production of sugar and some other sectors This image released on March 3, 2022, shows the FBR building. — Facebook @Federal Board of Revenue/File ISLAMABAD: The Federal Board of Revenue (FBR) has suspended its six officials in different parts of the country for their alleged involvement in tax evasion in the sugar sector. googletag.cmd.push(function() { googletag.display('div-gpt-ad-1700472799616-0'); }); The Intelligence Bureau (IB) shared reports about these officials who were involved in facilitating certain sugar millers in evading taxes. After receiving reports from multiple avenues, the FBR suspended six officials. This was done after the board received compromised integrity reports from the IB and other sources, said the official. The Federal Board of Revenue (FBR) launched its operation against 10 sugar mills and identified five more throughout the country which were allegedly involved in selling sugar without passing through the Track and Trace System (TTS) and Hopper solutions. The technology installed as TTS and Hopper is meant to gauge the real production of sugar and some other sectors. But the FBR has found that certain sugar millers are involved in selling sugar without TTS stamps and passing through Hopper solutions. “We have taken action against ten sugar mills and halted their operations. Later, some of them resumed operation after paying the penalty amount,” a top official of FBR told The News here on Sunday. The official shared a video clip showing how the sugar packets are prepared without TTS and other technological solutions. For effective enforcement to plug leakages, the FBR has installed Track & Trace System (TTS) and Hopper Solution to gauge the real production of sugar mills across the country. The FBR had invoked Section 40-B of the Sales Tax Act and deputed around 300 officers on all sugar mills to monitor their production and curb billions of rupees tax evasion. The prime minister has approved powers to the Intelligence Bureau (IB) to keep strict surveillance over FBR’s designated monitoring officers on sugar mills as sales tax evasion of Rs40 billion on an annual basis is feared. The FBR has devised a three-pronged strategy, including invoking 40-B of sales tax for deputing monitoring officers at sugar mills, effective placement of Track and Trace System (TTS) and assignment of officers for further monitoring of deputed officers. Out of the total production of 6.7 million tons of sugar, the sales tax collected at a rate of 18 percent should fetch an amount of Rs130 to Rs140 billion on an annual basis. However, the FBR’s collection stands at around Rs90 to Rs100 billion, so there is a tax gap of Rs30 to Rs40 billion at least. There is not much input involved except sugarcane and electricity, so there is no other way but to ensure proper monitoring of production for avoiding tax evasion. One official said that the Track and Trace System was installed at 80 sugar mills but the FBR fears there is a possibility of sugar bags coming out without TTS stamps. It’s hard to explain because if the bags are without stamps, they could be seized. But there are chances that fake TTS stamps might be affixed to deceive the tax machinery. So, it needs proper scrutiny and enforcement as well as stern actions against those involved in such practices.ATLANTA — As she checked into a recent flight to Mexico for vacation, Teja Smith chuckled at the idea of joining another Women’s March on Washington. As a Black woman, she just couldn’t see herself helping to replicate the largest act of resistance against then-President Donald Trump’s first term in January 2017. Even in an election this year where Trump questioned his opponent’s race, held rallies featuring racist insults and falsely claimed Black migrants in Ohio were eating their neighbors’ pets, he didn't just win a second term. He became the first Republican in two decades to clinch the popular vote, although by a small margin. Supporters of Democratic presidential nominee Vice President Kamala Harris hold their fists in the air after she delivered a concession speech after the 2024 presidential election Nov. 6 on the campus of Howard University in Washington. “It’s like the people have spoken and this is what America looks like,” said Smith, the Los Angeles-based founder of the advocacy social media agency, Get Social. “And there’s not too much more fighting that you’re going to be able to do without losing your own sanity.” After Trump was declared the winner over Democratic Vice President Kamala Harris, many politically engaged Black women said they were so dismayed by the outcome that they were reassessing — but not completely abandoning — their enthusiasm for electoral politics and movement organizing. Black women often carry much