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As the holiday whirlwind surrounds us, we are reminded how much we should be grateful for: no matter which holidays we celebrate, we have numerous opportunities to congregate with friends and family members and to share the holiday spirit, we exchange material and spiritual gifts, we reach out to people we know and even to people we don’t know, to offer our time, compassion, love and support more than in any other part of the year. So why are we not so happy? Why are most people stressed and overwhelmed and the question “Are you ready for the holiday Season?” often sounds more like a disaster preparedness inquiry than an exciting reminder? Scientists and common folk alike offer various explanations. Harvard scientists warn that the holiday season requires us to keep track of additional duties and responsibilities, so the prefrontal portion of our brain goes on “overdrive” with executive decisions we must make. This high demand can cause a decrease in our memory functions, and stress can even stop the production of new brain cells. Harvard scientists recommend self-evaluating how we spend time over the holidays and considering “breaks” from the festivities to slow down this process. Luckily, once the holidays are over and the season’s stress is over, the normal brain function recovers. Additionally, the winter holidays coincide with months when there is less sunlight because the days are shorter. As a result, some people (roughly 6% of the population) develop Seasonal Affective Disorder (SAD), which is more prevalent in northern climates but can be experienced in Colorado, as well. Factors connected with financial stress contribute in a major way. The pressure to buy gifts for all “on the list” replaces the joy of giving if comparison and unrealistic expectations replace the sense of enjoying gift exchanges as a traditional activity and a way to bond. The need to take part in family activities challenges those who experience family conflicts. Even the most diplomatic of us feel challenged when we must face family members with strong political, religious, or health beliefs and convictions. This discourages many people from attending family gatherings. This avoidance causes the opposite negative feeling of loneliness. Statistics indicate that 75% of Gen Z-ers and 65% of single adults feel lonelier than their peers. No matter the source of holiday stress, December is undoubtedly the most stressful month. The end of the year is a time for evaluating our year of experiences, for scorekeeping and tallying personal and professional goals, and for focusing on “what could have been better” as we begin to craft New Year’s resolutions. This reflection, mixed with social media and sometimes forced family functions, can bring the weight of the world crashing down on you. So, how can you avoid this? Is it even possible? Of course it is, but it’s up to us. Whenever you are feeling the holiday blues, do something small for you. Brew some coffee or tea, take a moment or two, and drink in this moment. Allowing yourself the time to experience the heat radiating from the cup in your hand, the chill on your face as you look at the window, and the warmth the holiday season brings to our relationships through celebration. Focus on the moment and not on the Season. And don’t forget, if you are seriously depressed or anxious, your mental health provider or the providers at the 988 hotline will be happy to help. Happy Season to all from us at GTI! ______________________________________________________________________________ Jenni Guentcheva, LPC, LAC, NCACII co-founded GTI and leads GoodNeighbor LLC, both treatment centers in the heart of Canon City. She has developed and managed multiple mental health and addiction treatment programs in Fremont County since 1999. Jenni’s mission is to create opportunities for her clients, both individuals and fellow professionals. Brian Monahan, B.S., CSCS, is the CEO and co-founder of GTI. Brian is a retired US Army Special Forces operative (Green Beret), a coach, trainer, and a psychotherapist. He is pursuing a second degree in Health Psychology and has dedicated his post-military career to another area of service – the health of the community. Brian and Jenni can be contacted at 719-301-7676 and info@greenthumb-initiative.com.

AUTODESK, INC. ANNOUNCES FISCAL 2025 THIRD QUARTER RESULTSNone

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But do we want to do research on all topics, and shall we try the AI master key on every door? To explore this question, let’s consider the use of AI by genomics experts as an example. In recent years, genomics experts have added unbelievable depth to what we know about the world and ourselves. For example, genetics researchers have revealed facts about when certain animals and plants were domesticated. In another example, researchers used DNA from 30,000-year-old permafrost to create fertile samples of a plant called narrow-leafed campion. Importantly, genetic engineering has facilitated extraordinary advances in the treatment of complicated conditions, such as sickle-cell anemia. Thanks to AI, we are witnessing a dramatic increase in the pace and scalability of genomic exploration. Listen now and subscribe: Apple Podcasts | Spotify | Stitcher | RSS Feed | SoundStack | All Of Our Podcasts But given the risks and possible consequences of AI use in science, should we rush headlong into using AI in all kinds of projects? One relevant example is research on Neanderthals, our closest relatives, who lived about 40,000 years ago. Neanderthals have been studied for several years now through genetic investigation of their fossils and their DNA. Genetic engineering can potentially use ancient DNA and genome editing methods to re-create a Neanderthal or aspects of a Neanderthal’s genetics and physiology. To do this, scientists could start by figuring out the DNA sequence of a Neanderthal by comparing it with the DNA of modern humans, because they are closely related. Then, scientists could use the gene-editing tool known as CRISPR to swap out parts of human DNA with Neanderthal DNA. This process would require a lot of trial and error and might not succeed soon. But based on what we know about genetics, if something is possible, AI can help make it happen faster, cheaper and with less effort. Scientists are excited about these developments because they could facilitate new discoveries and open up many research opportunities in genetic research. With or without AI, research on Neanderthals will proceed. But the extraordinary power of AI could give the final push to these discoveries and facilitate this kind of resurrection. At that point, the scientific community must develop norms and guidelines about how to treat these resurrected beings with dispositions very similar to humans. We would need to carefully consider their rights and well-being almost in the same way as when humans are involved and not as research subjects or artifacts of scientific curiosity. These ethical issues are discussed in more detail in a new paper published in the journal Nature Machine Intelligence. A more holistic question to consider is: Should we prioritize the use of resource-intensive AI, researchers’ time and public funds to resurrect extinct beings? Or should we invest these resources into conserving species that are critically endangered today to prevent biodiversity from more degradation?

