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THOUSAND OAKS, Calif. , Dec. 2, 2024 /PRNewswire/ -- Amgen (NASDAQ:AMGN) will present at Citi's 2024 Global Healthcare Conference at 9:30 a.m. ET on Thursday , Dec. 5, 2024. Peter Griffith , executive vice president and chief financial officer at Amgen, Jay Bradner , executive vice president of Research and Development and chief scientific officer at Amgen, and Susan Sweeney , executive vice president of Obesity and Related Conditions at Amgen, will participate in a fireside chat at the conference. The webcast will be broadcast over the internet simultaneously and will be available to members of the news media, investors and the general public. The webcast, as with other selected presentations regarding developments in Amgen's business given by management at certain investor and medical conferences, can be found on Amgen's website, www.amgen.com , under Investors. Information regarding presentation times, webcast availability and webcast links are noted on Amgen's Investor Relations Events Calendar. The webcast will be archived and available for replay for at least 90 days after the event. About Amgen Amgen discovers, develops, manufactures and delivers innovative medicines to help millions of patients in their fight against some of the world's toughest diseases. More than 40 years ago, Amgen helped to establish the biotechnology industry and remains on the cutting-edge of innovation, using technology and human genetic data to push beyond what's known today. Amgen is advancing a broad and deep pipeline that builds on its existing portfolio of medicines to treat cancer, heart disease, osteoporosis, inflammatory diseases and rare diseases. In 2024, Amgen was named one of the "World's Most Innovative Companies" by Fast Company and one of "America's Best Large Employers" by Forbes, among other external recognitions . Amgen is one of the 30 companies that comprise the Dow Jones Industrial Average ® , and it is also part of the Nasdaq-100 Index ® , which includes the largest and most innovative non-financial companies listed on the Nasdaq Stock Market based on market capitalization. Amgen is one of the 30 companies that comprise the Dow Jones Industrial Average and is also part of the Nasdaq-100 index. In 2023, Amgen was named one of "America's Greatest Workplaces" by Newsweek, one of "America's Climate Leaders" by USA Today and one of the "World's Best Companies" by TIME. For more information, visit Amgen.com and follow us on X (formerly known as Twitter), LinkedIn , Instagram , TikTok , YouTube and Threads . Amgen Forward-Looking Statements This news release contains forward-looking statements that are based on the current expectations and beliefs of Amgen. All statements, other than statements of historical fact, are statements that could be deemed forward-looking statements, including any statements on the outcome, benefits and synergies of collaborations, or potential collaborations, with any other company (including BeiGene, Ltd. or Kyowa Kirin Co., Ltd.), the performance of Otezla ® (apremilast) (including anticipated Otezla sales growth and the timing of non-GAAP EPS accretion), our acquisitions of Teneobio, Inc., ChemoCentryx, Inc., or Horizon Therapeutics plc (including the prospective performance and outlook of Horizon's business, performance and opportunities, any potential strategic benefits, synergies or opportunities expected as a result of such acquisition, and any projected impacts from the Horizon acquisition on our acquisition-related expenses going forward), as well as estimates of revenues, operating margins, capital expenditures, cash, other financial metrics, expected legal, arbitration, political, regulatory or clinical results or practices, customer and prescriber patterns or practices, reimbursement activities and outcomes, effects of pandemics or other widespread health problems on our business, outcomes, progress, and other such estimates and results. Forward-looking statements involve significant risks and uncertainties, including those discussed below and more fully described in the Securities and Exchange Commission reports filed by Amgen, including our most recent annual report on Form 10-K and any subsequent periodic reports on Form 10-Q and current reports on Form 8-K. Unless otherwise noted, Amgen is providing this information as of the date of this news release and does not undertake any obligation to update any forward-looking statements contained in this document as a result of new information, future events or otherwise. No forward-looking statement can be guaranteed and actual results may differ materially from those we project. Our results may be affected by our ability to successfully market both new and existing products domestically and internationally, clinical and regulatory developments involving current and future products, sales growth of recently launched products, competition from other products including biosimilars, difficulties or delays in manufacturing our products and global economic conditions. In addition, sales of our products are affected by pricing pressure, political and public scrutiny