of the work of getting out the vote in their communities. They had vigorously supported the historic candidacy of Harris, who would have been the first woman of Black and South Asian descent to win the presidency. Harris' loss spurred a wave of Black women across social media resolving to prioritize themselves, before giving so much to a country that over and over has shown its indifference to their concerns. AP VoteCast, a survey of more than 120,000 voters, found that 6 in 10 Black women said the future of democracy in the United States was the single most important factor for their vote this year, a higher share than for other demographic groups. But now, with Trump set to return to office in two months, some Black women are renewing calls to emphasize rest, focus on mental health and become more selective about what fight they lend their organizing power to. “America is going to have to save herself,” said LaTosha Brown, co-founder of the national voting rights group Black Voters Matter. She compared Black women’s presence in social justice movements as “core strategists and core organizers” to the North Star, known as the most consistent and dependable star in the galaxy because of its seemingly fixed position in the sky. People can rely on Black women to lead change, Brown said, but the next four years will look different. “That’s not a herculean task that’s for us. We don’t want that title. ... I have no goals to be a martyr for a nation that cares nothing about me,” she said. Supporters cheer during a community rally with Democratic presidential nominee Vice President Kamala Harris on Oct. 27 in Philadelphia. AP VoteCast paints a clear picture of Black women's concerns. Black female voters were most likely to say that democracy was the single most important factor for their vote, compared to other motivators such as high prices or abortion. More than 7 in 10 Black female voters said they were “very concerned” that electing Trump would lead the nation toward authoritarianism, while only about 2 in 10 said this about Harris. About 9 in 10 Black female voters supported Harris in 2024, according to AP VoteCast, similar to the share that backed Democrat Joe Biden in 2020. Trump received support from more than half of white voters, who made up the vast majority of his coalition in both years. Like voters overall, Black women were most likely to say the economy and jobs were the most important issues facing the country, with about one-third saying that. But they were more likely than many other groups to say that abortion and racism were the top issues, and much less likely than other groups to say immigration was the top issue. Despite those concerns, which were well-voiced by Black women throughout the campaign, increased support from young men of color and white women helped expand Trump’s lead and secured his victory. Politically engaged Black women said they don’t plan to continue positioning themselves in the vertebrae of the “backbone” of America’s democracy. The growing movement prompting Black women to withdraw is a shift from history, where they are often present and at the forefront of political and social change. One of the earliest examples is the women’s suffrage movement that led to ratification in 1920 of the 19th Amendment to the Constitution, which gave women the right to vote. Black women, however, were prevented from voting for decades afterward because of Jim Crow-era literacy tests, poll taxes and laws that blocked the grandchildren of slaves from voting. Most Black women couldn’t vote until the Voting Rights Act of 1965. Black women were among the organizers and counted among the marchers brutalized on the Edmund Pettus Bridge in Alabama, during the historic march in 1965 from Selma to Montgomery that preceded federal legislation. Decades later, Black women were prominent organizers of the Black Lives Matter movement in response to the deaths of Black Americans at the hands of police and vigilantes. In his 2024 campaign, Trump called for leveraging federal money to eliminate diversity, equity and inclusion programs in government and discussions of race, gender or sexual orientation in schools. His rhetoric on immigration, including false claims that Black Haitian immigrants in Springfield, Ohio, were eating cats and dogs, drove support for his plan to deport millions of people. Tenita Taylor, a Black resident of Atlanta who supported Trump this year, said she was initially excited about Harris’ candidacy. But after thinking about how high her grocery bills have been, she feels that voting for Trump in hopes of finally getting lower prices was a form of self-prioritization. “People say, ‘Well, that’s selfish, it was gonna be better for the greater good,''' she said. “I’m a