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mega dread size CAPE CANAVERAL, Fla. — Known across the globe as the stuck astronauts, Butch Wilmore and Suni Williams hit the six-month mark in space Thursday with two more to go. The pair rocketed into orbit on June 5 , the first to ride Boeing's new Starliner crew capsule on what was supposed to be a weeklong test flight. They arrived at the International Space Station the next day, only after overcoming a cascade of thruster failures and helium leaks . NASA deemed the capsule too risky for a return flight, so it will be February before their long and trying mission comes to a close. While NASA managers bristle at calling them stuck or stranded, the two retired Navy captains shrug off the description of their plight. They insist they're fine and accepting of their fate. Wilmore views it as a detour of sorts: "We're just on a different path." NASA astronauts Suni Williams, left, and Butch Wilmore stand together for a photo June 5 as they head to the launch pad at Space Launch Complex 41 in Cape Canaveral, Fla., for their liftoff on the Boeing Starliner capsule to the International Space Station. "I like everything about being up here," Williams told students Wednesday from an elementary school named for her in Needham, Massachusetts, her hometown. "Just living in space is super fun." Both astronauts lived up there before, so they quickly became full-fledged members of the crew, helping with science experiments and chores like fixing a broken toilet, vacuuming the air vents and watering the plants. Williams took over as station commander in September. "Mindset does go a long way," Wilmore said in response to a question from Nashville first graders in October. He's from Mount Juliet, Tennessee. "I don't look at these situations in life as being downers." Boeing flew its Starliner capsule home empty in September, and NASA moved Wilmore and Williams to a SpaceX flight not due back until late February. Two other astronauts were bumped to make room and to keep to a six-month schedule for crew rotations. Boeing Crew Flight Test astronauts Butch Wilmore, left, and Suni Williams pose for a portrait June 13 inside the vestibule between the forward port on the International Space Station's Harmony module and Boeing's Starliner spacecraft. Like other station crews, Wilmore and Williams trained for spacewalks and any unexpected situations that might arise. "When the crews go up, they know they could be there for up to a year," NASA Associate Administrator Jim Free said. NASA astronaut Frank Rubio found that out the hard way when the Russian Space Agency had to rush up a replacement capsule for him and two cosmonauts in 2023, pushing their six-month mission to just past a year. Boeing said this week that input from Wilmore and Williams was "invaluable" in the ongoing inquiry of what went wrong. The company said it is preparing for Starliner's next flight but declined to comment on when it might launch again. NASA also has high praise for the pair. "Whether it was luck or whether it was selection, they were great folks to have for this mission," NASA's chief health and medical officer, Dr. JD Polk, said during an interview with The Associated Press. NASA astronauts Suni Williams and Butch Wilmore, both Expedition 71 flight engineers, make pizza Sept. 9 aboard the International Space Station's galley located inside the Unity module. Items are attached to the galley using tape and Velcro to keep them from flying away in the microgravity environment. On top of everything else, Williams, 59, had to deal with "rumors," as she calls them, of serious weight loss. She insists her weight is the same as it was on launch day, which Polk confirms. During Wednesday's student chat, Williams said she didn't have much of an appetite when she first arrived in space. But now she's "super hungry" and eating three meals a day plus snacks, while logging the required two hours of daily exercise. Williams, a distance runner, uses the space station treadmill to support races in her home state. She competed in Cape Cod's 7-mile Falmouth Road Race in August. She ran the 2007 Boston Marathon up there as well. She has a New England Patriots shirt with her for game days, as well as a Red Sox spring training shirt. "Hopefully I'll be home before that happens — but you never know," she said in November. Husband Michael Williams, a retired federal marshal and former Navy aviator, is caring for their dogs back home in Houston. As for Wilmore, 61, he's missing his younger daughter's senior year in high school and his older daughter's theater productions in college. The astronauts in the video seemed to be in good spirits with one stating, “It’s gonna be delicious.” (Scripps News) "We can't deny that being unexpectedly separated, especially during the holidays when the entire family gets together, brings increased yearnings to share the time and events together," his wife, Deanna Wilmore, told the AP in a text this week. Her husband "has it worse than us" since