and reimbursement policies imposed by third-party payers, including governments, private insurance plans and managed care providers and may be affected by regulatory, clinical and guideline developments and domestic and international trends toward managed care and healthcare cost containment. Furthermore, our research, testing, pricing, marketing and other operations are subject to extensive regulation by domestic and foreign government regulatory authorities. We or others could identify safety, side effects or manufacturing problems with our products, including our devices, after they are on the market. Our business may be impacted by government investigations, litigation and product liability claims. In addition, our business may be impacted by the adoption of new tax legislation or exposure to additional tax liabilities. If we fail to meet the compliance obligations in the corporate integrity agreement between us and the U.S. government, we could become subject to significant sanctions. Further, while we routinely obtain patents for our products and technology, the protection offered by our patents and patent applications may be challenged, invalidated or circumvented by our competitors, or we may fail to prevail in present and future intellectual property litigation. We perform a substantial amount of our commercial manufacturing activities at a few key facilities, including in Puerto Rico , and also depend on third parties for a portion of our manufacturing activities, and limits on supply may constrain sales of certain of our current products and product candidate development. An outbreak of disease or similar public health threat, such as COVID-19, and the public and governmental effort to mitigate against the spread of such disease, could have a significant adverse effect on the supply of materials for our manufacturing activities, the distribution of our products, the commercialization of our product candidates, and our clinical trial operations, and any such events may have a material adverse effect on our product development, product sales, business and results of operations. We rely on collaborations with third parties for the development of some of our product candidates and for the commercialization and sales of some of our commercial products. In addition, we compete with other companies with respect to many of our marketed products as well as for the discovery and development of new products. Discovery or identification of new product candidates or development of new indications for existing products cannot be guaranteed and movement from concept to product is uncertain; consequently, there can be no guarantee that any particular product candidate or development of a new indication for an existing product will be successful and become a commercial product. Further, some raw materials, medical devices and component parts for our products are supplied by sole third-party suppliers. Certain of our distributors, customers and payers have substantial purchasing leverage in their dealings with us. The discovery of significant problems with a product similar to one of our products that implicate an entire class of products could have a material adverse effect on sales of the affected products and on our business and results of operations. Our efforts to collaborate with or acquire other companies, products or technology, and to integrate the operations of companies or to support the products or technology we have acquired, may not be successful. There can be no guarantee that we will be able to realize any of the strategic benefits, synergies or opportunities arising from the Horizon acquisition, and such benefits, synergies or opportunities may take longer to realize than expected. We may not be able to successfully integrate Horizon, and such integration may take longer, be more difficult or cost more than expected. A breakdown, cyberattack or information security breach of our information technology systems could compromise the confidentiality, integrity and availability of our systems and our data. Our stock price is volatile and may be affected by a number of events. Our business and operations may be negatively affected by the failure, or perceived failure, of achieving our environmental, social and governance objectives. The effects of global climate change and related natural disasters could negatively affect our business and operations. Global economic conditions may magnify certain risks that affect our business. Our business performance could affect or limit the ability of our Board of Directors to declare a dividend or our ability to pay a dividend or repurchase our common stock. We may not be able to access the capital and credit markets on terms that are favorable to us, or at all. CONTACT: Amgen, Thousand Oaks Elissa Snook , 609-251-1407 (media) Justin Claeys , 805-313-9775 (investors) View original content to download multimedia: https://www.prnewswire.com/news-releases/amgen-to-present-at-citis-2024-global-healthcare-conference-302319891.html SOURCE Amgen