mother of five kids. ... The things that (Democrats) do either affect the rich or the poor.” Where can Black women feel supported and flourish financially? When posed that question, Dr. Lori Martin, a professor of African and African American studies and sociology at Louisiana State University, had this to say: "A livable place for Black women is safe, and for women with children, it is home to schools where all students have access to an excellent education. It would also be diverse, with a visible and thriving Black community, including Black businesses." While the socioeconomic realities of our current time touch all corners of the country, there are pockets of the U.S. where the wealth gap narrows and Black women have more opportunities. MoneyGeek analyzed data on income, the cost of crime , homeownership , and poverty levels from 164 cities across the United States to rank the best — and worst — cities for Black women to live and financially flourish in. MoneyGeek ranked 164 cities with populations greater than 65,000 from the best to the worst for Black women. The ranking includes analysis of income, poverty rate, homeownership, educational attainment and health insurance gaps between Black women and the entire population nationally and locally. The size of the local Black population and the cost of crime in the area were included in the ranking to reflect the presence of the Black community and safety, respectively. Southfield — a suburb of Detroit — and Pearland — a Houston suburb — ranked as the top two cities in the analysis. Notably, Southern cities make up the majority of cities in the top 25, with 13 located in this region. In contrast, Minneapolis, Minnesota, ranked as the worst city for Black women. In Minneapolis, Black women face high poverty rates in absolute and relative terms and have low rates of health insurance coverage compared to the cities analyzed. Meanwhile, Miami ranks as the second least favorable city, with a significant local income gap — there, white men earn almost triple the income of Black women. Income disparity is a key measure of how well Black women are doing today. For each city in the analysis, we calculated the local Equal Pay Day — the day in the following year when Black women would make an equivalent amount as white men — using the median income of Black women working full time and the median income of white men working full time in each locality. In Carson, California, the median pay of Black women is higher than the median pay of white men. However, in Evanston, Illinois, Black women make just over a third of white men's earnings, meaning they would need to work until September 24, 2024, to earn the equivalent of a white man's 2022 pay. Economic challenges faced by Black women include restricted career advancement opportunities, insufficient health insurance, and inadequate retirement savings. Survey data from Goldman Sachs indicates that 42% of Black women perceive limited career growth opportunities compared to 35% of U.S. adults, and merely 43% are able to obtain health insurance through their employer, in contrast to 53% nationwide. Additionally, 71% of Black women feel they are living paycheck to paycheck, compared to 63% of the general population. The intersection of racial and gender bias contributes to these challenges, resulting in low-wage jobs and a considerable wealth gap. Our analysis validates this, demonstrating that Black women who work full-time, year-round, earn 64 cents for every dollar white men earn working full-time, year-round. Less access to economic opportunities puts Black women at a disadvantage in building wealth. The FDIC's National Survey of Unbanked and Underbanked Households found that 11.3% of Black households were unbanked compared to just 2.1% of white households. Unbanked households are credit invisible — that is, they don't have a credit history and, therefore, can't build credit. Having no credit history makes it difficult to utilize credit cards to manage cash needs and mortgages to buy homes. Advocating for economic opportunities for Black women The struggle for economic equity remains a persistent challenge for Black women in America, who have historically faced systemic wage disparities and employment obstacles. However, there are tools and resources that can provide Black women with economic opportunities and empowerment. Dr. Ukanwa shares additional solutions, such as: 1. Invest in education: Research has already shown that degrees increase lifetime earnings, close some societal gaps, and increase job security. But if degrees are not your path, it also means continuing to build that knowledge and expertise in something you can be the best at. Figure out your expertise and what you bring to the table. 