he's confined to the space station and can only connect via video for short periods. "We are certainly looking forward to February!!" she wrote. A SpaceX Falcon 9 rocket, with a crew of two astronauts, lifts off from launch pad 40 at the Cape Canaveral Space Force Station in Cape Canaveral, Fla., Saturday, Sept. 28, 2024. (AP Photo/Chris O'Meara) A SpaceX Falcon 9 rocket, with a crew of two astronauts, lifts off from launch pad 40 at the Cape Canaveral Space Force Station Saturday, Sept. 28, 2024, in Cape Canaveral, Fla. (AP Photo/Chris O'Meara) NASA astronaut Nick Hague, left, and Roscosmos cosmonaut Aleksandr Gorbunov, left, gives a thumbs up as they leave the Operations and Checkout Building on their way to Launch Complex 40 for a mission to the International Space Station Saturday, Sept. 28, 2024 at Cape Canaveral, Fla., (AP Photo/John Raoux) NASA astronaut Nick Hague, right, and Roscosmos cosmonaut Aleksandr Gorbunov leave the Operations and Checkout building for a trip to the launch pad 40 Saturday, Sept. 28, 2024, at the Kennedy Space Center in Cape Canaveral, Fla. (AP Photo/Chris O'Meara) NASA astronaut Nick Hague, right, talks to his family members as Roscosmos cosmonaut Aleksandr Gorbunov looks on after leaving the Operations and Checkout building for a trip to the launch pad 40 Saturday, Sept. 28, 2024, at the Kennedy Space Center in Cape Canaveral, Fla. Two astronauts are beginning a mission to the International Space Station. (AP Photo/Chris O'Meara) In this image from video provided by NASA, Roscosmos cosmonaut Aleksandr Gorbunov, left, and astronaut Nick Hague travel inside a SpaceX capsule en route to the International Space Station after launching from the Kennedy Space Center in Cape Canaveral, Fla., Saturday, Sept. 28, 2024. (NASA via AP) A SpaceX Falcon 9 rocket, with a crew of two astronauts, lifts off from launch pad 40 at the Cape Canaveral Space Force Station Saturday, Sept. 28, 2024, in Cape Canaveral, Fla. (AP Photo/Chris O'Meara) A SpaceX Falcon 9 rocket, with a crew of two astronauts, lifts off from launch pad 40 at the Cape Canaveral Space Force Station in Cape Canaveral, Fla., Saturday, Sept. 28, 2024. (AP Photo/Chris O'Meara) A SpaceX Falcon 9 rocket with a crew of two lifts off from launch pad 40 at the Cape Canaveral Space Force Station Saturday, Sept. 28, 2024 at Cape Canaveral, Fla. (AP Photo/John Raoux) The Falcon 9's first stage booster returns to Landing Zone 1 at the Cape Canaveral Space Force Station Saturday, Sept. 28, 2024 at Cape Canaveral, Fla. (AP Photo/John Raoux) A SpaceX Falcon 9 rocket with a crew of two lifts off from launch pad 40 at the Cape Canaveral Space Force Station Saturday, Sept. 28, 2024 at Cape Canaveral, Fla. (AP Photo/John Raoux) Get local news delivered to your inbox!

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EDMONTON — The latest checkup on famed Edmonton elephant Lucy finds her in good shape ahead of her 50th birthday -- but not healthy enough to be relocated to join a herd. Gary Dewar, the director of Edmonton Valley Zoo, says experts have determined the 49-year-old elephant's respiratory issues won't allow her to travel short or long distances. He says the gentle giant's overall health is good considering her age and says she continues to enjoy her retirement. The Asian elephant arrived at the zoo when she was two years old. In recent years, Lucy has made international headlines as protesters have been calling for her to be moved so she could spend the final years of her life with other elephants. Among the advocates for Lucy's freedom was famous U.S. television game show host Bob Barker, who said before his death in 2023 that elephants were not meant to brave Canada's harsh winter climate. This report by The Canadian Press was first published Dec. 4, 2024. Fakiha Baig, The Canadian PressA fresh coat of paint and track lighting has turned a former gender-affirming clothing shop into an art gallery, library and gathering space with a similar community-minded mission. Read this article for free: Already have an account? To continue reading, please subscribe: * A fresh coat of paint and track lighting has turned a former gender-affirming clothing shop into an art gallery, library and gathering space with a similar community-minded mission. Read unlimited articles for free today: Already have an account? A fresh coat of paint and track lighting has turned a former gender-affirming clothing shop into an art gallery, library and gathering space with a similar community-minded mission. MIKAELA MACKENZIE / FREE PRESS From left: Revolution Wellness Centre’s Carla Taylor co-founded Matter Queer Space with spouses Bre Cristobal Calma and Nix Cristobal Calma in the basement below the centre. Matter Queer Space Manitoba — located in the previous basement home of Closet Space at 433 Graham Ave. — is a non-profit venture designed to offer LGBTTQ+ and BIPOC (Black, Indigenous and people of colour) Winnipeggers a welcoming place to connect over art, books and shared interests. “A lot of (hanging