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SAN FRANCISCO , Nov. 26, 2024 /PRNewswire/ -- Autodesk, Inc. (NASDAQ: ADSK) today announced the appointment of Janesh Moorjani as the company's chief financial officer, effective December 16, 2024 . Moorjani brings over 20 years of experience in the technology industry, with deep expertise in driving growth and efficiency at scale. Most recently, Moorjani served as CFO and COO of Elastic NV (NYSE: ESTC), the Search AI Company. Reporting to chief executive officer Andrew Anagnost , Moorjani will lead and oversee Autodesk's global finance organization. Moorjani will succeed interim chief financial officer Elizabeth "Betsy" Rafael, who will serve as an advisor to the company through the end of fiscal 2025 and will continue to serve on Autodesk's Board of Directors, resuming her status as an independent director following the transition period and end of her employment by the company. "We are excited to welcome such a high-caliber and seasoned CFO in Janesh," said Andrew Anagnost , president and CEO of Autodesk. "His deep finance and software experience will be instrumental in supporting Autodesk's continued momentum with sustained growth and enhanced profitability. I look forward to partnering with Janesh to drive Autodesk's successful path forward and continue creating additional value for our stockholders. I also thank Betsy for stepping into the interim CFO role at an important time for Autodesk, and for her continued contributions both through the transition and as a qualified and experienced board member moving forward." Moorjani brings strong experience leading dynamic public software companies. He recently was CFO of Elastic since 2017 and assumed the additional responsibilities of COO in 2022. Prior to Elastic, he served in executive and leadership roles at Infoblox, VMware, Cisco, PTC, and Goldman Sachs. He currently serves on the Board of Directors of Cohesity, a leading AI-powered data security and data management company. "I am thrilled to join Autodesk and work with Andrew, the company's strong management team and the Board to capitalize on the compelling growth opportunities we have ahead," said Moorjani. "Autodesk has established a clear leadership position as a technology innovator by providing differentiated and connected solutions that allow customers across industries to design and make anything. I look forward to working with the team to build on Autodesk's strong financial foundation to drive continued growth, profitability and free cash flow to ultimately deliver sustainable stockholder value." ABOUT AUTODESK The world's designers, engineers, builders, and creators trust Autodesk to help them design and make anything. From the buildings we live and work in, to the cars we drive and the bridges we drive over. From the products we use and rely on, to the movies and games that inspire us. Autodesk's Design and Make Platform unlocks the power of data to accelerate insights and automate processes, empowering our customers with the technology to create the world around us and deliver better outcomes for their business and the planet. For more information, visit autodesk.com or follow @autodesk. #MakeAnything Autodesk is a registered trademark of Autodesk, Inc., and/or its subsidiaries and/or affiliates in the USA and/or other countries. All other brand names, product names or trademarks belong to their respective holders. Autodesk reserves the right to alter product and services offerings, and specifications and pricing at any time without notice, and is not responsible for typographical or graphical errors that may appear in this document. SAFE HARBOR STATEMENT This press release contains forward-looking statements that involve risks and uncertainties, including quotations from management, statements regarding our strategies, performance, results, growth, profitability and free cash flow, and all statements that are not historical facts. There are a significant number of factors that could cause actual results to differ materially from statements made in this press release, including: our strategy to develop and introduce new products and services and to move to platforms and capabilities, exposing us to risks such as limited customer acceptance (both new and existing customers), costs related to product defects, and large expenditures; global economic and political conditions, including changes in monetary and fiscal policy, foreign exchange headwinds, recessionary fears, supply chain disruptions, resulting inflationary pressures and hiring conditions; geopolitical tension and armed conflicts, and extreme weather events; costs and challenges associated with strategic acquisitions and investments; our ability to successfully implement and expand our transaction model; dependency on international revenue and operations, exposing us to significant international regulatory, economic, intellectual property, collections, currency exchange rate, taxation, political, and other risks, including risks related to the war against Ukraine launched by Russia and our exit from Russia and the current conflict between