Alabama AD Greg Byrne Says School Will 'Assess' Future Scheduling After CFP SnubIf you've ever found yourself stranded on the side of the road with a flat tire, you understand just how inconvenient and scary it can be, especially if you're in a remote area without access to cell service. That situation can quickly become even more dire if you don't know how to change a tire or you don't have the proper tools. This type of scenario is exactly why it's so important to keep an emergency kit in your car , as well as familiarize yourself with a few basic auto jobs, like tire replacements. When it comes to building your emergency kit, one thing that you should strongly consider adding is a portable tire inflator, especially if you're a car novice. These devices are designed to inflate flat tires on the go. That means that if you end up with a flat in the middle of nowhere, all you have to do is grab your inflator, remove the tire's valve stem cap, and use the tool to fill the tire with air. They're extremely handy in emergency situations, they don't require in-depth mechanical knowledge, and they can make the difference between being stuck for hours and getting home on time. The best part is that portable tire inflators aren't as expensive as you may guess. In fact, Amazon, the online marketplace known for its Prime membership perks , is a great place to look for affordable inflators. We checked out the site's tire inflator inventory for ourselves, and we found six highly rated options that won't break the bank. We selected products based on things like price, features, and user reviews, but we'll cover our methodology later. For now, here are six of the best — and highest-rated — portable tire inflators on Amazon. When shopping for portable tire inflators to keep in your emergency kit, it's important that you look for products that provide various features. While it's not entirely necessary that your portable inflator can be used for multiple purposes, it can be extremely handy to have the added versatility that extra features offer, especially in emergency situations. If you're considering buying a portable tire inflator and you're looking for one that's both highly rated and versatile, you should check out the AstroAI Portable Air Compressor for Car Tires . The inflator is built using AstroAI's ToughUltra technology, which the manufacturer claims increases the tool's service life by 30%, thanks to the durable components. The tool is available in four different color accents, allowing you to personalize your purchase, while the programmable psi setting allows you to set your desired pressure level so that the inflator turns off automatically once it reaches the correct psi. The inflator features a backlit digital screen to help you see your pressure settings in the dark, while a built-in LED light helps you see your way around when removing valve stem caps. The electric tool connects to your car's 12-volt accessory outlet (cigarette lighter) and can be used for vehicle tires, bicycles, and even balloons, and it comes with various nozzles and adaptors. The AstroAI inflator costs $31.98 and features 4.5 out of 5 stars based on nearly 100,000 user reviews. Portable tire inflators come in various shapes and sizes and run using a couple of different power sources. While an electric tool that you connect to your vehicle is fine, it never hurts to consider cordless options. Not only do cordless, battery-powered tools provide enhanced mobility, they can also be extremely handy if your car's battery is dead . There are various cordless portable tire inflators out there. However, if you're looking for a tool that not only helps with flat tires but also dead batteries, you should definitely consider the YaberAuto Portable Car Jump Starter with Air Compressor . Capable of jump-starting dead 12-volt car batteries for gas engines sized up to 9 liters and diesels up to 8 liters, the jump pack is extremely versatile and powerful for its size. It's able to maintain its charge for up to 24 months while in standby mode, while the robust inflator mechanism can pump 20 psi into your tires every two minutes. It comes with nozzles for passenger cars, bicycles, sports balls, and more, and a large LCD screen displays your pressure readings clearly and legibly. The jump starter features a unique internal honeycomb thermal design, allowing it to work in frigid temperatures when other tools might fail, as well as dual USB ports for charging various mobile devices. The YaberAuto jump pack air compressor costs $129.99, comes with a 2-year warranty, and features 4.5 out of 5 stars based on just shy of 2,000 customer reviews. Not every cordless tire inflator comes with a battery jump-start feature. There's nothing wrong with that, as it requires a special kind of bad luck to have a dead battery at the same time as a flat tire. The extra feature is handy to have, but if you're looking for a more affordable yet still highly versatile portable tire inflator, there are plenty of other choices. The AstroAI Cordless Tire Inflator Air Compressor comes with a couple of extra features and could be worth exploring. The tool features solid metal internals and is capable of running for up to 20 minutes at a time. It runs using dual power, meaning