out) happens in bars and not all queers are into that scene.” Matter was founded by spouses Bre and Nix Cristobal Calma and friend Carla Taylor, who runs Revolution Wellness Centre on the building’s main floor. “There aren’t a lot, if any, spaces in the community right now to just come and be together,” Bre says, adding the goal is to offer barrier-free programming to visitors of all ages. “Having a queer intergenerational space, that’s a really big thing because the queer community can be segmented in some ways,” Nix says. “A lot of (hanging out) happens in bars and not all queers are into that scene.” The basement is bright and cosy, with a gallery room at one end, library shelving in the middle and seating areas throughout. There are plans to add a gender-affirming retail shop in the future. MIKAELA MACKENZIE / FREE PRESS Matter Queer Space Manitoba is a new art gallery, library and programming space for the local LGBTTQ+ and BIPOC community. In addition to art shows and workshops, the programming schedule is going to be community-driven, meaning anyone is invited to pitch and host public or private events that fit with Matter’s mandate. Ideas discussed so far include yoga classes, movie nights, craft groups and a reading club. “Not a book club, where you have to sit and talk; instead, you sit and collectively read together. You’re not necessarily forced into socialization that may be uncomfortable for some people, but it still gives you an opportunity to be out and around people that you know will accept you as you are,” Taylor explains. MIKAELA MACKENZIE / FREE PRESS While Matter Queer Space Manitoba launches Saturday with an open house and maker’s market, the gallery space will open in January. It’s the kind of gathering that speaks to the project’s overall ethos. “We picture this space as a bit of an introvert haven,” Taylor says. Matter launches Saturday with an open house and mini maker’s market from 11 a.m. to 5 p.m. featuring goods from 15 queer vendors, with sensory-friendly and mask-required shopping during the first two hours. The first art exhibit is set to open in January, featuring the work of local visual artist and muralist Cat Hues, a.k.a. Pink Panda. Matter’s founders believe it will be one of the city’s first permanent gallery spaces designated specifically for showing work by marginalized LGBTTQ+ artists. “It’s surprising it hasn’t been done yet because there are a lot of wonderful, racialized, trans, queer, non-binary artists,” says Nix, who is also a multimedia artist. “We picture this space as a bit of an introvert haven.” With every exhibit, the featured artist will be invited to host talks and art-making workshops for the public, the results of which will be turned into a group show curated by the artist. “We really want to challenge the idea of meritocracy. This idea that you have to have a degree in art curation to curate an exhibit,” Bre says. MIKAELA MACKENZIE / FREE PRESS Matter’s library — which is the continuation of a project started by Taylor and friend Renu Shonek in 2019 — is stocked with borrowable books by bell hooks, Joshua Whitehead, James Baldwin and others. A book drive by Winnipeg’s Willow Press has brought dozens of new titles into the fold and Matter is accepting donations of used books of any genre by queer BIPOC authors. “We know these books are out there, but not everyone does. It’s nice to bring them together in a collection to learn about more authors and more talent in the community, and even to encourage some of our community members in their own writing and creativity,” Taylor says. To reduce financial barriers for visitors, the programming at Matter will be offered on a pay-what-you-can basis. Winnipeg Jets Game Days On Winnipeg Jets game days, hockey writers Mike McIntyre and Ken Wiebe send news, notes and quotes from the morning skate, as well as injury updates and lineup decisions. Arrives a few hours prior to puck drop. Other than donations collected through a GoFundMe campaign, the organizers have been footing the bill for the project out-of-pocket. They hope to find sustainable, long-term funding in the future. “This has definitely been a passion project and a labour of love. The three of us are just community members, none of us have experience doing any of this — running galleries or libraries — but it’s a space that we wanted to see and we knew there was a need for,” says Bre. “Nobody else was doing it, so someone had to.” Visit for more information. eva.wasney@winnipegfreepress.com Eva Wasney has been a reporter with the Arts & Life department since 2019. . Every piece of reporting Eva produces is reviewed by an editing team before it is posted online or published in print — part of the ‘s tradition, since 1872, of producing reliable independent journalism. Read more about , and . Our newsroom depends on a growing audience of readers to power our journalism. If you are not a paid reader, please consider . Our newsroom depends on its audience of readers to power our journalism. Thank you for your support.