2. After building your expertise in a field, build your reputation and personal brand: With an excellent reputation and personal brand, people will start to seek you out rather than the other way around. This increases the worth of your expertise. 3. Find out what your expertise is worth: Educate yourself on how to negotiate . Negotiate to be paid what you are worth. 4. Get into the habit of ownership: Build your own equity, which decreases the dependence on someone else for your income. For example, this could be your own business, stocks , or real estate. To rank the best cities for Black women, MoneyGeek analyzed data from the American Community Survey , MoneyGeek's Safest Cities and Safest Small Cities and Towns studies, and the Bureau of Economic Analysis. The analysis started with over 500 places in America with populations of 65,000 or more. Places without granular data about Black women or lacking other data points for the analysis were removed to get to the final set of 164 cities. The ranking of the best cities for Black women was based on eight factors: safety, Black population, educational attainment, poverty rates, income, employment, health insurance, and homeownership. Each factor was weighted equally and scaled to a score between 0 and 1. The factors were calculated as follows: Safety (full weight): This metric equally comprises two metrics. Percent of local population that is Black (full weight): This percentage represents the proportion of Black individuals within a city's total population, as reported by the United States Census Bureau's five-year American Community Survey (ACS) from 2021, the most recent data available. Educational attainment (full weight): This metric equally comprises two metrics. Poverty rate (full weight): The percentage point difference between the city's rate of Black women earning at or above the poverty level and the rate of all women living above the poverty level nationally. This finding comes from the 2021 Census ACS five-year data, the latest available source covering over 200 cities. Income (full weight): This factor equally comprises two metrics. Employment (full weight): The difference in percentage points between the Black female employment rate and the white male employment rate in the locality. Health insurance (full weight): This metric reveals the percentage point difference between Black women (ages 19-64) and white men (ages 19-64) with health insurance. This information comes from the Census ACS five-year data from 2021, the most recent data source available. Black female homeownership (full weight): This factor comprises three metrics. The full data set can be found here . This story was produced by MoneyGeek and reviewed and distributed by Stacker Media. Get local news delivered to your inbox!
Pep Guardiola sure 75 per cent of Premier League clubs want Man City relegatedTop-25 teams will hit the court across four games on Tuesday’s college basketball schedule. That includes the Wisconsin Badgers playing the Illinois Fighting Illini at State Farm Center. Check out the piece below for picks against the spread. Place your bets on any men’s college basketball matchup at BetMGM. Sign up today using our link. Bet on the Tennessee-Miami (FL) spread—or any other NCAA men’s basketball matchup—with BetMGM ! Bet on the Duke-Incarnate Word spread—or any other NCAA men’s basketball matchup—with BetMGM ! Bet on the Houston-Troy spread—or any other NCAA men’s basketball matchup—with BetMGM ! Bet on the Illinois-Wisconsin spread—or any other NCAA men’s basketball matchup—with BetMGM ! Not all offers available in all states, please visit BetMGM for the latest promotions for your area. Must be 21+ to gamble, please wager responsibly. If you or someone you know has a gambling problem, contact 1-800-GAMBLER .
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CHARLESTON, S.C. (AP) — KyKy Tandy scored 21 points and Florida Atlantic pulled away late in the second half to beat Oklahoma State 86-78 on Thursday in the Charleston Classic. It was the second straight loss by a Power Four team in the tournament after Miami fell to Drake in the opener. Florida Atlantic (4-2) plays the Bulldogs in the semifinals on Friday, while Oklahoma State (3-1) battles the Hurricanes in a consolation game. Leland Walker completed a three-point play with 4:38 left in the second half to give FAU its first lead, 68-67, since it was 16-14. Tandy made a 3-pointer from the corner to cap FAU’s 11-1 run for a 75-68 lead with 2:41 left. Oklahoma State went five-plus minutes without a field goal late in the second half until Brandon Newman made a fast-break layup with 1:17 remaining. But Ken Evans Jr. answered with a three-point play at the other end for a nine-point lead. The Cowboys turned it over