you can hook it up to your car using the included cable or run it wirelessly using the 20-volt rechargeable battery. The battery and battery charger are included, and the portable inflator is capable of filling average-sized tires in around four minutes. It comes with a backlit LCD screen that displays current pressure as well as desired pressure, while a built-in LED light helps you navigate in the dark. The tool is designed to be used with cars, but you can also use it to inflate bicycle tires and sporting equipment. It costs $89.99 and features 4.6 out of 5 stars based on a whopping 13,000 user reviews. One thing to keep in mind while shopping on Amazon is that you may encounter a lot of strange brand names . It can be easy to dismiss these brands as cheap or low quality, but there's actually a good reason why companies use such random combinations of letters. Essentially, it boils down to the fact that in order to use Amazon's infrastructure to sell products, stores are required to own a registered trademark and be part of the Amazon Brand Registry. It's a lot easier to trademark a random group of letters than it is to trademark a common and easily recognizable word, which explains the large amount of Amazon stores with odd names. Speaking of Amazon brands with strange and unusual names, LOLSSA makes a Portable Air Compressor and Tire Inflator that you may want to check out. You can use the inflator wirelessly and then recharge it using the included USB-C cable, or if you're in a pinch, you can connect the included power cable to your car's cigarette lighter. LOLSSA claims that the tool can inflate a small car tire to between 28 and 35 psi in just 55 seconds, while the inflator is compatible with passenger vehicles, motorcycles, bicycles, and sporting equipment. It features a digital screen with a pressure gauge function and an emergency flashlight with three modes: SOS, strobe, and LED. The LOLSSA portable tire inflator costs $79.99 and features 4.7 out of 5 stars based on over 2,500 customer reviews. As mentioned, you'll see a lot of Amazon stores with random-letter names. While it's always wise to practice tips to keep your money safe while shopping on Amazon , it's also true that many of these stores are perfectly legitimate, even those with strange names. One of the best ways to determine if an item is a scam or not is to check the reviews — it's not a foolproof way to avoid buying faulty or cheap products, but it goes a long way toward weeding out the blatant scams. This information is important to remember, because some of the highest-rated products on Amazon are sold by brands with those seemingly suspicious names. For example, the UABRLA Portable Tire Inflator and Air Compressor has excellent reviews, despite the bizarre company name, and it could be a solid option to consider if you're looking for an inflator to keep in your emergency kit. Like the previous product, the UABRLA inflator uses dual power sources, which means you can use it wirelessly or connect it to your car. It's capable of inflating an average tire to 35 psi in under five minutes, while its small size makes it easy to use and store. The inflator features a digital display, is compatible with cars, bicycles, motorcycles, and sports equipment, and also functions as a portable power bank. The UABRLA device costs $39.98 and features 4.5 out of 5 stars based on more than 2,000 user reviews. One cool feature that you may want to look for in a portable tire inflator is the ability to charge your devices. We've mentioned that a couple of the products above provide this feature, but it's worth discussing in greater detail. As stated earlier, having a tool with various applications is incredibly handy. While you may be able to charge your devices by connecting to your car — even if you're broken down — it never hurts to have the extra power. And if you do break down due to something other than a flat tire, having access to a portable power bank can be a lifesaver. If you're interested in an inflator that also provides mobile device charging capabilities, you should check out the Hajomel Portable Tire Inflator and Power Bank . The tool claims to provide inflation speeds four times faster than standard devices, and the inflator is capable of filling average-sized tires to between 30 and 36 psi up to 32 times on a single charge. It features a digital display with a built-in pressure gauge and comes with various modes designed for different applications, including cars, motorcycles, bicycles, sports balls, and more. The device can reach a full charge in just three hours using the included USB-C cable, and it features a built-in LED light to help you see what you're doing, as well as the ability to charge your mobile devices. The Hajomel tire inflator costs $39.99 and comes with 4.6 out of 5 stars based on nearly 2,000 customer reviews. We selected the products for this list based on a handful of criteria: price, features, and, of course, user reviews. First of all, we looked for portable tire inflators that don't cost an arm and a leg. Many people imagine automotive tools to be extremely expensive, and that is true to a