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First and only subcutaneous anti-CD38 therapy demonstrating potential to prevent end-organ damage, and extend progression-free survival and overall survival based on findings from Phase 3 AQUILA study SAN DIEGO , Dec. 8, 2024 /PRNewswire/ -- Johnson & Johnson (NYSE: JNJ) today announced data from the Phase 3 AQUILA study showing that DARZALEX FASPRO ® (daratumumab and hyaluronidase-fihj) significantly delayed progression from high-risk smoldering multiple myeloma (SMM) to active multiple myeloma (MM) and extended overall survival compared to the current standard of care of active monitoring. 1 The data were presented for the first time as an oral presentation at the 2024 American Society of Hematology (ASH) Annual Meeting ( Abstract #773 ), as part of the Press Program and were selected for the Best of ASH session. In the AQUILA study, 194 patients received DARZALEX FASPRO ® and 196 patients were actively monitored per current standard of care treatment for high-risk SMM. At a median follow-up of 65.2 (range, 0-76.6) months, patients who received DARZALEX FASPRO ® showed statistically significant improved progression-free survival (PFS; defined as progression to active MM as assessed according to International Myeloma working Group (IMWG) diagnostic criteria for MM [SLiM-CRAB] or death) than the active monitoring group; 63.1 percent versus 40.8 percent of patients remained progression-free at 60 months (hazard ratio [HR], 0.49; 95 percent confidence interval [CI], 0.36-0.67; P 1%) injection-site reaction was injection-site erythema. These local reactions occurred a median of 5 minutes (range: 0 minutes to 6.5 days) after starting administration of DARZALEX FASPRO ® . Monitor for local reactions and consider symptomatic management. Neutropenia Daratumumab may increase neutropenia induced by background therapy. Monitor complete blood cell counts periodically during treatment according to manufacturer's prescribing information for background therapies. Monitor patients with neutropenia for signs of infection. Consider withholding DARZALEX FASPRO ® until recovery of neutrophils. In lower body weight patients receiving DARZALEX FASPRO ® , higher rates of Grade 3-4 neutropenia were observed. Thrombocytopenia Daratumumab may increase thrombocytopenia induced by background therapy. Monitor complete blood cell counts periodically during treatment according to manufacturer's prescribing information for background therapies. Consider withholding DARZALEX FASPRO ® until recovery of platelets. Embryo-Fetal Toxicity Based on the mechanism of action, DARZALEX FASPRO ® can cause fetal harm when administered to a pregnant woman. DARZALEX FASPRO ® may cause depletion of fetal immune cells and decreased bone density. Advise pregnant women of the potential risk to a fetus. Advise females with reproductive potential to use effective contraception during treatment with DARZALEX FASPRO ® and for 3 months after the last dose. The combination of DARZALEX FASPRO ® with lenalidomide, thalidomide, or pomalidomide is contraindicated in pregnant women because lenalidomide, thalidomide, and pomalidomide may cause birth defects and death of the unborn child. Refer to the lenalidomide, thalidomide, or pomalidomide prescribing information on use during pregnancy. Interference With Serological Testing Daratumumab binds to CD38 on red blood cells (RBCs) and results in a positive indirect antiglobulin test (indirect Coombs test). Daratumumab-mediated positive indirect antiglobulin test may persist for up to 6 months after the last daratumumab administration. Daratumumab bound to RBCs masks detection of antibodies to minor antigens in the patient's serum. The determination of a patient's ABO and Rh blood type are not impacted. Notify blood transfusion centers of this interference with serological testing and inform blood banks that a patient has received DARZALEX FASPRO ® . Type and screen patients prior to starting DARZALEX FASPRO ® . Interference With Determination of Complete Response Daratumumab is a human immunoglobulin G (IgG) kappa monoclonal antibody that can be detected on both the serum protein electrophoresis (SPE) and immunofixation (IFE) assays used for the clinical monitoring of endogenous M-protein. This interference can impact the determination of complete response and of disease progression in some DARZALEX FASPRO ® -treated patients with IgG kappa myeloma protein. ADVERSE REACTIONS In multiple myeloma, the most common adverse reaction (≥20%) with DARZALEX FASPRO ® monotherapy is upper respiratory tract infection. The most common adverse reactions with combination therapy (≥20% for any combination) include fatigue, nausea, diarrhea, dyspnea, insomnia, headache, pyrexia, cough, muscle spasms, back pain, vomiting, hypertension, upper respiratory tract infection, peripheral sensory neuropathy, constipation, pneumonia, and peripheral edema. The most common hematology laboratory abnormalities (≥40%) with DARZALEX FASPRO ® are decreased leukocytes, decreased lymphocytes, decreased neutrophils, decreased platelets, and decreased hemoglobin. Please click here to see the full Prescribing Information for DARZALEX FASPRO ® . DARZALEX ® INDICATIONS AND IMPORTANT SAFETY INFORMATION INDICATIONS DARZALEX ® (daratumumab) is indicated for the treatment of adult patients with multiple myeloma: In combination with bortezomib, melphalan, and prednisone in newly diagnosed patients who are ineligible for autologous stem cell transplant In combination with lenalidomide and dexamethasone in newly diagnosed patients who are ineligible for autologous stem cell transplant and in patients with relapsed or refractory multiple