Israel and Hamas; inability to predict subscription renewal rates and their impact on our future revenue and operating results; existing and increased competition and rapidly evolving technological changes; fluctuation of our financial results, key metrics and other operating metrics; our transition from up front to annual billings for multi-year contracts; deriving a substantial portion of our net revenue from a small number of solutions, including our AutoCAD-based software products and collections; any failure to successfully execute and manage initiatives to realign or introduce new business and sales initiatives, including our new transaction model for Flex; net revenue, billings, earnings, cash flow, or new or existing subscriptions shortfalls; social and ethical issues relating to the use of artificial intelligence in our offerings; our ability to maintain security levels and service performance meeting the expectations of our customers, and the resources and costs required to avoid unanticipated downtime and prevent, detect and remediate performance degradation and security breaches; security incidents or other incidents compromising the integrity of our or our customers' offerings, services, data, or intellectual property; reliance on third parties to provide us with a number of operational and technical services as well as software; our highly complex software, which may contain undetected errors, defects, or vulnerabilities; increasing regulatory focus on privacy issues and expanding laws; governmental export and import controls that could impair our ability to compete in international markets or subject us to liability if we violate the controls; protection of our intellectual property rights and intellectual property infringement claims from others; the government procurement process; fluctuations in currency exchange rates; our debt service obligations; and our investment portfolio consisting of a variety of investment vehicles that are subject to interest rate trends, market volatility, and other economic factors. Further information on potential factors that could affect the financial results of Autodesk are included in Autodesk's Form 10-K and subsequent Forms 10-Q, which are on file with the U.S. Securities and Exchange Commission. Autodesk disclaims any obligation to update the forward-looking statements provided to reflect events that occur or circumstances that exist after the date on which they were made. View original content to download multimedia: https://www.prnewswire.com/news-releases/autodesk-appoints-janesh-moorjani-as-chief-financial-officer-302316577.html SOURCE Autodesk, Inc.F ormer Prime Minister Dr Manmohan Singh, 92, passed away on Thursday (December 26, 2024). AIIMS in a statement said “With profound grief, we inform the demise of Former Prime Minister of India, Dr. Manmohan Singh, aged 92. He was being treated for age-related medical conditions and had sudden loss of consciousness at home on 26th December 2024. Resuscitative measures were started immediately at home. He was brought to the Medical Emergency at AIIMS, New Delhi at 8:06 PM. Despite all efforts, he could not be revived and was declared dead at 9:51 PM.” Also read: Manmohan Singh, a gentleman politician Dr Singh had retired as member of the Rajya Sabha, representing Rajasthan, in February this year. Before this, he represented Assam in the Upper House for six terms since 1991. Showering praise on his last day in the Rajya Sabha, Prime Minister Narendra Modi had called him an “inspirational example”. “The way Manmohan Singh guided the country for a long time... Whenever our democracy will be mentioned, he will be one of those few esteemed members whose contribution will be always remembered,”Mr Modi had said. Described as a reluctant politician, the high point of Dr. Manmohan Singh’s 10-year long Prime Ministership was his handling of the Indo-U.S. nuclear deal. The economist-turned-politician almost single-handedly turned the tables on the Left parties — providing outside support to the Congress-led United Progressive Alliance — by securing the support of Samajwadi Party (SP) in a crucial trust vote in July 2008 over the India-U.S. nuclear deal. Condoling former PM Manmohan Singh’s demise, the Lok Sabha Speaker in a post in Hindi said “Apart from being an eminent economist and an enlightened politician, he will always be remembered for his gentle and simple behaviour.” In a post in Hindi, Union Home Minister Amit Shah said he was “extremely sad” at the news of the demise of former Prime Minister Dr. Manmohan Singh “I express my condolences to his family and supporters in this hour of grief. May Waheguru grant peace to his soul and give strength to his family to bear this grief.” ​ “The demise of former Prime Minister of the country Dr. Manmohan Singh is sad. He was a skilled politician and economist. Under his leadership, India’s economy got a new direction. The demise of Dr. Manmohan Singh is an irreparable loss for Indian politics. We pray to God for eternal peace of the departed soul.” Bihar CM Nitish Kumar on X. ​ ​ ​ ​Hacker scores 21, Bellarmine beats NAIA Brescia 94-66