certain extent. However, you don't have to buy a professional-tier tool just to keep in your emergency kit. Each of the devices covered here costs less than $150, and many of them fall well below the $100-mark. Next, we looked for inflators that provided real utility for drivers. Each of the tools on this list can help you inflate a flat tire, but they also provide various other features, like built-in work lights, mobile device charging, and the ability to jump-start your car. Finally, we checked out the user reviews in an attempt to showcase some of the highest-rated portable inflators you can find on Amazon. Each product covered here has a minimum of 4.5 out of 5 stars based on thousands of customer reviews, and we prioritized products described as convenient, versatile, and powerful. All of that said, remember to do your research. Shopping on Amazon can be an easy and affordable way to get cool and unique products, but you still need to practice safe shopping tips. Remember what we said about brand names and checking reviews, and you shouldn't have any issues getting your items.Black Friday is among the most awaited shopping events of the year. Retailers roll out big discounts, special promotions, and doorbuster deals to draw in crowds both online and in stores. Still, many shoppers ask the question: are Black Friday discounts worth it, or just some clever marketing schemes? The article explores the truth behind Black Friday discounts and tips on how to wade through the frenzy and secure real savings. Black Friday is attractive because it is popularized as a day to save on things that do only come around once in every year. It has transcended from being purely the American phenomenon to encompass different retailers across the world, which have joined in their participation. The anticipation from the event is created through thorough advertisements, countdown to purchases, and limited-period purchase. While some of them are indeed true, others are only the fruit of increased consumer excitement. Retailers understand that urgency around Black Friday will always make people rush to shop because they will be convinced to buy stuff on the spot before discounts are gone. Black Friday discounts often fit into a couple of categories: Doorbusters: These are the very deeply discounted items that exist in limited quantities. They are usually designed to attract people to stores or onto websites fast. However, after they are sold out, other merchandise may not provide as much savings. Percentage-off sales: Some retailers have blanket percentage off of an entire category or store, like "30% off all electronics" or "buy one, get one 50% off." Bundle deals: These offers give a discount on bundles. For instance, when purchasing a laptop , there can be a discounted bundle of the accessories. Flash sales: These are time-bound offers available for only a few hours or even minutes, pushing the urgency to buy right now. While some Black Friday deals are real value, not all discounts look as impressive as they do. Retailers sometimes inflate prices in the weeks leading up to Black Friday, so the discounts seem more significant than they do. Others create "exclusive" deals that seem to be unique to Black Friday but have been available all year in other forms. A popular technique is to sell old models or items whose product cycle is ending at discounted prices. Even though these offers seem to be a bargain, the value they bring might not last long, especially with gadgets or appliances in technology that could soon be overtaken by newer models. Price tracking tools and comparison websites are so important in helping to ensure whether a deal is the real bargain or not. Advanced price monitoring helps keep one from being misled to false discounts, ensuring shopper value for their money in purchasing. To avoid traps of impulsive spending over Black Friday, follow some of these tips: Research the prices beforehand: Use price tracking tools to see the average cost of items before Black Friday. This helps identify real deals versus inflated discounts. Make a list and stick to it: Plan ahead by listing the items needed and their regular prices. This will help focus on genuine savings and avoid impulse buys. Shop early or late: Doorbuster deals are often available only for a short period, so shopping early increases the chance of getting the best bargains. Alternatively, late sales, like Cyber Monday, sometimes offer better deals as retailers try to clear remaining stock. Set a budget: Determine how much to spend and stick to it, even when tempted by seemingly great deals. See if the items purchased can be returned or exchanged easily. Some retailers have a stricter return policy when having holiday sales. Black Friday discounts are worth the hustle and bustle only if approached cautiously and with a well-thought-out strategy. While many deals do indeed offer big savings, others may not be as worthwhile as they seem. If one takes the time to research and set limits and avoids making impulsive purchases, shoppers will be able to navigate the Black Friday frenzy better and make sure that the deals they score are worth it.