myeloma who have received at least one prior therapy In combination with bortezomib, thalidomide, and dexamethasone in newly diagnosed patients who are eligible for autologous stem cell transplant In combination with pomalidomide and dexamethasone in patients who have received at least one prior line of therapy including lenalidomide and a proteasome inhibitor In combination with carfilzomib and dexamethasone in patients with relapsed or refractory multiple myeloma who have received one to three prior lines of therapy In combination with bortezomib and dexamethasone in patients who have received at least one prior therapy As monotherapy in patients who have received at least three prior lines of therapy including a proteasome inhibitor (PI) and an immunomodulatory agent or who are double-refractory to a PI and an immunomodulatory agent CONTRAINDICATIONS DARZALEX ® is contraindicated in patients with a history of severe hypersensitivity (eg, anaphylactic reactions) to daratumumab or any of the components of the formulation. WARNINGS AND PRECAUTIONS Infusion-Related Reactions DARZALEX ® can cause severe and/or serious infusion-related reactions including anaphylactic reactions. These reactions can be lifethreatening, and fatal outcomes have been reported. In clinical trials (monotherapy and combination: N=2066), infusion-related reactions occurred in 37% of patients with the Week 1 (16 mg/kg) infusion, 2% with the Week 2 infusion, and cumulatively 6% with subsequent infusions. Less than 1% of patients had a Grade 3/4 infusion-related reaction at Week 2 or subsequent infusions. The median time to onset was 1.5 hours (range: 0 to 73 hours). Nearly all reactions occurred during infusion or within 4 hours of completing DARZALEX ® . Severe reactions have occurred, including bronchospasm, hypoxia, dyspnea, hypertension, tachycardia, headache, laryngeal edema, pulmonary edema, and ocular adverse reactions, including choroidal effusion, acute myopia, and acute angle closure glaucoma. Signs and symptoms may include respiratory symptoms, such as nasal congestion, cough, throat irritation, as well as chills, vomiting, and nausea. Less common signs and symptoms were wheezing, allergic rhinitis, pyrexia, chest discomfort, pruritus, hypotension and blurred vision. When DARZALEX ® dosing was interrupted in the setting of ASCT (CASSIOPEIA) for a median of 3.75 months (range: 2.4 to 6.9 months), upon re-initiation of DARZALEX ® , the incidence of infusion-related reactions was 11% for the first infusion following ASCT. Infusion-related reactions occurring at re-initiation of DARZALEX ® following ASCT were consistent in terms of symptoms and severity (Grade 3 or 4: Netflix has revealed its content slate for December 2024, with the much-awaited second season of Squid Game topping the list. The show still remains Netflix's most-viewed non-English TV series. Other highlights include Season 6 of Virgin River and a bunch of movies and TV shows arriving on December 1. These include Little , Midway , and Project X . Here are some other titles to look forward to. Netflix's comedy and documentary specials for December Netflix's December lineup includes a number of comedy and documentary specials. On December 3, Fortune Feimster returns with her third Netflix comedy special, Fortune Feimster: Crushing It . The next day, Netflix will drop a fascinating docuseries, Churchill at War , which examines Winston Churchill 's pivotal role in World War II. Another documentary, The Only Girl in the Orchestra , will highlight trailblazing double bassist Orin O'Brien's journey as the first female musician in the New York Philharmonic. Netflix's global content and family shows for December Netflix will release a bunch of international content in December. The Children's Train (December 4) is an Italian film about a mother sending her son to northern Italy for a better life. From Thailand comes Tomorrow and I , a series imagining a dystopian future where technology clashes with traditional customs. For family viewers, That Christmas is an unforgettable tale of how the worst snowstorm in history changes everyone's plans in Wellington-on-Sea, including Santa's! Netflix's anime, series, and film releases in early December Netflix will continue its content rollout with BEASTARS: Final Season: Part 1 on December 5. The anime follows characters Louis and Haru as they navigate university life. The same day, the streaming platform will release Black Doves , a series about a spy seeking truth and vengeance after her lover's murder. Jentry Chau vs the Underworld is also set to premiere; it tells the story of a teenager rediscovering her suppressed fiery powers as she confronts literal demons. Netflix's mid-December content highlights Oscar and Grammy-winner Jamie Foxx returns to the stage with his comedy event Jamie Foxx: What Had Happened Was... on December 10. On top of that, Polo , a sports series executive produced by Prince Harry and Meghan Markle , gives an exclusive look at the world of polo. The series follows elite players competing in the high-stakes US Open Polo Championship in Wellington, Florida. Beloved Hindi teen romance series Mismatched will arrive on December 13. Netflix's late December content and year-end specials Netflix will end the year with some big releases. On December 26, Squid Game: Season 2 will premiere, bringing back the global hit series. On the last day of the year, Netflix will release Avicii - I'm Tim , a documentary on musical prodigy Tim Bergling, and Avicii - My Last Show , a film capturing his last performance. Michelle Buteau: A Buteau-ful Mind at Radio City Music Hall will debut as comedian Michelle Buteau's second Netflix comedy special.