on their next possession with 52.3 seconds left. Evans finished with 13 points, Walker scored 12 and Tre Carroll had 10 for FAU. The Owls attempted 49 free throws leading to three Oklahoma State players fouling out and three others finishing with four fouls. Khalil Brantley had 16 points and Robert Jennings II scored a career-high 14 points to go with 11 rebounds for Oklahoma State. Patrick Suemnick was helped off the floor with 1:40 left in the first half and did not return. Oklahoma State led 39-34 at halftime despite making just 33.3% of its shots. FAU shot a better percentage from the field (47.8) than at the free-throw line (46.7) in the first half. ___ Get poll alerts and updates on the AP Top 25 throughout the season. Sign up here . AP college basketball: https://apnews.com/hub/ap-top-25-college-basketball-poll and https://apnews.com/hub/college-basketballHow to Watch Top 25 Women’s College Basketball Games – Wednesday, November 27Like all major sports, college basketball has been affected by the transfer portal and the rise of NIL deals. Players aren't staying at schools, and those schools are moving to face new opponents. One program that's been able to manage the changes in the sport has been Houston, bucking the trends by keeping players on their roster well into their junior and senior seasons. That hasn't been the case for every player who's come through head coach Kevin Sampson's program, but doing things differently has produced results that are difficult to ignore. Sampson's program has created multiple first-round draft picks in the NBA, and one more elite player is now slated to head down to Houston next season. According to ESPN's Jeff Borzello , Chris Cenac is heading to the Cougars after announcing his commitment. Cenac is the No. 1 center in the class of 2025, and is Houston's highest-ranked recruit since 2007. NEWS: Chris Cenac, the No. 1 center in the 2025 class, just announced his commitment to Houston. He becomes the program's highest-ranked recruit since the ESPN recruiting database began in 2007 -- and vaults Houston's recruiting class to No. 2 in the country behind Duke. pic.twitter.com/zcUJ0MTJgk Borzello also says that Houston now has the second-best recruiting class in 2025, one behind the Duke Blue Devils. Since arriving at Houston in 2014, Sampson has taken the Cougars to the Final Four, along with one finish in the Elite Eight and two more in in the Sweet Sixteen. Houston has not been eliminated before the NCAA Tournament's second weekend since 2018, one of the best records of consistency in the country. Sampson and his team will look to win the Big 12 for the second year in a row after a first-place finish last season. They entered the tournament as the No. 1 seed in the South region, defeating Longwood and Texas A&M before losing to Duke in the Sweet Sixteen. This season, the Cougars are off to a 3-1 start, dropping a close game against No. 4 Auburn earlier this month. Houston is now set to compete in the Players Era Festival tournament in Las Vegas during Thanksgiving week, and they'll face No. 9 Alabama in another early-season matchup against one of the top teams in the SEC on Tuesday night. We'll see what Cenac and some of the other top recruits heading to Houston are able to do when they arrive on campus next year. Related: Dan Hurley Calls Out Officiating After UConn's Loss In Maui Monday
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Commanders-Saints Referee Says Critical Official Error 'Not Reviewable'Trump has promised again to release the last JFK files. But experts say don’t expect big revelationsCollege basketball | Corsairs men ranked No. 17 in California in CCCMBCA poll
Basel, 9 December 2024 - Roche (SIX: RO, ROG; OTCQX: RHHBY) announced today that it has commenced a tender offer for all of the outstanding shares of common stock of Poseida Therapeutics, Inc. (Poseida) (NASDAQ: PSTX) at a price of $9.00 per share in cash, plus a non-tradeable contingent value right (CVR) to receive certain contingent payments of up to an aggregate of $4.00 per share in cash. The tender offer is being made pursuant to the previously announced merger agreement dated as of November 25, 2024 among Roche Holdings, Inc., an indirect wholly owned subsidiary of Roche Holding Ltd, Blue Giant Acquisition Corp., a wholly owned subsidiary of Roche Holdings, Inc., and Poseida. The tender offer period will expire at one minute following 11:59 p.m., New York City time on 7 January, 2025, unless the offer is extended. Roche has filed a tender offer statement on Schedule TO with the United States Securities and Exchange Commission (SEC). Blue Giant Acquisition Corp. is the acquirer in the tender offer. The Offer to Purchase contained within the Schedule TO sets out the terms