President-elect Donald Trump responded to the news of former President Jimmy Carter 's death Sunday afternoon, saying he faced many "challenges" as president but commended Carter for "doing everything in his power to improve the lives of all Americans." In a statement posted on Truth Social, Trump pointed to the "enormous responsibility" it takes to be president, and added that "we all owe him a debt of gratitude" for his service. "I just heard of the news about the passing of President Jimmy Carter. Those of us who have been fortunate to have served as President understand this is a very exclusive club, and only we can relate to the enormous responsibility of leading the Greatest Nation in History. The challenges Jimmy faced as President came at a pivotal time for our country and he did everything in his power to improve the lives of all Americans. For that, we all owe him a debt of gratitude," Trump said. Trump added that he and his wife, Melania, are "thinking warmly of the Carter Family and their loved ones during this difficult time." CLICK HERE TO READ MORE FROM THE WASHINGTON EXAMINER Vice President-elect J.D. Vance reposted Trump's statement on X and said, "Jimmy Carter dedicated his life to serving this country. Our thoughts and prayers go out to his loved ones. May he Rest in Peace." Carter died on Sunday afternoon at 100 years old after entering hospice care in Georgia over a year ago. His death marked the end of the longest life of any former U.S. president.
NoneFLAGSTAR FINANCIAL, INC. APPOINTS BRIAN CALLANAN TO BOARD OF DIRECTORS
Us Weekly has affiliate partnerships. We receive compensation when you click on a link and make a purchase. Learn more! Cyber Monday may be the best time to score deals on household staples, but it’s also the best time to score holiday gifts. While picking the perfect present can be daunting, any beauty lover or skincare junkie is going to love a gift set. To make crossing off everyone on your list effortless, we found some of the best deals on coveted beauty sets that you can shop right now. There’s everything to love about getting the best deals, and then spending the next few weeks making merry instead of going to shopping malls! Scroll on to shop the best makeup, fragrance and skincare sets you can buy right now before the final hours of Cyber Monday. Gift sets are already a good value, and while on sale, they feel like a total steal! Shop our favorites from luxe brands like Clarins, Jo Malone and Estée Lauder. Best Beauty Gift Sets on Sale for Cyber Monday 1. Clarins 12 Days of Beauty Favorites: For the French beauty-lover, score a 12-day Advent calendar chock full of Clarins bestsellers for hydrating, glowing skin. Check the coupon for an extra $10 off — $66 (was $95) at Amazon! 2. Sol de Janeiro Brazilian Bum Bum Starter Kit: This viral cream paired with the brand’s body scrub, oil and perfume is a super luxe present — or a great deal if you want to uplift your winter with a rich, tropical vibe — $172 (was $246) at Amazon! 3. Jo Malone London Little Luxuries Travel Set: This one will be hard to give away! Score four petite Jo Malone items in different fragrances, including Meghan Markle’s favorite, Wood Sage and Sea Salt Cologne — $125 (was $180) at Nordstrom! 4. Petite Maison Spa Package: Gift an at-home spa day with a box full of self-care goodies, including hand cream, face masks and more. One shopper boasts, “If you’re looking for the perfect gift to spoil a special woman in your life, look no further than this! From the moment she unwrapped it, her eyes lit up with excitement!”— $60 (was $75) at Amazon! 5. Iconic London Makeup Set: Iconic London has dreamy makeup staples to give skin a lit-from-within glow this holiday season. With several gift-box options including sweet ornament-style packaging, there’s one for any taste! Grab the set for 25% off before it sells out — $41 (was $55) at Amazon! 6. Estée Lauder Serum and Moisturizer Skin Care Set: For lovers of the iconic beauty brand, grab a fantastic deal on a limited-edition set featuring a full-size face serum and moisturizer. With nearly 25,000 reviews, it’s safe to say the duo delivers on its promise of bouncier, lifted skin — $90 (was $120) at Nordstrom! 7. d’alba Piedmont Gift Set: Just right for holiday travel, get the viral white truffle spray that gives skin a youthful glow. Bonus: It comes with a cosmetics case — $34 (was $42) at Amazon! 8. Clé de Peau Beauté Protect and Replenish Daily Radiance Collection: The celeb-loved luxury skincare brand isn’t on sale often, so if you’re a devotee, this is the time to scoop up this limited-edition holiday set. This one is packed full of skincare heroes used by the likes of Martha Stewart and Dakota Fanning. Check the coupon for 20% off — $288 (was $360) at Amazon! Check our latest news in Google News Check our latest news in Apple News 9. Mario Badescu Best of Body Essentials Kit: A lovely stocking stuffer or white elephant gift, this set comes with winter hydration heroes for the lips, body and hands — $18 (was $25) at Amazon!
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