The Prime Minister is set to promise a named, contactable police officer for every neighbourhood in England and Wales as he lays out his “plan for change” on Thursday. In a speech billed as setting out the “next phase” of his Government , Sir Keir Starmer is expected to detail ambitious “milestones” for achieving the five missions laid out in Labour’s manifesto. He will say: “My Government was elected to deliver change, and today marks the next step. People are tired of being promised the world, but short-term sticking plaster politics letting them down.” But Conservative leader Kemi Badenoch has already branded the speech an “emergency reset” after a challenging five months in office. Downing Street said the milestones would focus on raising living standards, rebuilding Britain, ending hospital backlogs, putting more police on the beat, giving children the best start in life and securing home-grown energy. Among the promises expected to be announced on Thursday is a guarantee that every neighbourhood will have a named, contactable police officer responsible for dealing with local issues. The Prime Minister is expected to describe the move as “a relief to millions of people scared to walk their streets they call home”, and promise a range of policing reforms to improve performance alongside £100 million to support neighbourhood policing. Labour has already pledged to recruit 13,000 new police officers, PCSOs and special constables, which would bring the total police workforce to a level above its 2010 peak. Police numbers following the 2010 election, before rising again after 2019 as the previous government pledged to recruit 20,000 police officers. While the number of officers reached record levels, the number of PCSOs and special constables continued to decline. The promise of a named officer for each community is intended to improve relations between the police and the public. Home Secretary Yvette Cooper said: “Out neighbourhood policing guarantee is about more than just increasing numbers. It’s about rebuilding the vital connection between the public and the police. “This marks a return to the founding principles of British policing – where officers are part of the communities they serve.” But the Conservatives said only a third of the 13,000 new recruits would be full police officers, while the £100 million would not cover what was needed to pay for them, leading to cuts elsewhere. Chris Philp, the shadow home secretary, said: “The Conservatives recruited over 20,000 extra police officers and gave the police an extra £922 million for policing this year, ensuring the police could protect the public and prosecute more criminals. “Starmer has once again misled the public by claiming to recruit an extra 13,000 officers when the actual number is 3,000, and even that is not properly funded.” Sir Keir’s policing announcement is expected to be one of several focused on the “missions” Labour set out in its manifesto, which were securing the “highest sustained growth” in the G7, making Britain a “clean energy superpower”, halving serious violent crime, breaking down “barriers to opportunity” and building an NHS “fit for the future”. Along with the targets set to be announced on Thursday, the Prime Minister is expected to propose a significant programme of public sector reform as his Government continues to face questions on how it will achieve its aims without further raising taxes or borrowing. The Prime Minister will say: “Hard working Brits are going out grafting every day but are getting short shrift from a politics that should serve them. “They reasonably want a stable economy, their country to be safe, their borders secure, more cash in their pocket, safer streets in their town, opportunities for their children, secure British energy in their home, and an NHS that is there when they need it. “My mission-led Government will deliver.”Newmont's EVP & COO Viljoen sells $374,310 in stock

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Trump nominates Marty Makary, a critic of some COVID-19 health measures, to lead the FDAAlberta minister wants to see $100B in data centre infrastructure in next five years EDMONTON — Alberta's Technology Minister Nate Glubish says he's hoping to see $100 billion worth of artificial intelligence data centres under construction within the next five years. Jack Farrell, The Canadian Press Dec 4, 2024 12:10 PM Dec 4, 2024 12:20 PM Share by Email Share on Facebook Share on X Share on LinkedIn Print Share via Text Message Nate Glubish shakes hands with Alberta Premier Danielle Smith after Glubish was sworn into cabinet as Minister of Technology and Innovations in Edmonton, Monday, Oct. 24, 2022. Glubish says he's hoping to see $100 billion worth of artificial intelligence data centres under construction within the next five years.THE CANADIAN PRESS/Jason Franson EDMONTON — Alberta's Technology Minister Nate Glubish says he's hoping to see $100 billion worth of artificial intelligence data centres under construction within the next five years. Such centres are filled with computer servers used by companies like Meta to develop and train large-scale artificial intelligence models. Glubish says Meta, as well as other major companies including Google and Amazon, are on the hunt for space to build more facilities, and he wants Alberta to be an option. He says landing some data centres would create jobs and bring in much needed new tax revenue for the province. Glubish also says that since Alberta's electricity grid regulations allows for off-grid power generation, he thinks the province is an ideal location. He says allowing for off-grid power connections where power generators supply data centres directly also means there's less risk for Albertans, as there wouldn't be major drains on the electrical grid. This report by The Canadian Press was first published Dec. 4, 2024. Jack Farrell, The Canadian Press See a typo/mistake? Have a story/tip? This has been shared 0 times 0 Shares Share by Email Share on Facebook Share on X Share on LinkedIn Print Share via Text Message Get your daily Victoria news briefing Email Sign Up More Alberta News CFIA makes second cucumber recall in less than a week in B.C., Alberta Dec 4, 2024 1:17 PM Smith noncommittal on overriding Charter as court challenge looms over trans bills Dec 4, 2024 1:10 PM 'We do need to harvest': Alberta government expands cougar hunting areas, quotas Dec 4, 2024 11:51 AM