and conditions of the tender offer. Poseida has also filed a Solicitation/Recommendation Statement with the SEC on Schedule 14D-9, which includes the unanimous recommendation of the Poseida board of directors that Poseida stockholders tender their shares in the tender offer. Closing of the tender offer is conditioned upon customary closing conditions, including the receipt of required regulatory approvals, and there being validly tendered and not validly withdrawn a majority of the outstanding shares of Poseida common stock. The offer is not subject to any financing condition. Following successful completion of the tender offer, any shares not acquired in the tender offer will be acquired in a second step merger at the same price of $9.00 per share, plus the CVR. The closing of the transaction is expected to take place in the first quarter of 2025. The complete terms and conditions are set out in the Offer to Purchase, which was filed with the SEC today, December 9, 2024. Poseida stockholders may obtain copies of all of the offering documents, including the Offer to Purchase, free of charge at the SEC's website (www.sec.gov) or by directing a request for the Solicitation/Recommendation Statement on Schedule 14D-9 to Poseida's website at www.poseida.com or the Offer to Purchase and the other related materials to MacKenzie Partners, Inc., the Information Agent for the offer, toll free at (800) 322-2885 (or please call (212) 929-5500 if you are located outside the U.S. or Canada) or via email at [email protected] . Before making any decision with respect to the Offer, investors are urged to read the Offer to Purchase and related documents, as well as the Solicitation/Recommendation Statement, because they contain important information about the Offer. About Poseida Therapeutics Poseida Therapeutics is a clinical-stage biopharmaceutical company advancing differentiated allogeneic cell therapies and genetic medicines with the capacity to cure. The Company's pipeline includes investigational allogeneic CAR-T cell therapies for hematologic cancers, autoimmune diseases, and solid tumours, as well as investigational in vivo genetic medicines that address patient populations with high unmet medical need. The Company's approach is based on its proprietary genetic editing platforms, including its non-viral transposon-based DNA delivery system, Cas-CLOVERTM Site-Specific Gene Editing System Booster Molecule and nanoparticle gene delivery technologies, as well as in-house GMP cell therapy manufacturing. The Company has formed strategic collaborations with Roche and Astellas to unlock the promise of cell therapies for cancer patients. About Roche Founded in 1896 in Basel, Switzerland, as one of the first industrial manufacturers of branded medicines, Roche has grown into the world's largest biotechnology company and the global leader in in-vitro diagnostics. The company pursues scientific excellence to discover and develop medicines and diagnostics for improving and saving the lives of people around the world. We are a pioneer in personalised healthcare and want to further transform how healthcare is delivered to have an even greater impact. To provide the best care for each person we partner with many stakeholders and combine our strengths in Diagnostics and Pharma with data insights from the clinical practice. For over 125 years, sustainability has been an integral part of Roche's business. As a science-driven company, our greatest contribution to society is developing innovative medicines and diagnostics that help people live healthier lives. Roche is committed to the Science Based Targets initiative and the Sustainable Markets Initiative to achieve net zero by 2045. Genentech, in the United States, is a wholly owned member of the Roche Group. Roche is the majority shareholder in Chugai Pharmaceutical, Japan. For more information, please visit www.roche.com . All trademarks used or mentioned in this release are protected by law. Roche Global Media Relations Phone: +41 61 688 8888 / e-mail: [email protected] Phone: +41 79 407 72 58 Phone: +41 79 935 81 48 Phone: +41 79 771 05 25 Phone: +41 79 568 24 95 Phone: +44 797 32 72 915 Phone: +41 79 461 86 83 Phone: +41 79 327 54 74 Phone: +49 172 6367262 Phone: +41 79 961 92 50 Phone: +41 79 205 27 03 Phone: +41 61 68-75284 e-mail: [email protected] Phone: +41 61 68-88027 e-mail: [email protected] Phone: +41 61 68-84814 e-mail: [email protected] Phone: +1 650 225 3217 e-mail: [email protected] This communication may include statements that are not statements of historical fact, or "forward-looking statements,” within the meaning of the federal securities laws, including with respect to Roche's proposed acquisition of Poseida. Any express or implied statements that do