President-elect Donald Trump on Friday nominated Dr. Marty Makary to lead the Food and Drug Administration , selecting a surgeon and author who gained national attention for opposing vaccine mandates and some other public health measures during the COVID-19 pandemic. Makary, a professor at Johns Hopkins University, is the latest in a string of Trump nominees who have declared the U.S. health system “broken” and in need of a shakeup. In books and articles Makary has decried the overprescribing of drugs, the use of pesticides on foods and the undue influence of pharmaceutical and insurance companies over doctors and government regulators. He will need to be confirmed by the Republican-led Senate to take the post. Trump announced the nomination in a statement Friday night, saying Makary “will restore FDA to the gold standard of scientific research, and cut the bureaucratic red tape at the agency to make sure Americans get the medical cures and treatments they deserve.” Headquartered in the Maryland suburbs outside Washington, the 18,000 employees of the FDA are responsible for the safety and effectiveness of prescription drugs , vaccines and medical devices as well as a swath of other consumer goods, including food , cosmetics and vaping products . Altogether those products represent an estimated 20% of U.S. consumer spending annually, or $2.6 trillion. Makary gained prominence on Fox News and other conservative outlets for his contrarian views during the COVID-19 pandemic. He questioned the need for masking and, though not opposed to the COVID-19 vaccine, had concerns about vaccinations in young children. The Centers for Disease Control and Prevention estimated that COVID-19 vaccinations prevented more than 686,000 U.S. deaths in 2020 and 2021 alone. While children faced much lower rates of hospitalization and death from the virus, medical societies including the American Academy of Pediatrics concluded that vaccinations significantly reduced severe disease in the age group. Trained as a surgeon and cancer specialist, Makary was part of a vocal group of physicians calling for greater emphasis on herd immunity to stop the virus, or the idea that mass infections would quickly lead to population-level protection. In a February 2021 Wall Street Journal piece , he wrote that “COVID will be mostly gone by April, allowing Americans to resume normal life.” That summer the delta variant of the virus ripped through the U.S. , followed by omicron in the winter, leading to hundreds of thousands of additional deaths. If confirmed, Makary would be expected to report to anti-vaccine activist Robert F. Kennedy Jr. , Trump's pick to oversee the nation’s Department of Health and Human Services , which includes the FDA. Makary does not share Kennedy’s discredited views on vaccines , but he has a similar distrust of the pharmaceutical industry. Makary has lamented how drugmakers used misleading data to urge doctors to prescribe OxyContin and other opioids as low-risk, non-addictive pain relievers. That marketing was permitted under FDA-approved labeling from the 1990s, suggesting the drugs were safe for common ailments like back pain. In more recent years, the FDA has come under fire for approving drugs for Alzheimer's , ALS and other conditions based on incomplete data that failed to show meaningful benefits for patients. A push toward greater scrutiny of drug safety and effectiveness would be a major reversal at FDA, which for decades has focused on speedier drug approvals . That trend has been fueled by industry lobbying and fees paid by drugmakers to help the FDA hire additional reviewers. Kennedy has proposed ending those payments, which would require billions in new funding from the federal budget. Other administration priorities would likely run into similar roadblocks. For instance, Kennedy wants to bar drugmakers from advertising on TV , a multibillion-dollar market that supports many TV and cable networks. The Supreme Court and other conservative judges would likely overturn such a ban on First Amendment grounds that protect commercial speech, experts note. Makary would also inherit a raft of ongoing projects at the FDA kicked off by outgoing Commissioner Robert Califf, including the reorganization of the agency's food division and plans to regulate artificial intelligence in medical technology. In the event of other controversial initiatives under Trump, career staffers may simply drag the work out until a new administration comes to power. “The bureaucracy can wait anybody out, and that’s an attitude I think you’ll hear a lot,” said Wayne Pines, a former FDA official under Republican and Democratic administrations. The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Science and Educational Media Group. The AP is solely responsible for all content.Happy Valley star James Norton is a busy man: as well as starring in new Netflix movie Joy and upcoming ITV series Playing Nice , he's got a couple of historical dramas in the pipeline. One of those is House of Guinness , a new show from Peaky Blinders boss Steven Knight which tells the story of the family behind the iconic Irish brewery, and also boasts Louis Partridge, Anthony Boyle and Jack Gleeson among its cast. It sounds like a blast, and so when we spoke to Norton about Joy during the London Film Festival last month, we couldn't resist asking him what to expect from the series. "We are half just over halfway through the first series, hence my very dark hair and everything – tinted eyebrows and all that jazz," he said. Keep up to date with all the dramas - from period to crime to comedy By entering your details, you are agreeing to our terms and conditions and privacy policy . You can unsubscribe at any time. "I'm playing an Irish man from Dublin, and it's really fun. It's a really, really fun job. Steven Knight is at his best, he's blessing us with these incredible scripts. And it's just a delight." Expanding a little more on the show, he explained: "It's the Guinness world of 1860, at the moment they exploded onto the world and became this kind of international phenomenon. [It's] such an interesting time, politically." And he added: "It's got beer, it's got this, like, eccentric family, we've got these, you know, Steven Knight characters all kind of jostling and playing, fighting, f**king. It's just, like, really exciting." Read more: James Norton on bursting into tears reading Joy script and Happy Valley memories Outlander stars know what the future is for Bree and Roger The show was initially announced by Netflix back in March, with Knight commenting at the time: "The Guinness dynasty is known the world over – wealth, poverty, power, influence, and great tragedy are all intertwined to create a rich tapestry of material to draw from. "I’ve always been fascinated by their stories and am excited to bring the characters to life for the world to see." We can't wait! House of Guinness is coming soon to Netflix. Sign up for Netflix from £4.99 a month . Netflix is also available on Sky Glass and Virgin Media Stream . Check out more of our Drama coverage or visit our TV Guide and Streaming Guide to find out what's on. For more from the biggest stars in TV, listen to The Radio Times Podcast .

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Residents have responded with mixed reactions after a city council announced for almost five kilometres along a busy nature strip that's become . , which encompasses much of and southern suburbs, announced overnight that "after receiving numerous complaints" it will install no parking signs along a 4.5km stretch of Anzac Parade between Matraville and La Perouse. From today it will start warning owners to remove their vehicles from the grassed nature strip, with plans to "create formalised parking bays to support residents" in the works — however they won't be for boats or caravans. "Parked vehicles make it more dangerous for pedestrians in these green spaces and create safety risks by blocking the view of oncoming traffic," council said in a statement. The portion of Anzac Parade in question is frequently used by boat owners for storage, angering those who say the area is already lacking adequate parking. Speaking to Yahoo News Australia, a Randwick City spokesperson confirmed the new signage will be installed in the next five to 10 days. "Two variable message signs have been installed on site informing people of the change," he told Yahoo. "Vehicles can continue to park legally along Anzac Parade." He said storage of "all sorts of larger vehicles" — including boats, trailers, caravans and vans — "presents a problem". "Warning notices will be placed on vehicles currently left in the area and letters will be sent to car owners where possible," council said. There will be a grace period to allow vehicles to move and adjust to the change before $129 fines will be issued. Responding to the announcement on social media, dozens of passionate locals weighed in with their opinions. Some called for "formalised paid long-term parking" for the vehicles which they said "clog up residential streets" — something that has become . Meanwhile others questioned the idea from council, calling it "nonsense" and saying it will merely push the problem elsewhere. "I appreciate this move however it’s also going to push these vehicles and boats into neighbouring streets where parking is at a premium," one person argued. "I applaud council [for] considering ... street parking but they need to look at the bigger picture," said another. "The issue of vehicles including trailers parking on the grass of Anzac Parade ... provides a temporary solution in the absence of fenced off parking areas." "People are trying to park their recreation vehicles OFF the roads to reduce congestion. The council is certainly not there for its rate payers. One person complains and yet again no community engagement or alternatives put in place," a third commented on the council's post. "Them being on the grass is a lot safer than on the street what nonsense is this council trying to pull," one local said. Council stated online that once the vehicles have been removed, it would add more native and indigenous plants "to enhance the area" and help with "screening, shade and reducing noise".Telehealth Update: DEA/HHS Temporary Rule, Medicare Coverage of Telehealth Services, Potential for Increased Oversight, and What to Watch For in 2025

Fortnite’s XP cap for Creative has increased, but players remain frustrated over how long it takes to level up in Battle Royale. The advent of Fortnite Chapter 6 ushered in various changes across the board, the most controversial being an XP nerf that severely stifled progression . Previously, each mode offered its daily challenges to drive XP gain – Chapter 6 unified the system. Backlash from the community has resulted in some improvements, so far. A December 4 update now guarantees players can earn up to 4,000,000 playtime XP per week in LEGO, Fortnite OG, and Reload modes. However, another mode has received a significant XP buff, all while players in the popular Battle Royale experience struggle with leveling up. Fortnite’s Creative mode receives XP cap boost after backlash As initially reported by ItsADAMO_ , Epic has buffed the XP cap in Creative. The cap is reportedly four million per week based on the findings of Fortnite player JimGrindsXP . Players are already applauding this swift change by the developers. However, one large portion of the community remains upset – those who primarily play Battle Royale. Since the start of Chapter 6 , Battle Royale players have lamented how much longer it takes to level up compared to past chapters. Some users believe it’s now “impossible to level up while playing BR mode” because of the weekly XP cap and removal of milestones. “I played 4 hours today and gained 3 levels. This is garbage,” another person commented in a Reddit thread. Others think adding playtime XP for Battle Royale would help resolve the issue. Related: At the time of writing, Epic has yet to address this part of the XP backlash, nor is there any indication that Battle Royale-related XP boosts are incoming. Players can only hope the changes for Creative, OG, Reload, and LEGO mean the more popular mode will soon receive the same attention.

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