not relate to historical or current facts or matters are forward-looking statements. These statements are generally identified by words or phrases such as "believe”, "anticipate”, "expect”, "intend”, "plan”, "will”, "may”, "should”, "estimate”, "predict”, "project”, "strategy”, "potential”, "continue” or the negative of such terms or other similar expressions. Such statements include, but are not limited to, the ability of Roche and Poseida to complete the transactions contemplated by the merger agreement, including each party's ability to satisfy the conditions to the consummation of the offer contemplated thereby and the other conditions set forth in the merger agreement and statements about the expected timetable for completing the transaction. These statements are based upon the current beliefs and expectations of Roche and Poseida's management and are subject to significant risks and uncertainties. There can be no guarantees that the conditions to the closing of the proposed transaction will be satisfied on the expected timetable if at all. If underlying assumptions prove inaccurate or risks or uncertainties materialize, actual results may differ materially from those set forth in the forward-looking statements, and you should not place undue reliance on these statements. Risks and uncertainties include, but are not limited to, uncertainties as to the timing of the offer and the subsequent merger; uncertainties as to how many of Poseida's stockholders will tender their shares in the offer; the risk that competing offers or acquisition proposals will be made; the possibility that various conditions to the consummation of the offer and the merger contemplated by the merger agreement may not be satisfied or waived, including that a governmental entity may prohibit, delay or refuse to grant approval for the consummation of the tender offer or the subsequent merger; the ability to obtain necessary regulatory approvals or to obtain them on acceptable terms or within expected timing; the effects of disruption from the transactions contemplated by the merger agreement and the impact of the announcement and pendency of the transactions on Poseida's business; the possibility that the milestone payments related to the contingent value right will never be achieved and that no milestone payment may be made; and the risk of legal proceedings being brought in relation to the transactions and the outcome of such proceedings, including the risk that stockholder litigation in connection with the offer or the merger may result in significant costs of defense, indemnification and liability. The foregoing factors should be read in conjunction with the risks and cautionary statements discussed or identified in Poseida's public filings with the SEC, including the "Risk Factors” section of Poseida's Annual Report on Form 10-K for the year ended December 31, 2023 and subsequent Quarterly Reports on Form 10-Q, Form 8-K and in other filings Poseida makes with the SEC from time to time as well as the tender offer materials to be filed by Roche and its acquisition subsidiary and the Solicitation/Recommendation Statement to be filed by Poseida, in each case as amended by any subsequent filings made with the SEC. Neither Roche nor Poseida undertakes any obligation to publicly update any forward-looking statement, whether as a result of new information, future events or otherwise, except to the extent required by law. Attachment 09122024_Poseida Trade Offer_enBERLIN Germany and France expressed readiness Monday to work with Syria's new government while emphasizing that respect for fundamental human rights and the protection of minorities would be essential conditions for cooperation. The joint position emerged from a phone conversation between German Chancellor Olaf Scholz and French President Emmanuel Macron following the weekend overthrow of longtime Syrian leader Bashar al-Assad by anti-regime forces. “Assad had caused terrible suffering to the Syrian people and great damage to his country,” German government spokesman Steffen Hebestreit quoted the leaders as saying in a statement following their discussion. “Both agreed that they are ready to work with the new rulers on the basis of fundamental human rights and the protection of ethnic and religious minorities,” he stressed. In their conversation, the two leaders emphasized the importance of preserving Syria's territorial integrity and sovereignty, Hebestreit noted. “Both agreed to work together to strengthen the European Union's engagement in Syria, including supporting an inclusive political process in Syria,” he said, adding the leaders would discuss the next steps in close coordination with partners in the region.
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